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René Prêtre
Qing Ye
Jurg Grünenfelder
Gregor Zund
Marko I. Turina
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Ann Thorac Surg 2000;69:51-55
© 2000 The Society of Thoracic Surgeons


Original Articles

Role of myocardial revascularization in postinfarction ventricular septal rupture

René Prêtre, MDa, Qing Ye, MDa, Jurg Grünenfelder, MDa, Gregor Zund, MDa, Marko I. Turina, MDa

a Clinic for Cardiovascular Surgery, University Hospital Zürich, Zürich, Switzerland

Address reprint requests to Dr Prêtre, Klinik für Herzgefässchirurgie, Universitätsspital, 100 Rämistrasse, 8091 Zürich, Switzerland
e-mail: rene.pretre{at}chi.usz.ch

Background. Postinfarction ventricular septal rupture requires urgent closure. The role of systematic coronarography and coronary revascularization needs clarification.

Methods. Fifty-four patients who underwent patch closure of postinfarction ventricular septal defect were reviewed. A coronarography had been systematically and myocardial revascularization selectively (when significant coronary artery stenosis existed) performed.

Results. No patient died or deteriorated during coronarography. Twenty-six patients showed no coronary artery disease besides the infarct-related artery, and 28 had associated disease. Threatened myocardial territories were revascularized usually with venous grafts (mean number of distal anastomosis, 2.5). Operative mortality was 19% and 32% (p = 0.36) and late mortality 43% and 53% (p = 0.75) in patients without and in patients with associated coronary artery disease, respectively. Survival curve in both group was similar, at least up to 8 years after operation.

Conclusions. Myocardial revascularization controlled the added risk of associated coronary artery disease in the postoperative period and in median term. A coronarography should be performed in all patients who can be stabilized hemodynamically and myocardial revascularization performed in case of significant stenosis.




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