ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Ralph A. Schmid
Walter Weder
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hamacher, J.
Right arrow Articles by Weder, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hamacher, J.
Right arrow Articles by Weder, W.

Ann Thorac Surg 1999;68:1792-1798
© 1999 The Society of Thoracic Surgeons

Original Articles

Two years’ outcome of lung volume reduction surgery in different morphologic emphysema types

Jürg Hamacher, MDa, Konrad E. Bloch, MDa, Uz Stammberger, MDb, Ralph A. Schmid, MDb, Irene Laube, MDa, Erich W. Russi, MDa, Walter Weder, MDb

a Pulmonary Division, Department of Internal Medicine, University Hospital, Zürich, Switzerland
b Division of Thoracic Surgery, Department of Surgery, University Hospital, Zürich, Switzerland

Address reprint requests to Dr Weder, Division of Thoracic Surgery, Department of Surgery, University Hospital, CH-8091 Zürich, Switzerland

Presented at the Thirty-fifth Annual Meeting of The Society of Thoracic Surgeons, San Antonio, TX, Jan 25–27, 1999.

Background. Lung volume reduction surgery (LVRS) improves dyspnea, pulmonary function, and quality of life in selected patients with severe emphysema. We investigated the role of emphysema morphology in 37 patients as an outcome predictor for up to 2 years after operation.

Methods. Patients selected for bilateral thoracoscopic LVRS were divided, according to a simplified emphysema morphology classification, into three groups (homogeneous, moderately heterogeneous, and markedly heterogeneous) based on a preoperative chest computed tomogram. Pulmonary function, walking distance, and dyspnea were assessed.

Results. Functional improvement after LVRS was best in markedly heterogeneous emphysema with an increase from preoperative forced expiratory volume in 1 second of 31% ± 2% (mean ± standard error of the mean) to 52% ± 4% of predicted postoperatively. It was significantly higher than in homogeneous emphysema (from 26% ± 1% to 38% ± 2% predicted) and in intermediately heterogeneous emphysema (from 29% ± 2% to 44% ± 45% predicted). At 24 months postoperatively, forced expiratory volume in 1 second and dyspnea score continued to be significantly better than preoperative levels in all three morphologic groups. The survival rate was highest in patients with markedly heterogeneous emphysema.

Conclusions. Functional and subjective improvements were maintained after LVRS for at least 24 months in patients with heterogeneous or homogeneous emphysema type.




This article has been cited by other articles:


Home page
 Proc Am Thorac SocHome page
E. P. Ingenito, D. E. Wood, and J. P. Utz
Bronchoscopic Lung Volume Reduction in Severe Emphysema
Proceedings of the ATS, May 1, 2008; 5(4): 454 - 460.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Tutic, K. E. Bloch, D. Lardinois, T. Brack, E. W. Russi, and W. Weder
Long-term results after lung volume reduction surgery in patients with {alpha}1-antitrypsin deficiency
J. Thorac. Cardiovasc. Surg., September 1, 2004; 128(3): 408 - 413.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
R. M. Kaplan, A. L. Ries, J. Reilly, and Z. Mohsenifar
Measurement of Health-Related Quality of Life in the National Emphysema Treatment Trial
Chest, September 1, 2004; 126(3): 781 - 789.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Decramer
Treatment of chronic respiratory failure: lung volume reduction surgery versus rehabilitation
Eur. Respir. J., November 16, 2003; 22(47_suppl): 47S - 56s.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
E.W. Russi, K.E. Bloch, and W. Weder
Lung volume reduction surgery: what can we learn from the National Emphysema Treatment Trial?
Eur. Respir. J., October 1, 2003; 22(4): 571 - 573.
[Full Text] [PDF]

Home page
 ChestHome page
A. F. Gelb and R. J. McKenna Jr
Lung Volume Reduction Surgery Update
Chest, April 1, 2003; 123(4): 975 - 977.
[Full Text] [PDF]

Home page
 ChestHome page
K. Cederlund, U. Tylen, L. Jorfeldt, and P. Aspelin
Classification of Emphysema in Candidates for Lung Volume Reduction Surgery* : A New Objective and Surgically Oriented Model for Describing CT Severity and Heterogeneity
Chest, August 1, 2002; 122(2): 590 - 596.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
K. E. Bloch, C. L. Georgescu, E. W. Russi, and W. Weder
Gain and subsequent loss of lung function after lung volume reduction surgery in cases of severe emphysema with different morphologic patterns
J. Thorac. Cardiovasc. Surg., May 1, 2002; 123(5): 845 - 854.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
M. Brenner, X. Gonzalez, B. Jones, R. Ha, K. Osann, R. McKenna, and J. Milliken
Effects of a Novel Implantable Elastomer Device for Lung Volume Reduction Surgery in a Rabbit Model of Elastase-Induced Emphysema
Chest, January 1, 2002; 121(1): 201 - 209.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
Patients at High Risk of Death after Lung-Volume-Reduction Surgery
N. Engl. J. Med., October 11, 2001; 345(15): 1075 - 1083.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. L. Berger, B. R. Celli, A. L. Meneghetti, P. H. Bagley, C. D. Wright, E. P. Ingenito, A. Gray, and G. L. Snider
Limitations of randomized clinical trials for evaluating emerging operations: the case of lung volume reduction surgery
Ann. Thorac. Surg., August 1, 2001; 72(2): 649 - 657.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. F. GELB, R. J. McKENNA Jr., M. BRENNER, J. D. EPSTEIN, and N. ZAMEL
Lung Function 5 yr after Lung Volume Reduction Surgery for Emphysema
Am. J. Respir. Crit. Care Med., June 1, 2001; 163(7): 1562 - 1566.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
A. F. Gelb, R. J. McKenna Jr, and M. Brenner
Expanding Knowledge of Lung Volume Reduction
Chest, May 1, 2001; 119(5): 1300 - 1303.
[Full Text] [PDF]

Home page
 ChestHome page
K. R. Flaherty, E. A. Kazerooni, J. L. Curtis, M. Iannettoni, L. Lange, M. A. Schork, and F. J. Martinez
Short-term and Long-term Outcomes After Bilateral Lung Volume Reduction Surgery : Prediction by Quantitative CT
Chest, May 1, 2001; 119(5): 1337 - 1346.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
U. Stammberger, W. Klepetko, G. Stamatis, J. Hamacher, R. A. Schmid, W. Wisser, L. Hillerjan, and W. Weder
Buttressing the staple line in lung volume reduction surgery: a randomized three-center study
Ann. Thorac. Surg., December 1, 2000; 70(6): 1820 - 1825.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
U. Stammberger, R. Thurnheer, R. A. Schmid, E. W. Russi, and W. Weder
Redo lung volume reduction surgery in a patient with {alpha}1-antitrypsin deficiency
Ann. Thorac. Surg., February 1, 2000; 69(2): 632 - 633.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1999 by The Society of Thoracic Surgeons.