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Ann Thorac Surg 1998;66:1282-1287
© 1998 The Society of Thoracic Surgeons
a Cardiovascular and Thoracic Surgery,University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium
b Cardiology,University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium
c Biostatistics, University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium
Accepted for publication May 4, 1998.
Address reprint requests to Dr Louagie, Cardiovascular and Thoracic Surgery, University Hospital of Mont-Godinne, 1 av Therasse, B5530 Yvoir, Belgium
Background. This study was designed to assess the value of hemodynamic measurements taken intraoperatively in predicting midterm patency of coronary bypass grafts.
Methods. A pulsed Doppler flowmeter was routinely used during operation to determine the hemodynamic parameters of coronary bypass grafts. During a 7-year period, 85 patients underwent angiographic evaluation. As a result, a thorough hemodynamic assessment of 214 grafts (89 arterial and 125 venous) at initial operation was available for analysis.
Results. The overall patency rate was 88.3%. The mean flow measured intraoperatively in 168 intact grafts was 60 ± 3 mL/min (range, 9 to 230 mL/min), and the resistance was 1.8 ± 0.1 peripheral resistance units (range, 0.3 to 9.0 peripheral resistance units). The mean flow was 36 ± 5 mL/min (range, 2 to 107 mL/min), and the resistance was 5.9 ± 2.0 peripheral resistance units (range, 0.6 to 46.0 peripheral resistance units) in 25 grafts found occluded at angiographic evaluation. Multivariate analysis identified three independent variables associated with a reduced patency rate: increased resistance as measured in the graft (p = 0.012), increasing interval of control angiography (p = 0.006), and preoperative cardiogenic shock (p = 0.040).
Conclusions. The prognosis for midterm patency of aortocoronary bypass grafts depends on the intraoperative hemodynamic status.
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