| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 1998;65:1651-1655
© 1998 The Society of Thoracic Surgeons
a Department of Anesthesia, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
b Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
c the Program in Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
d Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
e Department of Cardiothoracic Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
f Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Accepted for publication January 29, 1998.
Address reprint requests to Dr Moody, Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1088
e-mail: (moodyd{at}radmin.rad.bgsm.edu)
Background. Brain injury remains a significant problem in patients undergoing cardiac surgery assisted by cardiopulmonary bypass (CPB). Autopsy brain specimens of patients after cardiac operations with CPB reveal numerous acellular lipid deposits (10 to 70 µm) in the microvasculature. We hypothesize that these small capillary and arterial dilatations result from a diffuse inflammatory response to CPB or from emboli delivered by the bypass circuit. This study was undertaken to determine which aspect of CPB is most clearly associated with these dilatations.
Methods. Thirteen dogs were studied in four groups: group I (n = 3), right-heart CPB; group II (n = 2), lower-extremity CPB; group III (n = 3), hypothermic CPB; and group IV (n = 5), hypothermic CPB with cardiotomy suction. All dogs in all groups were maintained on CPB for 60 minutes and then euthanized. Brain specimens were harvested, fixed in ethanol, embedded in celloidin, and stained with the alkaline phosphate histochemical technique so that dilatations could be counted.
Results. All dogs completed the protocol. The mean density of dilatations per square centimeter for each group was as follows: group I, 1.77 ± 0.77; group II, 4.17 ± 1.65; group III, 4.54 ± 1.69; and group IV, 46.5 ± 14.5. In group IV (cardiotomy suction), dilatation density was significantly higher than in group III (hypothermic cardiopulmonary bypass) (p = 0.04) and all other groups (p = 0.04).
Conclusions. Blood aspirated from the surgical field and subsequently reinfused into dogs undergoing CPB produces a greater density of small capillary and arterial dilatations than CPB without cardiotomy suction, presumably because of lipid microembolization.
This article has been cited by other articles:
|
|
 |
|
  Y.-H. Liu, D.-X. Wang, L.-H. Li, X.-M. Wu, G.-J. Shan, Y. Su, J. Li, Q.-J. Yu, C.-X. Shi, Y.-N. Huang, et al. The Effects of Cardiopulmonary Bypass on the Number of Cerebral Microemboli and the Incidence of Cognitive Dysfunction After Coronary Artery Bypass Graft Surgery Anesth. Analg., October 1, 2009; 109(4): 1013 - 1022. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Wang, D. Bainbridge, J. Martin, and D. Cheng The Efficacy of an Intraoperative Cell Saver During Cardiac Surgery: A Meta-Analysis of Randomized Trials Anesth. Analg., August 1, 2009; 109(2): 320 - 330. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. A. Baker Suction, Salvage, Sutures, and Potions: Blood Management Post-Aprotinin Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2009; 13(2): 122 - 126. [Abstract] [PDF]
|
|
|
|
 |
|
