|
|
||||||||
Ann Thorac Surg 2000;69:1198-1204
© 2000 The Society of Thoracic Surgeons
a Bristol Heart Institute, Bristol Royal Infirmary, Bristol, United Kingdom
Address reprint requests to Dr Angelini, Bristol Heart Institute, Bristol Royal Infirmary, Bristol, BS2 8HW, United Kingdom
e-mail: g.d.angelini{at}bristol.ac.uk
Background. We sought to investigate the effect of multiple coronary artery bypass grafting (CABG) with or without cardiopulmonary bypass (CPB) on the perioperative inflammatory response.
Methods. Sixty patients undergoing CABG were randomly assigned to one of two groups: (A) on pump with conventional CPB and cardioplegic arrest, and (B) off pump on the beating heart. Serum samples were collected for estimation of neutrophil elastase, interleukin 8 (IL-8), C3a, and C5a preoperatively and at 1, 4, 12, and 24 hours postoperatively. Furthermore, white blood cell (WBC), neutrophil, and monocyte counts were carried out preoperatively and at 1, 12, 36 and 60 hours postoperatively. Overall incidence of infection and perioperative clinical outcome were also recorded.
Results. The groups were similar in terms of age, weight, gender ratio, extent of coronary disease, left ventricular function, and number of grafts per patient. Neutrophil elastase concentration peaked early after CPB in the on-pump group, with a decline with time. Repeated-measures analysis of variance between groups and comparisons at each time point (modified Bonferroni) showed elastase concentrations were significantly higher in the on-pump than the off-pump group (both p < 0.0001). IL-8 increased significantly after surgery in the on-pump group, with no decline during the observation period (p = 0.01 vs off pump). C3a and C5a rose early after surgery in both groups when compared with baseline values. Postoperative WBC, neutrophil, and monocyte counts were significantly higher in the on-pump than the off-pump group (p < 0.01). Finally, the incidence of postoperative overall infections was significantly higher in the on-pump group (p < 0.0001 vs off pump).
Conclusions. CABG on the beating heart is associated with a significant reduction in inflammatory response and postoperative infection when compared with conventional revascularization with CPB and cardioplegic arrest.
Related Article
Ann. Thorac. Surg. 2000 69: 1204.
This article has been cited by other articles:
![]() |
F. Formica, F. Broccolo, A. Martino, J. Sciucchetti, V. Giordano, L. Avalli, G. Radaelli, O. Ferro, F. Corti, C. Cocuzza, et al. Myocardial revascularization with miniaturized extracorporeal circulation versus off pump: Evaluation of systemic and myocardial inflammatory response in a prospective randomized study. J. Thorac. Cardiovasc. Surg., May 1, 2009; 137(5): 1206 - 1212. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Caputo, H. Alwair, C. A. Rogers, M. Ginty, C. Monk, S. Tomkins, A. Mokhtari, and G. D. Angelini Myocardial, Inflammatory, and Stress Responses in Off-Pump Coronary Artery Bypass Graft Surgery With Thoracic Epidural Anesthesia Ann. Thorac. Surg., April 1, 2009; 87(4): 1119 - 1126. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. P. Sakwa, R. W. Emery, F. L. Shannon, J. M. Altshuler, D. Mitchell, D. Zwada, and A. R. Holter Coronary artery bypass grafting with a minimized cardiopulmonary bypass circuit: a prospective, randomized trial. J. Thorac. Cardiovasc. Surg., February 1, 2009; 137(2): 481 - 485. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. M. Carvalho, E. A Gabriel, and T. A Salerno Pulmonary Protection During Cardiac Surgery: Systematic Literature Review Asian Cardiovasc Thorac Ann, December 1, 2008; 16(6): 503 - 507. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. H. Moller, L. Penninga, J. Wetterslev, D. A. Steinbruchel, and C. Gluud Clinical outcomes in randomized trials of off- vs. on-pump coronary artery bypass surgery: systematic review with meta-analyses and trial sequential analyses Eur. Heart J., November 1, 2008; 29(21): 2601 - 2616. [Abstract] [Full Text] [PDF] |
