|
|
||||||||
Ann Thorac Surg 1999;68:188-193
© 1999 The Society of Thoracic Surgeons
a Thoracic Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
Address reprint requests to Dr Downey, Division of Thoracic Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021
e-mail: downeyr{at}mskcc.org
Presented at the Forty-fifth Annual Meeting of the Southern Thoracic Surgical Association, Orlando, FL, Nov 1214, 1998.
Background. The long-term survival after operation of patients with lung cancer involving the chest wall is known to be related to regional nodal involvement and completeness of resection, but it is not known whether the depth of chest wall involvement or the type of resection (extrapleural or en bloc) affects either the rate of local recurrence or survival.
Methods. We retrospectively reviewed the Memorial Sloan-Kettering Cancer Center experience between 1974 and 1993 of 334 patients undergoing surgical exploration for lung cancer involving the chest wall or parietal pleura.
Results. Of 334 patients who underwent exploration, 175 had apparently complete (R0) resections, 94 had incomplete (R1 or R2) resections, and 65 underwent exploration without resection. The overall 5-year survival of R0 patients was 32%, of R1 or R2 patients 4%, and of patients undergoing exploration without resection 0%. In the patients undergoing R0 resections, the extent of chest wall involvement was limited to the parietal pleura in 80 patients, and extended into the ribs or soft tissues in 95. The 5-year survival of R0 patients with T3 N0 M0 disease was 49%, T3 N1 M0 disease 27%, and T3 N2 M0 disease 15% (p < 0.0003). Independent of lymph node involvement, a survival advantage was observed in R0 patients if the chest wall involvement was limited to parietal pleura only, rather than invading into the chest wall musculature or ribs.
Conclusions. Survival of patients with lung cancer invading the chest wall after resection with curative intent is highly dependent on the extent of nodal involvement and the completeness of resection, and much less so on the depth of chest wall invasion.
This article has been cited by other articles:
![]() |
E. Stoelben and C. Ludwig Chest wall resection for lung cancer: indications and techniques Eur. J. Cardiothorac. Surg., March 1, 2009; 35(3): 450 - 456. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Sakakura, S. Mori, F. Ishiguro, T. Fukui, S. Hatooka, M. Shinoda, K. Yokoi, and T. Mitsudomi Subcategorization of Resectable Non-Small Cell Lung Cancer Involving Neighboring Structures Ann. Thorac. Surg., October 1, 2008; 86(4): 1076 - 1083. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. Bandi, W. Lunn, A. Ernst, R. Eberhardt, H. Hoffmann, and F. J. F. Herth Ultrasound vs CT in Detecting Chest Wall Invasion by Tumor: A Prospective Study Chest, April 1, 2008; 133(4): 881 - 886. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. R. Shen, B. F. Meyers, J. M. Larner, and D. R. Jones Special Treatment Issues in Lung Cancer: ACCP Evidence-Based Clinical Practice Guidelines (2nd Edition) Chest, September 1, 2007; 132(3_suppl): 290S - 305S. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. C. Mineo, V. Ambrogi, E. Pompeo, and A. Baldi Immunohistochemistry-detected microscopic tumor spread affects outcome in en-bloc resection for T3-chest wall lung cancer Eur. J. Cardiothorac. Surg., June 1, 2007; 31(6): 1120 - 1124. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Doddoli, B. D'Journo, F. Le Pimpec-Barthes, A. Dujon, C. Foucault, P. Thomas, and M. Riquet Lung Cancer Invading the Chest Wall: A Plea for En-Bloc Resection but the Need for New Treatment Strategies Ann. Thorac. Surg., December 1, 2005; 80(6): 2032 - 2040. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. A. DiPerna and D. E. Wood Surgical Management of T3 and T4 Lung Cancer Clin. Cancer Res., July 1, 2005; 11(13): 5038s - 5044s. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Matsuoka, W. Nishio, M. Okada, T. Sakamoto, M. Yoshimura, and N. Tsubota Resection of chest wall invasion in patients with non-small cell lung cancer Eur. J. Cardiothorac. Surg., December 1, 2004; 26(6): 1200 - 1204. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. J Podbielski, R. A Issa, J.-P. Fontaine, and H. E Rodriguez Thoracoscopic Transillumination in Chest Wall Resection Asian Cardiovasc Thorac Ann, June 1, 2004; 12(2): 171 - 172. [Abstract] [Full Text] [PDF] |
