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Ann Thorac Surg 2000;70:742-750
© 2000 The Society of Thoracic Surgeons

Original articles: cardiovascular

Rapid cardiopulmonary support for children with complex congenital heart disease

Jeffrey P. Jacobs, MDb, Jorge W. Ojito, BS, CCPa, Todd W. McConaghey, CCPa, Bryan D. Boden, BS, CCPa, Anthony C. Chang, MDa, Abdul Aldousany, MDa, Evan M. Zahn, MDa, Redmond P. Burke, MDa

a Divisions of Cardiovascular Surgery and Cardiology, Miami Children’s Hospital, Miami, USA
b Division of Thoracic and Cardiovascular Surgery, All Children’s Hospital, University of South Florida College of Medicine, St. Petersburg, Florida, USA

Address reprint requests to Dr Jacobs, Division of Thoracic and Cardiovascular Surgery, All Children’s Hospital, 603 Seventh St S, Suite 450, St. Petersburg, FL 33701
e-mail: jjacobs1{at}compuserve.com

Background. Extracorporeal membrane oxygenation has limitations in children with congenital heart disease (prolonged setup times, increased postoperative blood loss, and difficulty during transport). We developed a miniaturized cardiopulmonary support circuit to address these limitations.

Patients and Methods. The cardiopulmonary support system includes a preassembled, completely heparin-coated circuit, a BP-50 Bio-Medicus centrifugal pump, a Minimax plus membrane oxygenator, a Bio-Medicus flow probe, and a Bio-trend hematocrit/oxygen saturation monitor. Short tubing length permits a 250-mL bloodless prime in less than 5 minutes. From 1995 to 1997, 23 children with congenital heart disease were supported with this technique.

Results. Overall survival to discharge was 48% (11 of 23 patients). Survival to discharge was 80% (4 of 5) in the preoperative support group, 20% (1 of 5) in the postoperative failure to wean from cardiopulmonary bypass group, 44% (4 of 9) in the group placed on support postoperatively after transfer to the intensive care unit, and 50% (2 of 4 patients) in the nonoperative group. Neonatal cardiopulmonary support survival to discharge was 46% (6 of 13 patients).

Conclusions. This pediatric cardiopulmonary support system is safe and effective. Advantages over conventional extracorporeal membrane oxygenation include rapid setup time, decreased postoperative blood loss, and simplified transport.




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