||||
![]() |
X. Sun, L. Zhang, P. C. Hill, R. Lowery, A. T. Lee, R. E. Molyneaux, P. J. Corso, and S. W. Boyce Is incidence of postoperative vasoplegic syndrome different between off-pump and on-pump coronary artery bypass grafting surgery? Eur. J. Cardiothorac. Surg., October 1, 2008; 34(4): 820 - 825. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. J. Pegg, J. B. Selvanayagam, T. D. Karamitsos, R. J. Arnold, J. M. Francis, S. Neubauer, and D. P. Taggart Effects of Off-Pump Versus On-Pump Coronary Artery Bypass Grafting on Early and Late Right Ventricular Function Circulation, April 29, 2008; 117(17): 2202 - 2210. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Pepino, P. Oliviero, F. Petteruti, L. di Tommaso, M. Monaco, and P. Stassano Left Heart Pump-Assisted Beating Heart Coronary Surgery in High-Risk Patients Asian Cardiovasc Thorac Ann, April 1, 2008; 16(2): 159 - 161. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. G Raja and G. D Dreyfus Current Status of Off-pump Coronary Artery Bypass Surgery Asian Cardiovasc Thorac Ann, April 1, 2008; 16(2): 164 - 178. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Farneti, S Sbrana, D Spiller, A. Cerillo, F Santarelli, D Di Dario, P. Del Sarto, and M Glauber Reduction of blood coagulation and monocyte-platelet interaction following the use of a minimal extracorporeal circulation system (Synergy(R)) in coronary artery bypass grafting (CABG) Perfusion, January 1, 2008; 23(1): 49 - 56. [Abstract] [PDF] |
||||
![]() |
J. W. Hammon Extracorporeal Circulation: The Response of Humoral and Cellular Elements of Blood to Extracorporeal Circulation Card. Surg. Adult, January 1, 2008; 3(2008): 370 - 389. [Full Text] |
||||
![]() |
T. M. Dewey and M. J. Mack Myocardial Revascularization without Cardiopulmonary Bypass Card. Surg. Adult, January 1, 2008; 3(2008): 633 - 654. [Full Text] |
||||
![]() |
A. Radaelli, C. Loardi, M. Cazzaniga, G. Balestri, C. DeCarlini, M. G. Cerrito, E. N. Cusa, L. Guerra, S. Garducci, D. Santo, et al. Inflammatory Activation During Coronary Artery Surgery and Its Dose-Dependent Modulation by Statin/ACE-Inhibitor Combination Arterioscler. Thromb. Vasc. Biol., December 1, 2007; 27(12): 2750 - 2755. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. L. Hannan, C. Wu, C. R. Smith, R. S.D. Higgins, R. E. Carlson, A. T. Culliford, J. P. Gold, and R. H. Jones Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery: Differences in Short-Term Outcomes and in Long-Term Mortality and Need for Subsequent Revascularization Circulation, September 4, 2007; 116(10): 1145 - 1152. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Guizilini, W. J. Gomes, S. M. Faresin, D. W. Bolzan, E. Buffolo, A. C. Carvalho, and A. A.V. De Paola Influence of Pleurotomy on Pulmonary Function After Off-Pump Coronary Artery Bypass Grafting Ann. Thorac. Surg., September 1, 2007; 84(3): 817 - 822. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. G. Healy, A. E. Wood, A. O'Neill, J. F. McCarthy, J. M. Fitzpatrick, and R. W. Watson Can preoperative modelling of individual neutrophil adhesion responses predict renal morbidity? Eur. J. Cardiothorac. Surg., June 1, 2007; 31(6): 1088 - 1093. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Glauber, A. Farneti, S. Bevilacqua, and J. Karimov Pump-assisted beating heart surgery MMCTS, February 19, 2007; 2007(0219): 943. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Motallebzadeh, J. M. Bland, H. S. Markus, J. C. Kaski, and M. Jahangiri Neurocognitive Function and Cerebral Emboli: Randomized Study of On-Pump Versus Off-Pump Coronary Artery Bypass Surgery Ann. Thorac. Surg., February 1, 2007; 83(2): 475 - 482. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. J. Allen, W. T. McBride, T. J. McMurray, A. S. Phillips, S. P. Penugonda, G. Campalani, I. S. Young, and M. A. Armstrong Cell Salvage Alters the Systemic Inflammatory Response After Off-Pump Coronary Artery Bypass Grafting Surgery Ann. Thorac. Surg., February 1, 2007; 83(2): 578 - 585. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Castiglioni, A. Verzini, F. Pappalardo, N. Colangelo, L. Torracca, A. Zangrillo, and O. Alfieri Minimally Invasive Closed Circuit Versus Standard Extracorporeal Circulation for Aortic Valve Replacement Ann. Thorac. Surg., February 1, 2007; 83(2): 586 - 591. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. R. Hoda, H. El-Achkar, E. Schmitz, T. Scheffold, H. O. Vetter, and R. De Simone Systemic Stress Hormone Response in Patients Undergoing Open Heart Surgery With or Without Cardiopulmonary Bypass Ann. Thorac. Surg., December 1, 2006; 82(6): 2179 - 2186. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Kamiya, T. Kofidis, A. Haverich, and U. Klima Preliminary experience with the mini-extracorporeal circulation system (Medtronic resting heart system) Interactive CardioVascular and Thoracic Surgery, December 1, 2006; 5(6): 680 - 682. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Sedrakyan, A. W. Wu, A. Parashar, E. B. Bass, and T. Treasure Off-Pump Surgery Is Associated With Reduced Occurrence of Stroke and Other Morbidity as Compared With Traditional Coronary Artery Bypass Grafting: A Meta-Analysis of Systematically Reviewed Trials * Supplemental Appendix I Stroke, November 1, 2006; 37(11): 2759 - 2769. [Full Text] [PDF] |
||||
![]() |
J. Tatoulis, S. Rice, P. Davis, J. C. Goldblatt, and S. Marasco Patterns of postoperative systemic vascular resistance in a randomized trial of conventional on-pump versus off-pump coronary artery bypass graft surgery. Ann. Thorac. Surg., October 1, 2006; 82(4): 1436 - 1444. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. S. Just, T. Muller, M. Hartrumpf, and J. M. Albes First experience with closed circuit/centrifugal pump extracorporeal circulation: cellular trauma, coagulatory, and inflammatory response Interactive CardioVascular and Thoracic Surgery, October 1, 2006; 5(5): 646 - 648. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. E. Falagas, E. S. Rosmarakis, K. Rellos, A. Michalopoulos, G. Samonis, and S. N. Prapas Microbiologically documented nosocomial infections after coronary artery bypass surgery without cardiopulmonary bypass. J. Thorac. Cardiovasc. Surg., September 1, 2006; 132(3): 481 - 490. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Niranjan, G. Asimakopoulos, A. Karagounis, G. Cockerill, M. Thompson, and V. Chandrasekaran Effects of cell saver autologous blood transfusion on blood loss and homologous blood transfusion requirements in patients undergoing cardiac surgery on- versus off-cardiopulmonary bypass: a randomised trial. Eur. J. Cardiothorac. Surg., August 1, 2006; 30(2): 271 - 277. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. G. Shann, D. S. Likosky, J. M. Murkin, R. A. Baker, Y. R. Baribeau, G. R. DeFoe, T. A. Dickinson, T. J. Gardner, H. P. Grocott, G. T. O'Connor, et al. An evidence-based review of the practice of cardiopulmonary bypass in adults: A focus on neurologic injury, glycemic control, hemodilution, and the inflammatory response. J. Thorac. Cardiovasc. Surg., August 1, 2006; 132(2): 283 - 290.e3. [Full Text] [PDF] |
||||
![]() |
C. A. Skrabal, Y. H. Choi, A. Kaminski, M. Steiner, G. Kundt, G. Steinhoff, and A. Liebold Circulating endothelial cells demonstrate an attenuation of endothelial damage by minimizing the extracorporeal circulation. J. Thorac. Cardiovasc. Surg., August 1, 2006; 132(2): 291 - 296. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Deblier, A. M. Sadowska, A. Janssens, I. Rodrigus, and W. A. DeBacker Markers of inflammation and oxidative stress in patients undergoing CABG with CPB with and without ventilation of the lungs: a pilot study Interactive CardioVascular and Thoracic Surgery, August 1, 2006; 5(4): 387 - 391. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. E. Lehmann, S. Schroeder, W. Hartmann, O. Dewald, M. Book, S. U. Weber, J.-C. Schewe, and F. Stuber A single nucleotide polymorphism of macrophage migration inhibitory factor is related to inflammatory response in coronary bypass surgery using cardiopulmonary bypass. Eur. J. Cardiothorac. Surg., July 1, 2006; 30(1): 59 - 63. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. S. Lingaas, P. K. Hol, R. Lundblad, K. A. Rein, L. Mathisen, H.-J. Smith, R. Andersen, E. Thaulow, T. I. Tonnesen, J. L. Svennevig, et al. Clinical and Radiologic Outcome of Off-Pump Coronary Surgery at 12 Months Follow-Up: A Prospective Randomized Trial Ann. Thorac. Surg., June 1, 2006; 81(6): 2089 - 2095. [Abstract] [Full Text] [PDF] |
||||
![]() |
K.-B. Kim, K. R. Cho, J.-S. Choi, and H.-J. Lee Right Gastroepiploic Artery for Revascularization of the Right Coronary Territory in Off-Pump Total Arterial Revascularization: Strategies to Improve Patency Ann. Thorac. Surg., June 1, 2006; 81(6): 2135 - 2141. [Abstract] [Full Text] [PDF] |
||||
![]() |
S P Schoen, T Kittner, S Bohl, M U Braun, G Simonis, A Schmeisser, and R H Strasser Transcatheter closure of atrial septal defects improves right ventricular volume, mass, function, pulmonary pressure, and functional class: a magnetic resonance imaging study Heart, June 1, 2006; 92(6): 821 - 826. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. M. Bical, Y. Fromes, D. Gaillard, M. Fischer, O. Ponzio, P. Deleuze, M.-F. Gerhardt, and F. Trivin Comparison of the inflammatory response between miniaturized and standard CPB circuits in aortic valve surgery. Eur. J. Cardiothorac. Surg., May 1, 2006; 29(5): 699 - 702. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Quaniers, J. Leruth, A. Albert, R. R. Limet, and J.-O. Defraigne Comparison of inflammatory responses after off-pump and on-pump coronary surgery using surface modifying additives circuit. Ann. Thorac. Surg., May 1, 2006; 81(5): 1683 - 1690. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Beghi, F. Nicolini, A. Agostinelli, B. Borrello, A. M. Budillon, F. Bacciottini, M. Friggeri, A. Costa, L. Belli, L. Battistelli, et al. Mini-Cardiopulmonary Bypass System: Results of a Prospective Randomized Study Ann. Thorac. Surg., April 1, 2006; 81(4): 1396 - 1400. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. M. Draaisma, M. G. Hazekamp, N. Anes, P. H. Schoof, C. E. Hack, A. Sturk, and R. A.E. Dion Phosphorylcholine Coating of Bypass Systems Used for Young Infants Does Not Attenuate the Inflammatory Response Ann. Thorac. Surg., April 1, 2006; 81(4): 1455 - 1459. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. G Raja and G. D Dreyfus Modulation of Systemic Inflammatory Response after Cardiac Surgery Asian Cardiovasc Thorac Ann, December 1, 2005; 13(4): 382 - 395. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Fung, R. R. Fiscus, A. P. C. Yim, G. D. Angelini, and A. A. Arifi The Potential Use of Type-5 Phosphodiesterase Inhibitors in Coronary Artery Bypass Graft Surgery Chest, October 1, 2005; 128(4): 3065 - 3073. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. P. Cannon, S. R. Mehta, and S. F. Aranki Balancing the Benefit and Risk of Oral Antiplatelet Agents in Coronary Artery Bypass Surgery Ann. Thorac. Surg., August 1, 2005; 80(2): 768 - 779. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. McKeown and A. E. Epstein Future Directions: American College of Chest Physicians Guidelines for the Prevention and Management of Postoperative Atrial Fibrillation After Cardiac Surgery Chest, August 1, 2005; 128(2_suppl): 61S - 64S. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. L. Gillespie, K. A. Gryskiewicz, C. M. White, J. Kluger, C. Humphrey, S. Horowitz, and C. I. Coleman Effect of aprotinin on the frequency of postoperative atrial fibrillation or flutter Am. J. Health Syst. Pharm., July 1, 2005; 62(13): 1370 - 1374. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Bainbridge, J. Martin, and D. Cheng Off Pump Coronary Artery Bypass Graft Surgery Versus Conventional Coronary Artery Bypass Graft Surgery: A Systematic Review of the Literature Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 2005; 9(1): 105 - 111. [Abstract] [PDF] |