||||
![]() |
C.K. Connolly, P.E.Y. Van Schil, R. Milroy, O. Braendli, and R.J. Prescott The approach to the surgical management of cancer in four European countries Eur. Respir. J., November 1, 2003; 22(5): 838 - 844. [Abstract] [Full Text] [PDF] |
||||
![]() |
A.E. Martin-Ucar, R. Nicum, I. Oey, J.G. Edwards, and D.A. Waller En-bloc chest wall and lung resection for non-small cell lung cancer. Predictors of 60-day non-cancer related mortality Eur. J. Cardiothorac. Surg., June 1, 2003; 23(6): 859 - 864. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Karmy-Jones and E. Vallieres Non-small Cell Lung Cancer With Chest Wall Involvement Chest, May 1, 2003; 123(5): 1323 - 1325. [Full Text] [PDF] |
||||
![]() |
G. Roviaro, F. Varoli, F. Grignani, C. Vergani, C. Pagano, M. Maciocco, and A. Romanelli Non-small Cell Lung Cancer With Chest Wall Invasion: Evolution of Surgical Treatment and Prognosis in the Last 3 Decades Chest, May 1, 2003; 123(5): 1341 - 1347. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. J. Scott, J. Howington, and B. Movsas Treatment of Stage II Non-small Cell Lung Cancer Chest, January 1, 2003; 123 (2009): 188S - 201S. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Akay, A. K. Cangir, H. Kutlay, S. Kavukcu, I. Okten, and S. Yavuzer Surgical treatment of peripheral lung cancer adherent to the parietal pleura Eur. J. Cardiothorac. Surg., October 1, 2002; 22(4): 615 - 620. [Abstract] [Full Text] [PDF] |
||||
![]() |
H.S. Hofmann, C. Taege, C. Lautenschlager, H. Neef, and R.E. Silber Microscopic (R1) and macroscopic (R2) residual disease in patients with resected non-small cell lung cancer Eur. J. Cardiothorac. Surg., April 1, 2002; 21(4): 606 - 610. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. M. Burkhart, M. S. Allen, F. C. Nichols III, C. Deschamps, D. L. Miller, V. F. Trastek, and P. C. Pairolero Results of en bloc resection for bronchogenic carcinoma with chest wall invasion J. Thorac. Cardiovasc. Surg., April 1, 2002; 123(4): 670 - 675. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Riquet, L. Lang-Lazdunski, F. Le Pimpec-Barthes, A. Dujon, R. Souilamas, C. Danel, and D. Manac'h Characteristics and prognosis of resected T3 non-small cell lung cancer Ann. Thorac. Surg., January 1, 2002; 73(1): 253 - 258. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Elia, S. Griffo, M. Gentile, R. Costabile, and G. Ferrante Surgical treatment of lung cancer invading chest wall: a retrospective analysis of 110 patients Eur. J. Cardiothorac. Surg., August 1, 2001; 20(2): 356 - 360. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Facciolo, G. Cardillo, M. Lopergolo, G. Pallone, F. Sera, and M. Martelli Chest wall invasion in non-small cell lung carcinoma: A rationale for en bloc resection J. Thorac. Cardiovasc. Surg., April 1, 2001; 121(4): 649 - 656. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Magdeleinat, M. Alifano, C. Benbrahem, L. Spaggiari, C. Porrello, P. Puyo, P. Levasseur, and J. F. Regnard Surgical treatment of lung cancer invading the chest wall: results and prognostic factors Ann. Thorac. Surg., April 1, 2001; 71(4): 1094 - 1099. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. D. Widmann, R. J. Caccavale, J.-P. Bocage, and R. J. Lewis Video-assisted thoracic surgery resection of chest wall en bloc for lung carcinoma Ann. Thorac. Surg., December 1, 2000; 70(6): 2138 - 2140. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Yokoi, R. Tsuchiya, T. Mori, K. Nagai, T. Furukawa, S. Fujimura, K. Nakagawa, and Y. Ichinose Results of surgical treatment of lung cancer involving the diaphragm J. Thorac. Cardiovasc. Surg., October 1, 2000; 120(4): 799 - 805. [Abstract] [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |