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Ann Thorac Surg 1999;67:1785-1787
© 1999 The Society of Thoracic Surgeons

Case Reports

Successful thrombolysis for massive pulmonary embolism after pulmonary resection

Rana A. Sayeed, FRCSa, Samer A.M. Nashef, FRCSa

a Cardiothoracic Surgical Unit, Papworth Hospital, Cambridge, United Kingdom

Accepted for publication November 16, 1998.

Address reprint requests to Mr Nashef, Cardiothoracic Surgical Unit, Papworth Hospital, Papworth Everard, Cambridge CB3 8RE, UK

We report the successful use of thrombolysis for acute massive pulmonary embolism 2 days after right lower lobectomy for bronchial adenocarcinoma. Pulmonary angiography revealed extensive clot unsuitable for surgical embolectomy. A bolus infusion of recombinant tissue plasminogen activator produced an immediate improvement in the patient’s hemodynamic state. There was substantial blood loss requiring the transfusion of 21 units of blood over the postoperative period. The patient made a successful recovery and remained well at 1 year.




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