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Ann Thorac Surg 1997;64:1456-1458
© 1997 The Society of Thoracic Surgeons

Case Report

Single-Lung Transplantation in a Patient With Cystic Fibrosis and an Asymmetric Thorax

Jarowit A. Piotrowski, MD, Fred H. Splittgerber, MD, Terence J. Donovan, MD, Felix Ratjen, MD, Hans-R. Zerkowski, MD

Departments of Thoracic and Cardiovascular Surgery and Paediatrics, Essen University Medical School, Essen, Germany

Accepted for publication July 1, 1997.

We report metachronous single-lung transplantation for cystic fibrosis after contralateral pneumonectomy. Kyphoscoliosis and mediastinal shift required careful donor-lung sizing with computed tomography and was not dependent on typical parameters. Severe reperfusion injury was treated with nitric oxide, C1-esterase inhibitor, and continuous venovenous hemodialysis. The patient was extubated on the fifth postoperative day and is alive and well. We conclude that single-lung transplantation after contralateral pneumonectomy for patients with cystic fibrosis and an asymmetric chest and evident lung volume mismatch may be an acceptable functional therapeutic option.


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Invited Commentary
Richard J. Novick
Ann. Thorac. Surg. 1997 64: 1456-1459. [Extract] [Full Text]



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