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A. Marc Gillinov
Delos M. Cosgrove, III
Bruce W. Lytle
Nicholas G. Smedira
Patrick M. McCarthy
Joseph F. Sabik
Eugene H. Blackstone
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Ann Thorac Surg 1999;68:820-824
© 1999 The Society of Thoracic Surgeons


Original Articles: Cardiovascular

Is anterior leaflet repair always necessary in repair of bileaflet mitral valve prolapse?

A. Marc Gillinov, MDa, Delos M. Cosgrove, III, MDa, Sudhir Wahi, MDa, William J. Stewart, MDa, Bruce W. Lytle, MDa, Nicholas G. Smedira, MDa, Patrick M. McCarthy, MDa, Per N. Wierup, MDa, Joseph F. Sabik, MDa, Eugene H. Blackstone, MDa

a Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

Address reprint requests to Dr Gillinov, Department of Thoracic and Cardiovascular Surgery/F25, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195
e-mail: gillinom{at}cesmtp.ccf.org

Presented at the Thirty-fifth Annual Meeting of The Society of Thoracic Surgeons, San Antonio, TX, Jan 25–27, 1999.

Background. Traditionally, bileaflet prolapse has been treated by posterior leaflet resection combined with one of a number of procedures designed to support the anterior leaflet. However, most patients with bileaflet prolapse do not have important anterior chordal pathology. This study was undertaken to evaluate the effectiveness of a strategy of posterior leaflet resection and annuloplasty alone for patients with bileaflet prolapse and no anterior chordal rupture or severe anterior chordal elongation.

Methods. From 1993 to 1997, 93 patients with transesophageal echocardiography (TEE) demonstrated bileaflet prolapse and without anterior chordal rupture or important anterior chordal elongation had primary isolated mitral valve repair consisting only of posterior leaflet resection (quadrangular in 28 and sliding in 65) and annuloplasty (Cosgrove-Edwards in 83, pericardial in 9, and Carpentier-Edwards in 1). All patients had severe mitral regurgitation documented by intraoperative TEE. Mean age was 55 ± 13 years; 60% were men.

Results. Postrepair, mitral regurgitation was 0 to trace in 93% and 1+ in 7%. There were no operative deaths. Late follow-up was available in all patients, with 277 patient-years of follow-up available for analysis. Five-year actuarial survival was 95%. At a mean interval of 2.3 ± 1.3 (SD) years, echocardiography demonstrated no or trace mitral regurgitation in 65%, 1+ in 28%, and 2+ in 7%. No correlates of late mitral regurgitation were identified by multivariable analysis. No patient has required reoperation.

Conclusions. In the absence of significant anterior chordal pathology, a strategy of posterior leaflet resection and annuloplasty corrects anterior leaflet prolapse and mitral regurgitation, and provides a durable repair without the necessity of additional procedures on the anterior leaflet.




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