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Ann Thorac Surg 1998;66:1411-1413
© 1998 The Society of Thoracic Surgeons

Case Reports

Extramedullary hematopoiesis mimicking metastatic lung carcinoma

F. Ida Hsu, BAa, Daniel A. Filippa, MDb, Hugo Castro-Malaspina, MDc, Robert J. Downey, MDa

a Division of Thoracic Surgery, Memorial-Sloan Kettering Cancer Center, New York, New York, USA
b Department of Pathology, Memorial-Sloan Kettering Cancer Center, New York, New York, USA
c Department of Medicine, Memorial-Sloan Kettering Cancer Center, New York, New York, USA

Accepted for publication April 24, 1998.

Address reprint requests to Dr Downey, Division of Thoracic Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021

Extramedullary hematopoiesis is a rare condition defined as the appearance of hematopoietic elements outside of the bone marrow, which occurs primarily in patients with chronic myeloproliferative disorders or congenital hemolytic anemias. We report a patient who presented with a left lower lobe lung carcinoma and right paravertebral and left pleural masses, initially thought most consistent radiographically with inoperable metastatic disease, until biopsies of the paravertebral and pleural masses established the presence of extramedullary hematopoiesis. The left lower lobe neoplasm was subsequently resected uneventfully.






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