ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Joel D. Cooper
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bril, V.
Right arrow Articles by Cooper, J. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bril, V.
Right arrow Articles by Cooper, J. D.

Ann Thorac Surg 1998;65:1520-1522
© 1998 The Society of Thoracic Surgeons

Original articles: general thoracic

Long-Term Clinical Outcome After Transcervical Thymectomy for Myasthenia Gravis

Vera Bril, MDa, Jasna Kojic, MDa, Werner K. Ilse, MDa, Joel D. Cooper, MDa

a Division of Neurology, The Toronto Hospital, General Division, Toronto, Ontario, Canada

Accepted for publication December 18, 1997.

Address reprint requests to Dr Bril, The Toronto Hospital, General Division, EN11-209, 200 Elizabeth St, Toronto, Ont Canada M5G 2C4
e-mail: (vera.bril{at}utoronto.ca)

Background. We reviewed the long-term clinical outcome after transcervical thymectomy for generalized myasthenia gravis without thymoma in 52 patients who had this procedure at The Toronto Hospital between 1977 and 1986, and compared the results with those reported after more radical surgical approaches.

Methods. Preoperative and postoperative patient evaluations were based on a modified Osserman classification. We defined complete remission as asymptomatic with normal strength and without medications for myasthenia gravis. The complete remission rate was selected as the best measure for comparison between different surgical approaches.

Results. The 52 patients were followed up for a mean of 8.4 years (±6.1 years [standard deviation]). The preoperative mean Osserman grade was 2.7 compared with 0.4 at final follow-up. Complete remission occurred in 44.2% of patients. Similar results are reported after transsternal thymectomy.

Conclusions. Comparable results after transcervical and transsternal thymectomy favor the use of the less radical approach.




This article has been cited by other articles:


Home page
 ICVTSHome page
A. Toker, S. Tanju, S. Ziyade, B. Ozkan, Z. Sungur, Y. Parman, P. Serdaroglu, and F. Deymeer
Early outcomes of video-assisted thoracoscopic resection of thymus in 181 patients with myasthenia gravis: who are the candidates for the next morning discharge?
Interactive CardioVascular and Thoracic Surgery, December 1, 2009; 9(6): 995 - 998.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
C. Prokakis, E. Koletsis, S. Salakou, E. Apostolakis, N. Baltayiannis, A. Chatzimichalis, T. Papapetropoulos, and D. Dougenis
Modified maximal thymectomy for myasthenia gravis: effect of maximal resection on late neurologic outcome and predictors of disease remission.
Ann. Thorac. Surg., November 1, 2009; 88(5): 1638 - 1645.
[Abstract] [Full Text] [PDF]

Home page
 Asian Cardiovasc. Thorac. Ann.Home page
M. Aghajanzadeh, H. Khoshrang, A. Mohammadzadeh, S. A Roudbari, and A. R Ghayeghran
Thymectomy for Myasthenia Gravis: Prognostic Factors in 70 Patients
Asian Cardiovasc Thorac Ann, October 1, 2007; 15(5): 371 - 375.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
H. Kattach, K. Anastasiadis, J. Cleuziou, C. Buckley, B. Shine, R. Pillai, and C. Ratnatunga
Transsternal Thymectomy for Myasthenia Gravis: Surgical Outcome
Ann. Thorac. Surg., January 1, 2006; 81(1): 305 - 308.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
A. Granetzny, A. Hatem, A. Shalaby, and A. Boseila
Manubriotomy versus median sternotomy in thymectomy for myasthenia gravis. Evaluation of the pulmonary status
Eur. J. Cardiothorac. Surg., March 1, 2005; 27(3): 361 - 366.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. Endo, T. Yamaguchi, N. Saito, S. Otani, T. Hasegawa, Y. Sato, and Y. Sohara
Experience with programmed steroid treatment with thymectomy in nonthymomatous myasthenia gravis
Ann. Thorac. Surg., May 1, 2004; 77(5): 1745 - 1750.
[Abstract] [Full Text] [PDF]

