HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Yasuharu Imai Yoshinori Takanashi Shuichi Hoshino Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nagashima, M. Articles by Aoki, M. Search for Related Content PubMed PubMed Citation Articles by Nagashima, M. Articles by Aoki, M.

Ann Thorac Surg 1997;64:730-734
© 1997 The Society of Thoracic Surgeons

---

Original Article: Cardiovascular

Ventricular Hypertrophy as a Risk Factor in Ventricular Septation for Double-Inlet Left Ventricle

Department of Pediatric Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College, Tokyo, Japan

Accepted for publication March 5, 1997.

Background. Ventricular septation is an option for surgical correction of double-inlet or common-inlet left ventricle. However, the surgical risk factors of ventricular septation remain unknown.

Methods. Twenty-three patients with double-inlet or common-inlet left ventricle underwent ventricular septation. Preoperative data were compared between the survivors (n = 18) and the nonsurvivors (n = 5) to assess surgical risk factors.

Results. There were two early deaths (9.5%) and three late deaths (14.3%). Nonsurvivors of ventricular septation were significantly older at the time of operation (14.0 ± 6.0 versus 7.0 ± 5.4 years; p < 0.05) and had greater left ventricular mass (383% ± 100% versus 206% ± 57% of normal predicted value; p < 0.005) and greater left ventricular mass to left ventricular end-diastolic volume ratio (1.84% ± 1.18% versus 0.77% ± 0.17%/% of normal predicted value; p < 0.005). Univariate logistic regression analysis also revealed age at operation (p < 0.05) and mass/end-diastolic volume ratio (p < 0.05) as significant risk factors for death after operation. Multivariate regression analysis revealed that age at operation positively influenced increased mass/end-diastolic volume ratio (p < 0.001). These findings indicated that ventricular hypertrophy was one of the risk factors for ventricular septation, which had a tendency to progress with age.

Conclusions. Early operation before progression of ventricular hypertrophy is recommended in patients with double-inlet or common-inlet left ventricle who have suitable anatomy for the ventricular septation procedure.

This article has been cited by other articles:

				R. E. Margossian, D. Solowiejczyk, F. Bourlon, H. Apfel, W. M. Gersony, A. J. Hordof, and J. Quaegebeur Septation of the single ventricle: Revisited J. Thorac. Cardiovasc. Surg., September 1, 2002; 124(3): 442 - 447. [Abstract] [Full Text] [PDF]

				A. Hager, H. Kaemmerer, A. Eicken, S. Fratz, and J. Hess Long-term survival of patients with univentricular heart not treated surgically J. Thorac. Cardiovasc. Surg., June 1, 2002; 123(6): 1214 - 1217. [Full Text] [PDF]

				R. H. Anderson and S. Y. Ho Which hearts are unsuitable for biventricular correction? Ann. Thorac. Surg., August 1, 1998; 66(2): 621 - 626. [Abstract] [Full Text] [PDF]