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Ann Thorac Surg 1997;64:1822-1824
© 1997 The Society of Thoracic Surgeons

Case Report

Posttransplantation Lymphoproliferative Disorder in Cardiac Transplant Allografts

Alan J. Ying, BA, P. David Myerowitz, MD, William L. Marsh, Jr, MD

Department of Pathology and Division of Thoracic and Cardiovascular Surgery, The Ohio State University Medical Center, Columbus, Ohio

Accepted for publication July 18, 1997.

Posttransplantation lymphoproliferative disorder occurs in 1.5% to 13% of heart transplant recipients and rarely involves the allograft. We report a case of posttransplantation lymphoproliferative disorder restricted to the mitral valve in a heart transplant recipient. Thirteen cases of cardiac allograft involvement by posttransplantation lymphoproliferative disorder are reported in the literature. None are restricted to the allograft. Five specify sites of cardiac involvement. Valvular masses without infection necessitate evaluation for posttransplantation lymphoproliferative disorder involvement of the cardiac allograft valve.




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