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Ann Thorac Surg 2000;69:1445-1447
© 2000 The Society of Thoracic Surgeons


Original articles: Cardiovascular

Dynamic cardiomyoplasty: long-term clinical results in patients with dilated cardiomyopathy

Domingo M. Braile, MD, PhDa, Moacir F. Godoy, PhDa, Grácia H. Thèvenard, MDb, Rubens S. Thèvenard, MD, PhDb, Maria C.V.B. Braile, MDb, João C.F. Leal, MDb, Max Schaldach, PhDa

a Faculdade de Medicina de São José do Rio Preto-Medical School FAMERP,São Paulo, Brazil
b Hospital Beneficência Portuguesa de São José do Rio Preto, São Paulo, Brazil

Address reprint requests to Dr Braile, Av Juscelino Kubitschek 3101, 15091-450, São José do Rio Preto, São Paulo, Brazil
e-mail: domingo{at}braile.com.br

Background. Dynamic cardiomyoplasty has been considered to be an effective method of surgical treatment of patients with end-stage heart failure, and is an alternative to heart transplantation.

Methods. We critically evaluated the long-term course of 52 patients with dilated cardiomyopathy who underwent dynamic cardiomyoplasty and were followed-up for up to 110 months.

Results. Dilated cardiomyopathy was due to undetermined cause in 42 patients (80.8%), Chagas disease in 8 (15.4%), viral infection in 1 (1.9%), and peripartum cardiomyopathy in 1 (1.9%). In the nonchagasic group the survival rates were 79.5% ± 6.1%, 67.8% ± 7.1%, 53.7% ± 8.3%, 49.9% ± 8.3%, 14.9% ± 12.2%, and 14.9% ± 12.2%, respectively, at 12, 24, 48, 60, 80 and 110 months of follow-up. In the chagasic patients the survival rates were 37.5% ± 17.1%, 12.5% ± 11.7%, 12.5% ± 11.7% and 0%, respectively, at 12, 24, 48, and 60 months of follow-up, making chagasic cardiomyopathy a possible contraindication for dynamic cardiomyoplasty.

Conclusions. There was no correlation between the clinical improvement and hemodynamic data. Ventricular fibrillation was a frequent cause of immediate and late death, suggesting the need for prophylactic use of antiarrhythmic drugs or implantable cardioverter/defibrillators.




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