| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 1999;67:1370-1375
© 1999 The Society of Thoracic Surgeons
a Thoraxcenter, University Hospital of Groningen, Groningen, the Netherlands
Accepted for publication December 3, 1998.
Address reprint requests to Dr Mariani, Thoraxcenter, University Hospital Groningen, Hanzeplein, 1, PO Box 30.001, 9700 RB Groningen, the Netherlands
e-mail: M.Mariani{at}thorax.azg.nl
Background. Hemostasis is preserved after off-pump coronary operations compared with conventional coronary procedures. However, this preserved hemostasis may result in a procoagulant activity.
Methods. We prospectively studied coagulation in 22 patients who underwent off-pump coronary operation either through a midline sternotomy (n = 14) or with minimally invasive anterolateral thoracotomy (n = 8).
Results. Procoagulant activity, represented by prothrombin factor 1 and 2, remained at baseline levels during operation but increased significantly on postoperative day 1. Factor VII remained at baseline levels during the operation but decreased significantly on postoperative day 1. Fibrinolysis was increased as indicated by the fibrin degradation products on postoperative day 1. A promoted hemostasis attributable to endothelial activation was indicated by the increase in von Willebrand factor on postoperative day 1. Platelets counts and platelet activation (ß-thromboglobulin) remained at baseline levels after the operation. No adverse clinical events occurred.
Conclusions. Patients undergoing off-pump coronary operation show an increased procoagulant activity in the first postoperative 24 hours regardless of the surgical approach (midline sternotomy or anterolateral thoracotomy). This procoagulant activity is not mediated by platelet-related factors. Therefore, a specific perioperative prophylactic pharmacologic regimen is advisable.
This article has been cited by other articles:
|
|
 |
|
  K.-B. Kim, J. S. Kim, H.-J. Kang, B.-K. Koo, H.-S. Kim, B.-H. Oh, and Y.-B. Park Ten-year experience with off-pump coronary artery bypass grafting: Lessons learned from early postoperative angiography J. Thorac. Cardiovasc. Surg., February 1, 2010; 139(2): 256 - 262. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. H. Kim, C. Daskalakis, S. C. Silvestry, M. P. Sheth, A. N. Lee, S. Adams, S. Hohmann, S. Medvedev, and D. J. Whellan Aspirin and clopidogrel use in the early postoperative period following on-pump and off-pump coronary artery bypass grafting. J. Thorac. Cardiovasc. Surg., December 1, 2009; 138(6): 1377 - 1384. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. B. Halbersma, S. C. Arrigoni, G. Mecozzi, J. G. Grandjean, A. P. Kappetein, J. van der Palen, F. Zijlstra, and M. A. Mariani Four-year outcome of OPCAB no-touch with total arterial Y-graft: making the best treatment a daily practice. Ann. Thorac. Surg., September 1, 2009; 88(3): 796 - 801. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Shimokawa, S. Manabe, T. Sawada, S. Matsuyama, T. Fukui, and S. Takanashi Intermediate-term patency of saphenous vein graft with a clampless hand-sewn proximal anastomosis device after off-pump coronary bypass grafting. Ann. Thorac. Surg., May 1, 2009; 87(5): 1416 - 1420. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ranucci, A. Balduini, A. Ditta, A. Boncilli, and S. Brozzi A Systematic Review of Biocompatible Cardiopulmonary Bypass Circuits and Clinical Outcome Ann. Thorac. Surg., April 1, 2009; 87(4): 1311 - 1319. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Jervis, V. Senthilnathan, and A. B. Lerner Management of a Patient with Lupus Anticoagulant and Antiphospholipid Syndrome for Off-Pump Coronary Artery Bypass Grafting Using the Hepcon(R) System Anesth. Analg., April 1, 2009; 108(4): 1116 - 1119. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Bednar, P. Osmancik, T. Vanek, H. Mocikova, M. Jares, Z. Straka, and P. Widimsky Platelet activity and aspirin efficacy after off-pump compared with on-pump coronary artery bypass surgery: results from the prospective randomized trial PRAGUE 11-Coronary Artery Bypass and REactivity of Thrombocytes (CABARET). J. Thorac. Cardiovasc. Surg., October 1, 2008; 136(4): 1054 - 1060. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Briffa Off pump coronary artery bypass: a passing fad or ready for prime time? Eur. Heart J., June 1, 2008; 29(11): 1346 - 1349. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. R. Untch, W. P. Jeske, J. Schwartz, S. Botkin, M. Prechel, J. M. Walenga, and M. Bakhos Inflammatory and Hemostatic Activation in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting Clinical and Applied Thrombosis/Hemostasis, April 1, 2008; 14(2): 141 - 148. [Abstract] [PDF]
|
|
|
|
|
|
K.-B. Kim, K. R. Cho, and D. S. Jeong Midterm angiographic follow-up after off-pump coronary artery bypass: serial comparison using early, 1-year, and 5-year postoperative angiograms. J. Thorac. Cardiovasc. Surg., February 1, 2008; 135(2): 300 - 307. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. R. Cho, D. S. Jeong, and K.-B. Kim Influence of vein graft use on postoperative 1-year results after off-pump coronary artery bypass surgery Eur. J. Cardiothorac. Surg., November 1, 2007; 32(5): 718 - 723. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. K. Shim, Y. S. Choi, Y. J. Oh, S. O. Bang, K. J. Yoo, and Y. L. Kwak Effects of preoperative aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypass graft surgery J. Thorac. Cardiovasc. Surg., July 1, 2007; 134(1): 59 - 64. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Ballotta, H. Z. Saleh, H. W. El Baghdady, M. Gomaa, F. Belloli, H. Kandil, Y. Balbaa, F. Bettini, E. Bossone, L. Menicanti, et al. Comparison of early platelet activation in patients undergoing on-pump versus off-pump coronary artery bypass surgery J. Thorac. Cardiovasc. Surg., July 1, 2007; 134(1): 132 - 138. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. N. Hoel, V. Videm, T. E. Mollnes, K. Saatvedt, F. Brosstad, A. E. Fiane, E. Fosse, and J. L. Svennevig Off-pump cardiac surgery abolishes complement activation Perfusion, July 1, 2007; 22(4): 251 - 256. [Abstract] [PDF]
|
|
|
|
 |
|
 A. T Gurbuz, O. Findik, H. Cui, and A. Aytac Radial Artery Graft Use and Off-Pump Coronary Artery Bypass Surgery Outcome Asian Cardiovasc Thorac Ann, April 1, 2007; 15(2): 106 - 112. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Novitzky, A L. Shroyer, J. F Collins, G. O McDonald, J. Lucke, B. Hattler, E. Kozora, D. D Bradham, J. Baltz, F. L Grover, et al. A study design to assess the safety and efficacy of on-pump versus off-pump coronary bypass grafting: the ROOBY trial Clinical Trials, February 1, 2007; 4(1): 81 - 91. [Abstract] [PDF]
|
|
|
|
 |
|
 A. Ben Ari, E. Elinav, A. Elami, and I. Matot Off-pump coronary artery bypass grafting in a patient with Child class C liver cirrhosis awaiting liver transplantation Br. J. Anaesth., October 1, 2006; 97(4): 468 - 472. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Al-Ruzzeh, S. George, M. Bustami, J. Wray, C. Ilsley, T. Athanasiou, and M. Amrani Effect of off-pump coronary artery bypass surgery on clinical, angiographic, neurocognitive, and quality of life outcomes: randomised controlled trial BMJ, June 10, 2006; 332(7554): 1365. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. E. Halkos, W. A. Cooper, R. Petersen, J. D. Puskas, O. M. Lattouf, J. M. Craver, and R. A. Guyton Early Administration of Clopidogrel Is Safe After Off-Pump Coronary Artery Bypass Surgery Ann. Thorac. Surg., March 1, 2006; 81(3): 815 - 819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. T. Gurbuz, A. A. Zia, A. C. Vuran, H. Cui, and A. Aytac Postoperative clopidogrel improves mid-term outcome after off-pump coronary artery bypass graft surgery: a prospective study Eur. J. Cardiothorac. Surg., February 1, 2006; 29(2): 190 - 195. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Paparella, A. Galeone, M. T. Venneri, M. Coviello, G. Scrascia, N. Marraudino, M. Quaranta, L. de Luca Tupputi Schinosa, and S. J. Brister Activation of the coagulation system during coronary artery bypass grafting: Comparison between on-pump and off-pump techniques J. Thorac. Cardiovasc. Surg., February 1, 2006; 131(2): 290 - 297. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. S. Poston, C. White, J. Gu, J. Brown, J. Gammie, R. N. Pierson, A. Lee, I. Connerney, T. Avari, R. Christenson, et al. Aprotinin Shows Both Hemostatic and Antithrombotic Effects During Off-Pump Coronary Artery Bypass Grafting Ann. Thorac. Surg., January 1, 2006; 81(1): 104 - 111. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Vanek, M. Jares, R. Fajt, Z. Straka, K. Jirasek, M. Kolesar, P. Brucek, and M. Maly Fibrinolytic inhibitors in off-pump coronary surgery: a prospective, randomized, double-blind TAP study (tranexamic acid, aprotinin, placebo) Eur. J. Cardiothorac. Surg., October 1, 2005; 28(4): 563 - 568. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Vedin, A. Antovic, A. Ericsson, and J. Vaage Hemostasis in Off-Pump Compared to On-Pump Coronary Artery Bypass Grafting: A Prospective, Randomized Study Ann. Thorac. Surg., August 1, 2005; 80(2): 586 - 593. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Dixon, J. Santamaria, and D. Campbell Coagulation Activation and Organ Dysfunction Following Cardiac Surgery Chest, July 1, 2005; 128(1): 229 - 236. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Poston, J. Gu, J. Manchio, A. Lee, J. Brown, J. Gammie, C. White, and B. P. Griffith Platelet function tests predict bleeding and thrombotic events after off-pump coronary bypass grafting Eur. J. Cardiothorac. Surg., April 1, 2005; 27(4): 584 - 591. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Zimmermann, M. Kurt, A. Wenk, J. Winter, E. Gams, and T. Hohlfeld Is cardiopulmonary bypass a reason for aspirin resistance after coronary artery bypass grafting? Eur. J. Cardiothorac. Surg., April 1, 2005; 27(4): 606 - 610. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Pepper Controversies in Off-pump Coronary Artery Surgery Clin. Med. Res., February 1, 2005; 3(1): 27 - 33. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. G Raja, Z. Haider, and H. Zaman Off-Pump Coronary Artery Bypass Surgery: Analysis of 5-Year Experience Asian Cardiovasc Thorac Ann, December 1, 2004; 12(4): 306 - 311. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. W. Boonstra and W. van Oeveren Clopidogrel and Postoperative Bleeding Ann. Thorac. Surg., November 1, 2004; 78(5): 1522 - 1522. [Full Text] [PDF]
|
|
|
|
|
|
M. A. Mariani, A. D'Alfonso, and J. G. Grandjean Total Arterial Off-Pump Coronary Surgery: Time to Change Our Habits? Ann. Thorac. Surg., November 1, 2004; 78(5): 1591 - 1597. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Lo, R. Fijnheer, D. Castigliego, C. Borst, C. J. Kalkman, and A. P. Nierich Activation of Hemostasis After Coronary Artery Bypass Grafting With or Without Cardiopulmonary Bypass Anesth. Analg., September 1, 2004; 99(3): 634 - 640. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Englberger, F. F. Immer, F. S. Eckstein, P. A. Berdat, A. Haeberli, and T. P. Carrel Off-Pump coronary artery bypass operation does not increase procoagulant and fibrinolytic activity: preliminary results Ann. Thorac. Surg., May 1, 2004; 77(5): 1560 - 1566. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Casati, S. Benussi, L. Sandrelli, M. A. Grasso, S. Spagnolo, and A. D'Angelo Intraoperative Moderate Acute Normovolemic Hemodilution Associated with a Comprehensive Blood-Sparing Protocol in Off-Pump Coronary Surgery Anesth. Analg., May 1, 2004; 98(5): 1217 - 1223. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. Puskas, W. H. Williams, E. M. Mahoney, P. R. Huber, P. C. Block, P. G. Duke, J. R. Staples, K. E. Glas, J. J. Marshall, M. E. Leimbach, et al. Off-Pump vs Conventional Coronary Artery Bypass Grafting: Early and 1-Year Graft Patency, Cost, and Quality-of-Life Outcomes: A Randomized Trial JAMA, April 21, 2004; 291(15): 1841 - 1849. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. B. Hangler, K. Pfaller, E. Ruttmann, D. Hoefer, T. Schachner, G. Laufer, and H. Antretter Effects of intracoronary shunts on coronary endothelial coating in the human beating heart Ann. Thorac. Surg., March 1, 2004; 77(3): 776 - 780. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. F. Merry, P. J. Raudkivi, N. G. Middleton, J. M. McDougall, P. Nand, B. P. Mills, B. J. Webber, C. M. Frampton, and H. D. White Bivalirudin versus heparin and protamine in off-pump coronary artery bypass surgery Ann. Thorac. Surg., March 1, 2004; 77(3): 925 - 931. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P.-G. Chassot, P. van der Linden, M. Zaugg, X. M. Mueller, and D. R. Spahn Off-pump coronary artery bypass surgery: physiology and anaesthetic management{dagger} Br. J. Anaesth., March 1, 2004; 92(3): 400 - 413. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Biglioli, A. Cannata, F. Alamanni, M. Naliato, M. Porqueddu, M. Zanobini, E. Tremoli, and A. Parolari Biological effects of off-pump vs. on-pump coronary artery surgery: focus on inflammation, hemostasis and oxidative stress Eur. J. Cardiothorac. Surg., August 1, 2003; 24(2): 260 - 269. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. A. Kurlansky Is there a hypercoagulable state after off-pump coronary artery bypass surgery? What do we know and what can we do? J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 7 - 10. [Full Text] [PDF]
|
|
|
|
|
|
H. Y. Karagoz, M. Kurtoglu, B. Bakkaloglu, B. Sonmez, T. Cetintas, and K. Bayazit Coronary artery bypass grafting in the awake patient: Three years' experience in 137 patients J. Thorac. Cardiovasc. Surg., June 1, 2003; 125(6): 1401 - 1404. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. Levy and K. A. Tanaka Inflammatory response to cardiopulmonary bypass Ann. Thorac. Surg., February 1, 2003; 75(2): S715 - 720. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. M. Dewey and M. J. Mack Myocardial Revascularization Without Cardiopulmonary Bypass Card. Surg. Adult, January 1, 2003; 2(2003): 609 - 625. [Full Text]
|
|
|
|
|
|
C. Baufreton, J. L. de Brux, P. Binuani, J.-J. Corbeau, J. B. Subayi, J. C. Daniel, and P. Treanor A combined approach for improving cardiopulmonary bypass in coronary artery surgery: a pilot study Perfusion, December 1, 2002; 17(6): 407 - 413. [Abstract] [PDF]
|
|
|
|
|
|
L. Englberger, P. Markart, F.S. Eckstein, F.F. Immer, P.A. Berdat, and T.P. Carrel Aprotinin reduces blood loss in off-pump coronary artery bypass (OPCAB) surgery Eur. J. Cardiothorac. Surg., October 1, 2002; 22(4): 545 - 551. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K.-B. Kim, K. R. Cho, W.-I. Chang, C. Lim, B. M. Ham, and Y. L. Kim Bilateral skeletonized internal thoracic artery graftings in off-pump coronary artery bypass: early result of Y versus in situ grafts Ann. Thorac. Surg., October 1, 2002; 74(4): S1371 - 1376. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R L Quigley, D W Fried, R Salenger, J Pym, and R Y Highbloom Thrombelastographic changes in OPCAB surgical patients Perfusion, September 1, 2002; 17(5): 363 - 367. [Abstract] [PDF]
|
|
|
|
|
|
R. G. Demaria, S. Fortier, and L. P. Perrault Coronary endothelial damage during off-pump CABG related to coronary-clamping and gas insufflation Eur. J. Cardiothorac. Surg., December 1, 2001; 20(6): 1270 - 1271. [Full Text] [PDF]
|
|
|
|
|
|
Y. Okazaki, K. Takarabe, and T. Itoh Reply to Demaria et al. Eur. J. Cardiothorac. Surg., December 1, 2001; 20(6): 1272 - 1272. [Full Text] [PDF]
|
|
|
|
 |
|
 M. Capdeville and J. H. Lee Off-Pump Coronary Artery Bypass Surgery: Revival of an Old Technique Seminars in Cardiothoracic and Vascular Anesthesia, November 1, 2001; 5(4): 345 - 361. [Abstract] [PDF]
|
|
|
|
|
|
K.-B. Kim, C. Lim, C. Lee, I.-H. Chae, B.-H. Oh, M.-M. Lee, and Y.-B. Park Off-pump coronary artery bypass may decrease the patency of saphenous vein grafts Ann. Thorac. Surg., September 1, 2001; 72(3): S1033 - 1037. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Casati, C. Gerli, A. Franco, G. Torri, A. D'Angelo, S. Benussi, and O. Alfieri Tranexamic acid in off-pump coronary surgery: a preliminary, randomized, double-blind, placebo-controlled study Ann. Thorac. Surg., August 1, 2001; 72(2): 470 - 475. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. B. Hangler, K. Pfaller, H. Antretter, O. E. Dapunt, and J. O. Bonatti Coronary endothelial injury after local occlusion on the human beating heart Ann. Thorac. Surg., January 1, 2001; 71(1): 122 - 127. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Y. Karagoz, B. Sonmez, B. Bakkaloglu, M. Kurtoglu, M. Erdinc, A. Turkeli, and K. Bayazit Coronary artery bypass grafting in the conscious patient without endotracheal general anesthesia Ann. Thorac. Surg., July 1, 2000; 70(1): 91 - 96. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