 H. Jonsson, A. Eyjolfsson, S. Scicluna, P. Paulsson, and P. Johnsson Circulating particles during cardiac surgery Interactive CardioVascular and Thoracic Surgery, May 1, 2009; 8(5): 538 - 542. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. C. Groom, R. D. Quinn, P. Lennon, D. J. Donegan, J. H. Braxton, R. S. Kramer, P. W. Weldner, L. Russo, S. D. Blank, A. A. Christie, et al. Detection and Elimination of Microemboli Related to Cardiopulmonary Bypass Circ Cardiovasc Qual Outcomes, May 1, 2009; 2(3): 191 - 198. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Murphy, E. A. Hessel II, and R. C. Groom Optimal Perfusion During Cardiopulmonary Bypass: An Evidence-Based Approach Anesth. Analg., May 1, 2009; 108(5): 1394 - 1417. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Marcoux, M Rosin, E McNair, G Smith, H. Lim, and T Mycyk A comparison of intra-operative cell-saving strategies upon immediate post-operative outcomes after CPB-assisted cardiac procedures Perfusion, May 1, 2008; 23(3): 157 - 164. [Abstract] [PDF]
|
|
|
|
 |
|
 A. Eyjolfsson, S. Scicluna, P. Johnsson, F. Petersson, and H. Jonsson Characterization of Lipid Particles in Shed Mediastinal Blood Ann. Thorac. Surg., March 1, 2008; 85(3): 978 - 981. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. W. Hammon Extracorporeal Circulation: Perfusion System Card. Surg. Adult, January 1, 2008; 3(2008): 350 - 370. [Full Text]
|
|
|
|
|
|
J. W. Hammon Extracorporeal Circulation: Organ Damage Card. Surg. Adult, January 1, 2008; 3(2008): 389 - 414. [Full Text]
|
|
|
|
 |
|
 G. Djaiani, L. Fedorko, M. A. Borger, R. Green, J. Carroll, M. Marcon, and J. Karski Continuous-Flow Cell Saver Reduces Cognitive Decline in Elderly Patients After Coronary Bypass Surgery Circulation, October 23, 2007; 116(17): 1888 - 1895. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. D. Rubens, M. Boodhwani, T. Mesana, D. Wozny, G. Wells, H. J. Nathan, and on behalf of the Cardiotomy Investigators The Cardiotomy Trial: A Randomized, Double-Blind Study to Assess the Effect of Processing of Shed Blood During Cardiopulmonary Bypass on Transfusion and Neurocognitive Function Circulation, September 11, 2007; 116(11_suppl): I-89 - I-97. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Appelblad and K. G. Engstrom Fat content in pericardial suction blood and the efficacy of spontaneous density separation and surface adsorption in a prototype system for fat reduction J. Thorac. Cardiovasc. Surg., August 1, 2007; 134(2): 366 - 372. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. D. Rubens and H. Nathan Lessons learned on the path to a healthier brain: dispelling the myths and challenging the hypotheses Perfusion, May 1, 2007; 22(3): 153 - 160. [Abstract] [PDF]
|
|
|
|
|
|
The Society of Thoracic Surgeons Blood Conservatio, V. A. Ferraris, S. P. Ferraris, S. P. Saha, E. A. Hessel II, C. K. Haan, B. D. Royston, C. R. Bridges, R. S.D. Higgins, G. Despotis, et al. Perioperative Blood Transfusion and Blood Conservation in Cardiac Surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists Clinical Practice Guideline Ann. Thorac. Surg., May 1, 2007; 83(5_Supplement): S27 - S86. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Selim Perioperative Stroke N. Engl. J. Med., February 15, 2007; 356(7): 706 - 713. [Full Text] [PDF]
|
|
|
|
|
|
P. D Raymond, M. Radel, M. J Ray, A. D Hinton-Bayre, and N. A Marsh Investigation of factors relating to neuropsychological change following cardiac surgery Perfusion, January 1, 2007; 22(1): 27 - 33. [Abstract] [PDF]
|
|
|
|
|
|
K. J Lilly, J. M Balaguer, P. A Pirundini, M. A Smith, G. Connelly, L. J. Campbell, P. C Philie, M. McAdams, W. Riley, R. Dekkers, et al. Early results of a comprehensive operative and perfusion strategy to attenuate the incidence of adverse neurological outcomes in on-pump coronary artery bypass grafting (CABG) patients Perfusion, November 1, 2006; 21(6): 311 - 317. [Abstract] [PDF]