||||
![]() |
F. Kerendi, J. D. Puskas, J. M. Craver, W. A. Cooper, E. L. Jones, O. M. Lattouf, J. D. Vega, and R. A. Guyton Emergency Coronary Artery Bypass Grafting Can Be Performed Safely Without Cardiopulmonary Bypass in Selected Patients Ann. Thorac. Surg., March 1, 2005; 79(3): 801 - 806. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. W. Staton, W. H. Williams, E. M. Mahoney, J. Hu, H. Chu, P. G. Duke, and J. D. Puskas Pulmonary Outcomes of Off-Pump vs On-Pump Coronary Artery Bypass Surgery in a Randomized Trial Chest, March 1, 2005; 127(3): 892 - 901. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Mierdl, C. Byhahn, V. Lischke, T. Aybek, G. Wimmer-Greinecker, S. Dogan, S. Viehmeyer, P. Kessler, and K. Westphal Segmental Myocardial Wall Motion During Minimally Invasive Coronary Artery Bypass Grafting Using Open and Endoscopic Surgical Techniques Anesth. Analg., February 1, 2005; 100(2): 306 - 314. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. J Murphy, R. Ascione, and G. D Angelini Coronary artery bypass grafting on the beating heart: surgical revascularization for the next decade? Eur. Heart J., December 1, 2004; 25(23): 2077 - 2085. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. A Black, S. Ghosh, K. Sin, T. Spyt, and R. Pillai Off-Pump Coronary Artery Bypass Surgery Asian Cardiovasc Thorac Ann, December 1, 2004; 12(4): 379 - 386. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. M. Morariu, Y. J. Gu, R. C.G. G. Huet, W. A. Siemons, G. Rakhorst, and W. v. Oeveren Red blood cell aggregation during cardiopulmonary bypass: a pathogenic cofactor in endothelial cell activation? Eur. J. Cardiothorac. Surg., November 1, 2004; 26(5): 939 - 946. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. I. Kapetanakis, S. C. Stamou, M. K.C. Dullum, P. C. Hill, E. Haile, S. W. Boyce, A. S. Bafi, K. R. Petro, and P. J. Corso The Impact of Aortic Manipulation on Neurologic Outcomes After Coronary Artery Bypass Surgery: A Risk-Adjusted Study Ann. Thorac. Surg., November 1, 2004; 78(5): 1564 - 1571. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Wynne and M. Botti Postoperative Pulmonary Dysfunction in Adults After Cardiac Surgery With Cardiopulmonary Bypass: Clinical Significance and Implications for Practice Am. J. Crit. Care., September 1, 2004; 13(5): 384 - 393. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Weissman Pulmonary Complications After Cardiac Surgery Seminars in Cardiothoracic and Vascular Anesthesia, September 1, 2004; 8(3): 185 - 211. [Abstract] [PDF] |
||||
![]() |
R de Vroege, F te Meerman, L Eijsman, W R Wildevuur, C. R. Wildevuur, and W van Oeveren Induction and detection of disturbed homeostasis in cardiopulmonary bypass Perfusion, September 1, 2004; 19(5): 267 - 276. [Abstract] [PDF] |
||||
![]() |
T. Velissaris, A. T. M. Tang, M. Murray, R. L. Mehta, P. J. Wood, D. A. Hett, and S. K. Ohri A prospective randomized study to evaluate stress response during beating-heart and conventional coronary revascularization Ann. Thorac. Surg., August 1, 2004; 78(2): 506 - 512. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. J.M.G. van der Heijden, H. M. Nathoe, E. W.L. Jansen, and D. E. Grobbee Meta-analysis on the effect of off-pump coronary bypass surgery Eur. J. Cardiothorac. Surg., July 1, 2004; 26(1): 81 - 84. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Y. P. Wan, A. A. Arifi, S. Wan, J. H. Y. Yip, A. D. L. Sihoe, K.H. Thung, E. M. C. Wong, and A. P. C. Yim Beating heart revascularization with or without cardiopulmonary bypass: Evaluation of inflammatory response in a prospective randomized study J. Thorac. Cardiovasc. Surg., June 1, 2004; 127(6): 1624 - 1631. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Athanasiou, O. Aziz, O. Mangoush, A. Weerasinghe, S. Al-Ruzzeh, S. Purkayastha, J. Pepper, M. Amrani, B. Glenville, and R. Casula Do off-pump techniques reduce the incidence of postoperative atrial fibrillation in elderly patients undergoing coronary artery bypass grafting? Ann. Thorac. Surg., May 1, 2004; 77(5): 1567 - 1574. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Naito, M. Nakajima, H. Inoue, and K. Tsuchiya Successful CABG in a patient with paroxysmal nocturnal hemoglobinuria Eur. J. Cardiothorac. Surg., March 1, 2004; 25(3): 468 - 470. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Mirsadraee, A. Fraser, M. A Kerr, T. E James, and C. van Doorn Inflammatory response in an immunosuppressed patient with Wegener's granulomatosis Perfusion, March 1, 2004; 19(2): 127 - 131. [Abstract] [PDF] |
||||
![]() |
P.-G. Chassot, P. van der Linden, M. Zaugg, X. M. Mueller, and D. R. Spahn Off-pump coronary artery bypass surgery: physiology and anaesthetic management{dagger} Br. J. Anaesth., March 1, 2004; 92(3): 400 - 413. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Racz, E. L. Hannan, O. W. Isom, V. A. Subramanian, R. H. Jones, J. P. Gold, T. J. Ryan, A. Hartman, A. T. Culliford, E. Bennett, et al. A comparison of short- and long-term outcomes after off-pump and on-pump coronary artery bypass graft surgery with sternotomy J. Am. Coll. Cardiol., February 18, 2004; 43(4): 557 - 564. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Gaudino, F. Glieca, F. Alessandrini, G. Nasso, C. Pragliola, N. Luciani, M. Morelli, and G. Possati High risk coronary artery bypass patient: incidence, surgical strategies, and results Ann. Thorac. Surg., February 1, 2004; 77(2): 574 - 579. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Athanasiou, S. Al-Ruzzeh, P. Kumar, M.-C. Crossman, M. Amrani, J. R. Pepper, R. Del Stanbridge, R. Casula, and B. Glenville Off-pump myocardial revascularization is associated with less incidence of stroke in elderly patients Ann. Thorac. Surg., February 1, 2004; 77(2): 745 - 753. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. B. Selvanayagam, S. E. Petersen, J. M. Francis, M. D. Robson, A. Kardos, S. Neubauer, and D. P. Taggart Effects of Off-Pump Versus On-Pump Coronary Surgery on Reversible and Irreversible Myocardial Injury: A Randomized Trial Using Cardiovascular Magnetic Resonance Imaging and Biochemical Markers Circulation, January 27, 2004; 109(3): 345 - 350. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. Wehlin, J. Vedin, J. Vaage, and J. Lundahl Activation of complement and leukocyte receptors during on- and off pump coronary artery bypass surgery Eur. J. Cardiothorac. Surg., January 1, 2004; 25(1): 35 - 42. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. M. Calafiore, M. Di Mauro, C. Canosa, G. Di Giammarco, A. L. Iaco, and M. Contini Myocardial revascularization with and without cardiopulmonary bypass: advantages, disadvantages and similarities Eur. J. Cardiothorac. Surg., December 1, 2003; 24(6): 953 - 960. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. L. Ngaage Off-pump coronary artery bypass grafting: the myth, the logic and the science Eur. J. Cardiothorac. Surg., October 1, 2003; 24(4): 557 - 570. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Gaudino, F. Andreotti, R. Zamparelli, A. Di Castelnuovo, G. Nasso, F. Burzotta, L. Iacoviello, M. B. Donati, R. Schiavello, A. Maseri, et al. The -174G/C Interleukin-6 Polymorphism Influences Postoperative Interleukin-6 Levels and Postoperative Atrial Fibrillation. Is Atrial Fibrillation an Inflammatory Complication? Circulation, September 9, 2003; 108(90101): II-195 - 199. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. El-Hamamsy, N. Durrleman, L.-M. Stevens, T. K. Leung, S. Theoret, M. Carrier, and L. P. Perrault Incidence and outcome of radial artery infections following cardiac surgery Ann. Thorac. Surg., September 1, 2003; 76(3): 801 - 804. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Biglioli, A. Cannata, F. Alamanni, M. Naliato, M. Porqueddu, M. Zanobini, E. Tremoli, and A. Parolari Biological effects of off-pump vs. on-pump coronary artery surgery: focus on inflammation, hemostasis and oxidative stress Eur. J. Cardiothorac. Surg., August 1, 2003; 24(2): 260 - 269. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. F. Immer, P. A. Berdat, A. S. Immer-Bansi, F. S. Eckstein, S. Muller, H. Saner, and T. P. Carrel Benefit to quality of life after Off-Pump versus On-Pump coronary bypass surgery Ann. Thorac. Surg., July 1, 2003; 76(1): 27 - 31. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Parolari, F. Alamanni, A. Cannata, M. Naliato, L. Bonati, P. Rubini, F. Veglia, E. Tremoli, and P. Biglioli Off-pump versus on-pump coronary artery bypass: meta-analysis of currently available randomized trials Ann. Thorac. Surg., July 1, 2003; 76(1): 37 - 40. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. J. Goldstein, R. B. Beauford, B. Luk, R. Karanam, T. Prendergast, F. Sardari, P. Burns, and C. Saunders Multivessel off-pump revascularization in patients with severe left ventricular dysfunction Eur. J. Cardiothorac. Surg., July 1, 2003; 24(1): 72 - 80. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Alhabash, A. Tirouvanziam, J.C. Roussel, and D. Duveau Early and 1 year angiographic evaluation of graft patency in off-pump coronary bypass surgery via sternotomy Interactive CardioVascular and Thoracic Surgery, June 1, 2003; 2(2): 149 - 153. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Ascione and G. D. Angelini Off-pump coronary artery bypass surgery: The implications of the evidence J. Thorac. Cardiovasc. Surg., April 1, 2003; 125(4): 779 - 781. [Full Text] [PDF] |
||||
![]() |
N. B. Aydin, H. Gercekoglu, B. Aksu, V. Ozkul, T. Sener, I. Kiygil, T. Turkoglu, S. Cimen, F. Babacan, and M. Demirtas Endotoxemia in coronary artery bypass surgery: A comparison of the off-pump technique and conventional cardiopulmonary bypass J. Thorac. Cardiovasc. Surg., April 1, 2003; 125(4): 843 - 848. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. H. Levy and K. A. Tanaka Inflammatory response to cardiopulmonary bypass Ann. Thorac. Surg., February 1, 2003; 75(2): S715 - 720. [Abstract] [Full Text] [PDF] |
||||
![]() |
R Ascione and G.D Angelini OPCAB surgery: a voyage of discovery back to the future Eur. Heart J., January 2, 2003; 24(2): 121 - 124. [Full Text] [PDF] |
||||
![]() |
M. Haase, A. Sharma, A. Fielitz, S. Uchino, J. Rocktaeschel, R. Bellomo, L. Doolan, G. Matalanis, A. Rosalion, B. F. Buxton, et al. On-pump coronary artery surgery versus off-pump exclusive arterial coronary grafting: a matched cohort comparison Ann. Thorac. Surg., January 1, 2003; 75(1): 62 - 67. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. G. Cerillo, L. Sabatino, S. Bevilacqua, P. A. Farneti, M. Scarlattini, F. Forini, and M. Glauber Nonthyroidal illness syndrome in off-pump coronary artery bypass grafting Ann. Thorac. Surg., January 1, 2003; 75(1): 82 - 87. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Ascione, M. Caputo, and G. D. Angelini Off-pump coronary artery bypass grafting: not a flash in the pan Ann. Thorac. Surg., January 1, 2003; 75(1): 306 - 313. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Menasche and L. H. Edmunds Jr. Extracorporeal Circulation: The Inflammatory Response Card. Surg. Adult, January 1, 2003; 2(2003): 349 - 360. [Full Text] |
||||
![]() |
M. Caputo, M. Yeatman, P. Narayan, G. Marchetto, R. Ascione, B. C. Reeves, and G. D. Angelini Effect of off-pump coronary surgery with right ventricular assist device on organ function and inflammatory response: a randomized controlled trial Ann. Thorac. Surg., December 1, 2002; 74(6): 2088 - 2095. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Wan and A. P. C. Yim Tai Ji: The law of inflammatory response J. Thorac. Cardiovasc. Surg., December 1, 2002; 124(6): 1071 - 1073. [Full Text] |
