ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Matsuzaki, Y.
Right arrow Articles by Onitsuka, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Matsuzaki, Y.
Right arrow Articles by Onitsuka, T.

Ann Thorac Surg 1999;67:908-910
© 1999 The Society of Thoracic Surgeons

Original Articles

Beneficial effect of prostaglandin E1 on blood flow to the gastric tube after esophagectomy

Yasunori Matsuzaki, MDa, Masao Edagawa, MDa, Masayuki Maeda, MDa, Tetsuya Shimizu, MDa, Ryo Sekiya, MDa, Kunihide Nakamura, MDa, Toshio Onitsuka, MD, PhDa

a Department of Surgery II, Miyazaki Medical College, Miyazaki, Japan

Accepted for publication September 25, 1998.

Address reprint requests to Dr Matsuzaki, Department of Surgery II, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan

Background. A prospective study on the vasodilatory effect of prostaglandin E1 on blood flow to the gastric tube after esophagectomy is reported.

Methods. Twelve patients with thoracic esophageal cancer who underwent esophagectomy were enrolled in this study. In all patients, the esophagogastrostomy was performed in the cervical region, and the stomach was used for reconstruction. Immediately after the creation of the gastric tube, baseline blood flow was measured at the oral end, in the center, and at the pyloric ring of the gastric tube using a laser Doppler flowmeter. The prostaglandin E1 group (n = 6) was then infused with prostaglandin E1 until postoperative day 2; the control group (n = 6) received saline. At +5 minutes and +40 minutes after administration, blood flow was again measured at the same three sites.

Results. The control group did not show a significant increase of blood flow to any site over time. For the prostaglandin E1 group, blood flow at +40 minutes increased from the baseline measurements significantly at a rate of 63%, 39%, and 36%, respectively.

Conclusions. Prostaglandin E1 has a characteristic vasodilating effect on the area of impaired microcirculation of the gastric tube, thereby increasing blood flow to the affected area.Key Words: PGE1, esophageal reconstruction, blood flow, gastric tube, Laser Doppler flowmeter




This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
M. P. Buise, C. Ince, H. W. Tilanus, J. Klein, D. Gommers, and J. van Bommel
The Effect of Nitroglycerin on Microvascular Perfusion and Oxygenation During Gastric Tube Reconstruction
Anesth. Analg., April 1, 2005; 100(4): 1107 - 1111.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1999 by The Society of Thoracic Surgeons.