HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Donato D’Agostino Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bortone, A. S. Articles by de Luca Tupputi Schinosa, L. Search for Related Content PubMed PubMed Citation Articles by Bortone, A. S. Articles by de Luca Tupputi Schinosa, L.

Ann Thorac Surg 2000;70:1115-1118
© 2000 The Society of Thoracic Surgeons

---

Supplement: cardiothoracic techniques & technologies

Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year

^a Department of Emergency and Transplantation, Division of Cardiac Surgery, University of Bari School of Medicine, Bari, Italy
^b Institute of Nuclear Medicine, University of Bari School of Medicine, Bari, Italy
^c Division of Cardiology, "L. Sacco" Hospital, Milan, Italy

Address reprint requests to Dr Bortone, Haemodynamic Laboratory, Division of Cardiac Surgery, University of Bari, Ospedale Consorziale Policlinico, Pizza G. Cesare, 11, 70124 Bari, Italy
e-mail: emobort{at}libero.it

Presented at the Sixth Annual Cardiothoracic Techniques and Technologies Meeting 2000, Ft Lauderdale, FL, Jan 27–29, 2000.

Background. Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function.

Methods. During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole.

Results. All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. However, there was an improvement in thickness of the subendocardial-treated areas in systole that persisted during follow-up.

Conclusions. The use of SPET and TTE validates the clinical efficacy of PTMR.

This article has been cited by other articles:

				M. Ruel, R. A. Kelly, and F. W. Sellke Therapeutic Angiogenesis, Transmyocardial Laser Revascularization, and Cell Therapy Card. Surg. Adult, January 1, 2003; 2(2003): 715 - 750. [Full Text]