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Ann Thorac Surg 1999;68:2376-2382
© 1999 The Society of Thoracic Surgeons

Current Reviews

Transmyocardial revascularization: the fate of myocardial channels

Peter Whittaker, PhDa

a Heart Institute, Good Samaritan Hospital and Department of Medicine, Cardiology Section, University of Southern California, Los Angeles, California, USA

Address reprint requests to Dr Whittaker, Heart Institute, Good Samaritan Hospital, 1225 Wilshire Blvd, Los Angeles, CA 90017-2395
e-mail: pwhittaker{at}dnamail.com

Attempted cardiac revascularization through laser-made channels has gained considerable recent notoriety. Although the treatment reduces angina, its ability to enhance perfusion is unclear, and the mechanism of action unknown. The fate of the channels appears an obvious place to look for insight. Therefore, this review focuses on temporal and spatial changes in channel morphology. An appreciation of the natural history of the channels not only has potential to elucidate mechanisms, but also to provide the basis for optimization of channel-making.




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