|
|
|
|
|
|
Y. Abu-Omar, S. Cader, L. G. Wolf, D. Pigott, P. M. Matthews, and D. P. Taggart Short-term changes in cerebral activity in on-pump and off-pump cardiac surgery defined by functional magnetic resonance imaging and their relationship to microembolization. J. Thorac. Cardiovasc. Surg., November 1, 2006; 132(5): 1119 - 1125. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. A Rodriguez and D. Belway Comparison of two different extracorporeal circuits on cerebral embolization during cardiopulmonary bypass in children Perfusion, September 1, 2006; 21(5): 247 - 253. [Abstract] [PDF]
|
|
|
|
|
|
K. G. Shann, D. S. Likosky, J. M. Murkin, R. A. Baker, Y. R. Baribeau, G. R. DeFoe, T. A. Dickinson, T. J. Gardner, H. P. Grocott, G. T. O'Connor, et al. An evidence-based review of the practice of cardiopulmonary bypass in adults: A focus on neurologic injury, glycemic control, hemodilution, and the inflammatory response. J. Thorac. Cardiovasc. Surg., August 1, 2006; 132(2): 283 - 290.e3. [Full Text] [PDF]
|
|
|
|
|
|
M. Carrier, A. Denault, J. Lavoie, and L. P. Perrault Randomized controlled trial of pericardial blood processing with a cell-saving device on neurologic markers in elderly patients undergoing coronary artery bypass graft surgery. Ann. Thorac. Surg., July 1, 2006; 82(1): 51 - 55. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M Murkin Pathophysiological Basis of CNS Injury in Cardiac Surgical Patients: Detection and Prevention Perfusion, July 1, 2006; 21(4): 203 - 208. [Abstract] [PDF]
|
|
|
|
|
|
Y. Abu-Omar and C. Ratnatunga Cardiopulmonary Bypass and Renal Injury Perfusion, July 1, 2006; 21(4): 209 - 213. [Abstract] [PDF]
|
|
|
|
|
|
C. W. Hogue Jr, C. A. Palin, and J. E. Arrowsmith Cardiopulmonary bypass management and neurologic outcomes: an evidence-based appraisal of current practices. Anesth. Analg., July 1, 2006; 103(1): 21 - 37. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Bokesch, G. A. Izykenova, J. B. Justice, K. A. Easley, and S. A. Dambinova NMDA Receptor Antibodies Predict Adverse Neurological Outcome After Cardiac Surgery in High-Risk Patients Stroke, June 1, 2006; 37(6): 1432 - 1436. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Bronden, M. Dencker, M. Allers, I. Plaza, and H. Jonsson Differential Distribution of Lipid Microemboli After Cardiac Surgery Ann. Thorac. Surg., February 1, 2006; 81(2): 643 - 648. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. M. McKhann, M. A. Grega, L. M. Borowicz Jr, W. A. Baumgartner, and O. A. Selnes Stroke and Encephalopathy After Cardiac Surgery: An Update Stroke, February 1, 2006; 37(2): 562 - 571. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D Belway, F D Rubens, D Wozny, B Henley, and H J Nathan Are we doing everything we can to conserve blood during bypass? A national survey Perfusion, September 1, 2005; 20(5): 237 - 241. [Abstract] [PDF]
|
|
|
|
|
|
A. Khosravi, C. A Skrabal, B. Westphal, G. Kundt, B. Greim, E. Kunesch, A. Liebold, and G. Steinhoff Evaluation of coated oxygenators in cardiopulmonary bypass systems and their impact on neurocognitive function Perfusion, September 1, 2005; 20(5): 249 - 254. [Abstract] [PDF]
|
|
|
|
|
|
H. P. Grocott, H. M. Homi, and F. Puskas Cognitive Dysfunction After Cardiac Surgery: Revisiting Etiology Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2005; 9(2): 123 - 129. [Abstract] [PDF]
|
|
|
|
|
|
K. Prasongsukarn and M. A. Borger Reducing Cerebral Emboli During Cardiopulmonary Bypass Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2005; 9(2): 153 - 158. [Abstract] [PDF]
|
|
|
|
|
|
E. Sirvinskas, T. Lenkutis, L. Raliene, A. Veikutiene, J. Vaskelyte, and I. Marchertiene Influence of residual blood autotransfused from cardiopulmonary bypass circuit on clinical outcome after cardiac surgery Perfusion, March 1, 2005; 20(2): 71 - 75. [Abstract] [PDF]
|
|
|
|
|
|
H. Jonsson, A. Nilsson, F. Petersson, M. Allers, and T. Laurell Particle separation using ultrasound can be used with human shed mediastinal blood Perfusion, January 1, 2005; 20(1): 39 - 43. [Abstract] [PDF]
|
|
|
|
|
|
S Svenmarker, K G Engstrom, T Karlsson, E Jansson, R Lindholm, and T Aberg Influence of pericardial suction blood retransfusion on memory function and release of protein S100B Perfusion, December 1, 2004; 19(6): 337 - 343. [Abstract] [PDF]
|
|
|
|
|
|
S. Bar-Yosef, M. Anders, G. B. Mackensen, L. K. Ti, J. P. Mathew, B. Phillips-Bute, R. H. Messier, H. P. Grocott, and the Neurological Outcome Research Group and CARE I Aortic Atheroma Burden and Cognitive Dysfunction After Coronary Artery Bypass Graft Surgery Ann. Thorac. Surg., November 1, 2004; 78(5): 1556 - 1562. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Jonsson, C. Holm, A. Nilsson, F. Petersson, P. Johnsson, and T. Laurell Particle Separation Using Ultrasound Can Radically Reduce Embolic Load to Brain After Cardiac Surgery Ann. Thorac. Surg., November 1, 2004; 78(5): 1572 - 1577. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. P. Grocott Invited commentary Ann. Thorac. Surg., July 1, 2004; 78(1): 52 - 53. [Full Text] [PDF]
|
|
|
|
|
|
M. Westerberg, A. Bengtsson, and A. Jeppsson Coronary surgery without cardiotomy suction and autotransfusion reduces the postoperative systemic inflammatory response Ann. Thorac. Surg., July 1, 2004; 78(1): 54 - 59. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Abu-Omar, L. Balacumaraswami, D. W. Pigott, P. M. Matthews, and D. P. Taggart Solid and gaseous cerebral microembolization during off-pump, on-pump, and open cardiac surgery procedures J. Thorac. Cardiovasc. Surg., June 1, 2004; 127(6): 1759 - 1765. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Motallebzadeh, R. Kanagasabay, M. Bland, J. C. Kaski, and M. Jahangiri S100 protein and its relation to cerebral microemboli in on-pump and off-pump coronary artery bypass surgery Eur. J. Cardiothorac. Surg., March 1, 2004; 25(3): 409 - 414. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. de Vries, Y. J. Gu, Y. L. Douglas, W. J. Post, H. Lip, and W. van Oeveren Clinical evaluation of a new fat removal filter during cardiac surgery Eur. J. Cardiothorac. Surg., February 1, 2004; 25(2): 261 - 266. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F D Rubens and T Mesana The inflammatory response to cardiopulmonary bypass: a therapeutic overview Perfusion, January 1, 2004; 19(1_suppl): S5 - S12. [Abstract] [PDF]
|
|
|
|
|
|
R. J. Byrick, J. C. Kay, C. D. Mazer, Z. Wang, and J. B. Mullen Dynamic Characteristics of Cerebral Lipid Microemboli: Videomicroscopy Studies in Rats Anesth. Analg., December 1, 2003; 97(6): 1789 - 1794. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Scarborough, W. White, F. E. Derilus, J. P. Mathew, M. F. Newman, and K. P. Landolfo Combined use of off-pump techniques and a sutureless proximal aortic anastomotic device reduces cerebral microemboli generation during coronary artery bypass grafting J. Thorac. Cardiovasc. Surg., November 1, 2003; 126(5): 1561 - 1567. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Ueno, Y. Iguro, H. Yamamoto, R. Sakata, Y. Kakihana, and K. Nakamura Serial measurement of serum S-100B protein as a marker of cerebral damage after cardiac surgery Ann. Thorac. Surg., June 1, 2003; 75(6): 1892 - 1897. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Jewell, E. F. Akowuah, S. K. Suvarna, P. Braidley, D. Hopkinson, and G. Cooper A prospective randomised comparison of cardiotomy suction and cell saver for recycling shed blood during cardiac surgery Eur. J. Cardiothorac. Surg., April 1, 2003; 23(4): 633 - 636. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Johnsson, M. Backstrom, C. Bergh, H. Jonsson, C. Luhrs, and C. Alling Increased S100B in blood after cardiac surgery is a powerful predictor of late mortality Ann. Thorac. Surg., January 1, 2003; 75(1): 162 - 168. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. A. Hessel II and L. H. Edmunds Jr. Extracorporeal Circulation: Perfusion Systems Card. Surg. Adult, January 1, 2003; 2(2003): 317 - 338. [Full Text]
|
|
|
|
|
|
J. W. Hammon Jr. and L. H. Edmunds Jr. Extracorporeal Circulation: Organ Damage Card. Surg. Adult, January 1, 2003; 2(2003): 361 - 388. [Full Text]
|
|
|
|
|
|
T. W. Willcox and R. van Uden Best Practice for Cardiopulmonary Bypass in the High-Risk Elderly Patient Seminars in Cardiothoracic and Vascular Anesthesia, December 1, 2002; 6(4): 293 - 300. [Abstract] [PDF]
|
|
|
|
|
|
H. I Flom-Halvorsen, E Ovrum, F Brosstad, G Tangen, M A. Ringdal, and R Oystese Effects of two differently heparin-coated extracorporeal circuits on markers for brain and myocardial dysfunction Perfusion, September 1, 2002; 17(5): 339 - 345. [Abstract] [PDF]
|
|
|
|
 |
|
 M. Bendszus, W. Reents, D. Franke, W. Mullges, J. Babin-Ebell, M. Koltzenburg, M. Warmuth-Metz, and L. Solymosi Brain Damage After Coronary Artery Bypass Grafting Arch Neurol, July 1, 2002; 59(7): 1090 - 1095. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. De Somer, Y. Van Belleghem, F. Caes, K. Francois, H. Van Overbeke, J. Arnout, Y. Taeymans, and G. Van Nooten Tissue factor as the main activator of the coagulation system during cardiopulmonary bypass J. Thorac. Cardiovasc. Surg., May 1, 2002; 123(5): 951 - 958. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. S. Aldea, L. O. Soltow, W. L. Chandler, C. M. Triggs, C. R. Vocelka, G. I. Crockett, Y. T. Shin, W. E. Curtis, and E. D. Verrier Limitation of thrombin generation, platelet activation, and inflammation by elimination of cardiotomy suction in patients undergoing coronary artery bypass grafting treated with heparin-bonded circuits J. Thorac. Cardiovasc. Surg., April 1, 2002; 123(4): 742 - 755. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A J de Vries, Y J Gu, and W van Oeveren The rationale for fat filtration during cardiac surgery Perfusion, March 1, 2002; 17(2_suppl): 29 - 33. [Abstract] [PDF]
|
|
|
|
|
|
K. Lindmark and K. G. Engstrom Effects of cardiopulmonary bypass on narrow-pore flow behavior of blood J. Thorac. Cardiovasc. Surg., February 1, 2002; 123(2): 381 - 383. [Full Text] [PDF]
|
|
|
|
|
|
A Pierangeli, V Masieri, F Bruzzi, E De Toni, G Grillone, P Boni, and A Delnevo Haemolysis during cardiopulmonary bypass: how to reduce the free haemoglobin by managing the suctioned blood separately Perfusion, December 1, 2001; 16(6): 519 - 524. [Abstract] [PDF]
|
|
|
|
|
|
J. M. Murkin Adverse Central Nervous System Outcomes After Cardiopulmonary Bypass: A Beneficial Effect of Aprotinin? Seminars in Cardiothoracic and Vascular Anesthesia, November 1, 2001; 5(4): 282 - 285. [Abstract] [PDF]
|
|
|
|
|
|