||||
![]() |
W. Y. Thong, A. G. Strickler, S. Li, E. E. Stewart, C. L. Collier, W. K. Vaughn, and N. A. Nussmeier Hyperthermia in the Forty-Eight Hours After Cardiopulmonary Bypass Anesth. Analg., December 1, 2002; 95(6): 1489 - 1495. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Fromes, D. Gaillard, O. Ponzio, M. Chauffert, M.-F. Gerhardt, P. Deleuze, and O. M. Bical Reduction of the inflammatory response following coronary bypass grafting with total minimal extracorporeal circulation Eur. J. Cardiothorac. Surg., October 1, 2002; 22(4): 527 - 533. [Abstract] [Full Text] [PDF] |
||||
![]() |
K.-B. Kim, K. R. Cho, W.-I. Chang, C. Lim, B. M. Ham, and Y. L. Kim Bilateral skeletonized internal thoracic artery graftings in off-pump coronary artery bypass: early result of Y versus in situ grafts Ann. Thorac. Surg., October 1, 2002; 74(4): S1371 - 1376. [Abstract] [Full Text] [PDF] |
||||
![]() |
K.-B. Kim, C. H. Kang, W.-I. Chang, C. Lim, J. H. Kim, B. M. Ham, and Y. L. Kim Off-pump coronary artery bypass with complete avoidance of aortic manipulation Ann. Thorac. Surg., October 1, 2002; 74(4): S1377 - 1382. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Ascione, B. C. Reeves, K. Rees, and G. D. Angelini Effectiveness of Coronary Artery Bypass Grafting With or Without Cardiopulmonary Bypass in Overweight Patients Circulation, October 1, 2002; 106(14): 1764 - 1770. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Franke, W. Lante, V. Fackeldey, H. P. Becker, C. Thode, W. D. Kuhlmann, and A. Markewitz Proinflammatory and antiinflammatory cytokines after cardiac operation: different cellular sources at different times Ann. Thorac. Surg., August 1, 2002; 74(2): 363 - 370. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Meyns, R. Autschbach, A. Boning, W. Konertz, K. Matschke, F. Schondube, K. Wiebe, and E. Fischer Coronary artery bypass grafting supported with intracardiac microaxial pumps versus normothermic cardiopulmonary bypass: a prospective randomized trial Eur. J. Cardiothorac. Surg., July 1, 2002; 22(1): 112 - 117. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Ascione, K. Rees, K. Santo, M.H. Chamberlain, G. Marchetto, F. Taylor, and G.D. Angelini Coronary artery bypass grafting in patients over 70 years old: the influence of age and surgical technique on early and mid-term clinical outcomes Eur. J. Cardiothorac. Surg., July 1, 2002; 22(1): 124 - 128. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Ascione, S. Al-Ruzzeh, K. Amer, and G. D Angelini Subsystem organ function during coronary surgery Perfusion, July 1, 2002; 17(4): 295 - 303. [Abstract] [PDF] |
||||
![]() |
M. H. Chamberlain, R. Ascione, B. C. Reeves, and G. D. Angelini Evaluation of the effectiveness of off-pump coronary artery bypass grafting in high-risk patients: an observational study Ann. Thorac. Surg., June 1, 2002; 73(6): 1866 - 1873. [Abstract] [Full Text] [PDF] |
||||
![]() |
R Dhillon, M Josen, M Henein, and A Redington Transcatheter closure of atrial septal defect preserves right ventricular function Heart, May 1, 2002; 87(5): 461 - 465. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. S.H. Ng, S. Wan, A. P.C. Yim, and A. A. Arifi Pulmonary Dysfunction After Cardiac Surgery* Chest, April 1, 2002; 121(4): 1269 - 1277. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. J O'Gara, V. Natarajan, K. Lilly, A. Husain, O. M Shapira, and R. J Shemin Clinical outcomes of on-pump coronary bypass using heparin-bonded circuits and reduced anti-coagulation compare favorably with off-pump approach Perfusion, March 1, 2002; 17(2): 91 - 94. [Abstract] [PDF] |
||||
![]() |
M. A. Chaney Corticosteroids and Cardiopulmonary Bypass : A Review of Clinical Investigations Chest, March 1, 2002; 121(3): 921 - 931. [Abstract] [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |