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Ann Thorac Surg 1999;68:1967-1970
© 1999 The Society of Thoracic Surgeons

II. Surgical Myocardial Protection

Protection of acutely ischemic myocardium by controlled reperfusion

Christian Schlensak, MDa, Torsten Doenst, MDa, Joseph Kobba, MDa, Friedhelm Beyersdorf, MDa

a Division of Cardiovascular Surgery, University of Freiburg, Freiburg, Germany

Address reprint requests to Dr Schlensak, Department of Cardiovascular Surgery, University of Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
e-mail: schlensa{at}ch11.ukl.uni-freiburg.de

Presented at the International Symposium on Myocardial Protection From Surgical Ischemic-Reperfusion Injury, Asheville, NC, Sep 21–24, 1997.

Abstract

The goal of revascularization after acute occlusion of a coronary artery is the return of contractile function and the reduction of mortality. Although reperfusion of ischemic myocardium is a prerequisite for return of function, it may, in itself, cause further injury. Controlled blood cardioplegic reperfusion reduces this "reperfusion injury" and provides maximal myocardial protection. In this article, we review recent advances in surgically controlled reperfusion and speculate on future prospects for myocardial protective techniques in patients with acute coronary artery occlusion.




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Eur. J. Cardiothorac. Surg., December 1, 2003; 24(6): 986 - 993.
[Abstract] [Full Text] [PDF]


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