J. M. Murkin Attenuation of neurologic injury during cardiac surgery Ann. Thorac. Surg., November 1, 2001; 72(5): S1838 - 1844. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Salazar, R. J. Wityk, M. A. Grega, L. M. Borowicz, J. R. Doty, J. A. Petrofski, and W. A. Baumgartner Stroke after cardiac surgery: short- and long-term outcomes Ann. Thorac. Surg., October 1, 2001; 72(4): 1195 - 1201. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S J Morris Leukocyte reduction in cardiovascular surgery Perfusion, September 1, 2001; 16(5): 371 - 380. [PDF]
|
|
|
|
|
|
L.-C. Hsu Heparin-coated cardiopulmonary bypass circuits: current status Perfusion, September 1, 2001; 16(5): 417 - 428. [Abstract] [PDF]
|
|
|
|
|
|
J. E. Arrowsmith and J. J. Dunning Normothermic cardiopulmonary bypass is beneficial for cognitive brain function after coronary artery bypass grafting - a prospective randomized trial Eur. J. Cardiothorac. Surg., May 1, 2001; 19(5): 732 - 733. [Full Text] [PDF]
|
|
|
|
|
|
S. Westaby, K. Saatvedt, S. White, T. Katsumata, W. van Oeveren, and P. W. Halligan Is there a relationship between cognitive dysfunction and systemic inflammatory response after cardiopulmonary bypass? Ann. Thorac. Surg., February 1, 2001; 71(2): 667 - 672. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Booke, H. Van Aken, M. Storm, F. Fritzsche, S. Wirtz, and F. Hinder Fat Elimination from Autologous Blood Anesth. Analg., February 1, 2001; 92(2): 341 - 343. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Neville, J. Butterworth, R. L. James, J. W. Hammon, and D. A. Stump Similar neurobehavioral outcome after valve or coronary artery operations despite differing carotid embolic counts J. Thorac. Cardiovasc. Surg., January 1, 2001; 121(1): 0125 - 136. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. H. Kincaid, T. J. Jones, D. A. Stump, W. R. Brown, D. M. Moody, D. D. Deal, and J. W. Hammon Jr Processing scavenged blood with a cell saver reduces cerebral lipid microembolization Ann. Thorac. Surg., October 1, 2000; 70(4): 1296 - 1300. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. E. Anderson, L.-O. Hansson, J. Liska, G. Settergren, and J. Vaage The effect of cardiotomy suction on the brain injury marker S100{beta} after cardiopulmonary bypass Ann. Thorac. Surg., March 1, 2000; 69(3): 847 - 850. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. R. Brown, D. M. Moody, V. R. Challa, D. A. Stump, and J. W. Hammon Longer Duration of Cardiopulmonary Bypass Is Associated With Greater Numbers of Cerebral Microemboli Stroke, March 1, 2000; 31(3): 707 - 713. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Westaby, K. Saatvedt, S. White, T. Katsumata, W. van Oeveren, N. K. Bhatnagar, S. Brown, and P. W. Halligan IS THERE A RELATIONSHIP BETWEEN SERUM S-100{beta} PROTEIN AND NEUROPSYCHOLOGIC DYSFUNCTION AFTER CARDIOPULMONARY BYPASS? J. Thorac. Cardiovasc. Surg., January 1, 2000; 119(1): 132 - 137. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. Bokesch Breaking down the blood-brain barrier Ann. Thorac. Surg., December 1, 1999; 68(6): 2013 - 2014. [Full Text] [PDF]
|
|
|
|
|
|
G. S. Aldea Heparin-Bonded Circuits Decrease Thromboembolic Complications and Improve Outcomes in Patients Undergoing Coronary Artery Bypass Graft Surgery Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 1999; 3(1): 9 - 16. [Abstract] [PDF]
|
|
|
|
|
|
D. A. Stump, W. R. Brown, D. M. Moody, K. D. Rorie, J. C. Manuel, N. D. Kon, J. B. Butterworth, and J. W. Hammon Microemboli and Neurologic Dysfunction After Cardiovascular Surgery Seminars in Cardiothoracic and Vascular Anesthesia, March 1, 1999; 3(1): 47 - 54. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
