ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Kagami Miyaji
Shinichi Takamoto
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Miyaji, K.
Right arrow Articles by Omata, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Miyaji, K.
Right arrow Articles by Omata, S.

Ann Thorac Surg 2000;69:151-155
© 2000 The Society of Thoracic Surgeons

Original Articles

Myocardial tactile stiffness during acute reduction of coronary blood flow

Kagami Miyaji, MDa, Seiryo Sugiura, MDb, Hirotaka Inaba, MDa, Shinichi Takamoto, MDa, Sadao Omata, PhDa

a Department of Cardiothoracic Surgery, University of Tokyo, Tokyo, Japan
b Second Department of Internal Medicine, University of Tokyo, Tokyo, Japan

Address reprint requests to Dr Miyaji, Department of Cardiothoracic Surgery, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan

Background. Evaluation of regional myocardial contractile function is of clinical importance. We have developed a new tactile sensor system for accurate measurement of myocardial stiffness in situ. We found that the myocardial stiffness measured by this sensor, which we call tactile stiffness, can be a very useful index for accurate quantification of regional myocardial function. In this study, we used a coronary stenosis model to investigate regional myocardial tactile stiffness under conditions of reduced coronary blood flow.

Methods. The myocardial tactile stiffness, coronary blood flow, and ventricular pressure and volume, of five open chest mongrel dogs weighing 15 to 17 kg, were measured. After measuring the baseline myocardial stiffness, coronary arterial stenosis was induced with a balloon occluder.

Results. Reducing the coronary flow to 50% and 25% of the baseline level reduced the end-systolic tactile stiffness significantly from 2.20 ± 0.16 g/mm2 to 2.05 ± 0.20 g/mm2 (p < 0.05) and from 2.21 ± 0.16 g/mm2 to 1.96 ± 0.18 g/mm2 (p < 0.01), respectively. Reducing the flow, to 50% and 25%, increased the end-diastolic stiffness significantly from 1.29 ± 0.15 g/mm2 to 1.39 ± 0.14 g/mm2 (p < 0.01) and from 1.30 ± 0.16 g/mm2 to 1.46 ± 0.14 g/mm2 (p < 0.05), respectively.

Conclusions. We consider that the regional myocardial tactile stiffness will be a useful index sensitive enough to detect changes in regional contractile function under conditions of reduced coronary blood flow.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2000 by The Society of Thoracic Surgeons.