Home page
 Asian Cardiovasc. Thorac. Ann.Home page
Y. El-Medany, W. Hajjar, M. Essa, K. Al-Kattan, Z. Hariri, and M. Ashour
Predictors of Outcome for Myasthenia Gravis after Thymectomy
Asian Cardiovasc Thorac Ann, December 1, 2003; 11(4): 323 - 327.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
M. de Perrot, V. Bril, K. McRae, and S. Keshavjee
Impact of minimally invasive trans-cervical thymectomy on outcome in patients with myasthenia gravis
Eur. J. Cardiothorac. Surg., November 1, 2003; 24(5): 677 - 683.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. de Perrot, J. Liu, V. Bril, K. McRae, A. Bezjak, and S. H. Keshavjee
Prognostic significance of thymomas in patients with myasthenia gravis
Ann. Thorac. Surg., November 1, 2002; 74(5): 1658 - 1662.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. B. Shrager, M. E. Deeb, R. Mick, C. J. Brinster, H. E. Childers, M. B. Marshall, J. C. Kucharczuk, S. L. Galetta, S. J. Bird, and L. R. Kaiser
Transcervical thymectomy for myasthenia gravis achieves results comparable to thymectomy by sternotomy
Ann. Thorac. Surg., August 1, 2002; 74(2): 320 - 327.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
T. Roth, R. Ackermann, R. Stein, R. Inderbitzi, K. Rosler, and R.A. Schmid
Thirteen years follow-up after radical transsternal thymectomy for myasthenia gravis. Do short-term results predict long-term outcome?
Eur. J. Cardiothorac. Surg., April 1, 2002; 21(4): 664 - 670.
[Abstract] [Full Text] [PDF]

Home page
 J Child NeurolHome page
H. K. Kolski, P. C.W. Kim, and J. Vajsar
Video-Assisted Thoracoscopic Thymectomy in Juvenile Myasthenia Gravis
J Child Neurol, August 1, 2001; 16(8): 569 - 573.
[Abstract] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. M. Budde, C. D. Morris, A. A. Gal, K. A. Mansour, and J. I. Miller Jr
Predictors of outcome in thymectomy for myasthenia gravis
Ann. Thorac. Surg., July 1, 2001; 72(1): 197 - 202.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
A. Mussi, M. Lucchi, L. Murri, R. Ricciardi, L. Luchini, and C. A. Angeletti
Extended thymectomy in myasthenia gravis: a team-work of neurologist, thoracic surgeon and anaesthesist may improve the outcome
Eur. J. Cardiothorac. Surg., May 1, 2001; 19(5): 570 - 575.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
E. Pompeo, I. Nofroni, N. Iavicoli, and T. C. Mineo
Thoracoscopic completion thymectomy in refractory nonthymomatous myasthenia
Ann. Thorac. Surg., September 1, 2000; 70(3): 918 - 923.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
A. Jaretzki III, R. J. Barohn, R. M. Ernstoff, H. J. Kaminski, J. C. Keesey, A. S. Penn, and D. B. Sanders
Myasthenia gravis: Recommendations for clinical research standards
Neurology, July 12, 2000; 55(1): 16 - 23.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. Jaretzki III, R. J. Barohn, R. M. Ernstoff, H. J. Kaminski, J. C. Keesey, A. S. Penn, and D. B. Sanders
Myasthenia gravis: recommendations for clinical research standards
Ann. Thorac. Surg., July 1, 2000; 70(1): 327 - 334.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. C. Mineo, E. Pompeo, T. E. Lerut, G. Bernardi, W. Coosemans, and I. Nofroni
Thoracoscopic thymectomy in autoimmune myasthenia: results of left-sided approach
Ann. Thorac. Surg., May 1, 2000; 69(5): 1537 - 1541.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
F. Venuta, E. A. Rendina, T. De Giacomo, G. Della Rocca, G. Antonini, A. M. Ciccone, C. Ricci, and G. F. Coloni
Thymectomy for myasthenia gravis: a 27-year experience
Eur. J. Cardiothorac. Surg., May 1, 1999; 15(5): 621 - 625.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. Jaretzki III
Outcome after transcervical thymectomy.
Ann. Thorac. Surg., February 1, 1999; 67(2): 592 - 593.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1998 by The Society of Thoracic Surgeons.