ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jackson, M. R.
Right arrow Articles by Alving, B. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jackson, M. R.
Right arrow Articles by Alving, B. M.

Ann Thorac Surg 1997;64:1815-1817
© 1997 The Society of Thoracic Surgeons

Case Report

Heparinoid Anticoagulation and Topical Fibrin Sealant in Heparin-Induced Thrombocytopenia

Mark R. Jackson, MD, Christopher A. Danby, MD, Barbara M. Alving, MD

Department of Surgery, Walter Reed Army Medical Center, Washington, DC

Accepted for publication July 11, 1997.

The development of heparin-induced thrombocytopenia in patients who require systemic anticoagulation for cardiac and vascular operations poses a therapeutic dilemma because no alternative anticoagulants are generally available. Heparinoid (Org 10172) has been used as an alternative anticoagulant under protocol or on a compassionate use basis, and has recently been approved by the Food and Drug Administration. There is, however, no heparinoid antagonist to reverse the anticoagulation. This report describes the combined use of heparinoid anticoagulation and adjunctive fibrin sealant for topical hemostasis in a patient with heparin-induced thrombocytopenia. Recommendations for perioperative monitoring of heparinoid anticoagulation are provided.




This article has been cited by other articles:


Home page
 BloodHome page
B. M. Alving
How I treat heparin-induced thrombocytopenia and thrombosis
Blood, January 1, 2003; 101(1): 31 - 37.
[Full Text] [PDF]

Home page
 Anesth. Analg.Home page
Y. Sun, P. E. Greilich, S. I. O. Wilson, M. R. Jackson, and C. W. Whitten
The Use of Lepirudin for Anticoagulation in Patients with Heparin-Induced Thrombocytopenia During Major Vascular Surgery
Anesth. Analg., February 1, 2001; 92(2): 344 - 346.
[Abstract] [Full Text] [PDF]

Home page
 ASH Education BookHome page
K. R. McCrae, J. B. Bussel, P. M. Mannucci, G. Remuzzi, and D. B. Cines
Platelets: An Update on Diagnosis and Management of Thrombocytopenic Disorders
Hematology, January 1, 2001; 2001(1): 282 - 305.
[Abstract] [Full Text] [PDF]

Home page
 PERSPECT VASC SURG ENDOVASC THERHome page
M. R. Jackson
Fibrin Sealant as a Hemostatic Agent in Vascular Surgery
Perspectives in Vascular Surgery and Endovascular Therapy, January 1, 2000; 13(1): 85 - 94.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1997 by The Society of Thoracic Surgeons.