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Ann Thorac Surg 1999;67:554-555
© 1999 The Society of Thoracic Surgeons

Case Reports

Treatment of infected left ventricular assist device using antibiotic-impregnated beads

Stephen H. McKellara, Bryce D. Allred, MDb, John D. Marks, BSa, Cris G. Cowley, MDc, David C. Classen, MDd, Scott C. Gardner, MMSca, James W. Long, MDa

a Department of Cardiothoracic, LDS Hospital, Salt Lake City, Utah, USA
b Department of Orthopedic Surgery, LDH Hospital, Salt Lake City, Utah, USA
c Department of Anesthesia, LDS Hospital, Salt Lake City, Utah, USA
d Department of Medicine, LDS Hospital, Salt Lake City, Utah, USA

Accepted for publication July 31, 1998.

Address reprint requests to Dr Long, Mechanical Circulatory Support, LDS Hospital, 324 Tenth Avenue, Suite 160, Salt Lake City, UT 84103
e-mail: jimlong{at}ihc.com

There is no well-established therapy for treating infections of heart-assist or artificial heart devices, a serious problem with life-threatening consequences. We used a promising new approach in which antibiotic-impregnated polymethylmethacrylate beads were placed around an implanted left ventricular assist device to control an external blood pump infection in a bridge-to-transplant patient. In this case report, we describe the potential of antimicrobial-impregnated polymethylmethacrylate beads for in situ control of infections involving external surfaces of cardiovascular devices.




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