ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Derek D. Muehrcke
Delos M. Cosgrove, III
Bruce W. Lytle
Paul C. Taylor
Floyd D. Loop
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Muehrcke, D. D.
Right arrow Articles by Loop, F. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Muehrcke, D. D.
Right arrow Articles by Loop, F. D.

Ann Thorac Surg 1997;63:1718-1724
© 1997 The Society of Thoracic Surgeons

Original Article: Cardiovascular

Is There an Advantage to Repairing Infected Mitral Valves?

Derek D. Muehrcke, MD, Delos M. Cosgrove, III, MD, Bruce W. Lytle, MD, Paul C. Taylor, MD, Alexandra M. Burgar, BS, Celeste P. Durnwald, BS, Floyd D. Loop, MD

Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio

Accepted for publication December 24, 1996.

Background. The therapy for native mitral valve endocarditis is in evolution. Antibiotics have significantly improved survival rates, but patients with complications of endocarditis may require surgical treatment.

Methods. Between January 1985 and December 1995, 146 patients underwent surgical therapy (repair or replacement) for native mitral valve endocarditis. All patients had documented bacterial endocarditis. Univariate and multivariate analyses were performed to determine predictors of hospital death, long-term event-free survival, and probability of repair. Patients were evaluated in three groups: all patients, patients with acute endocarditis, and patients with chronic endocarditis.

Results. There were ten hospital deaths (6.8%). Patients undergoing repair had a lower hospital mortality rate (p = 0.008) then those having replacement. Event-free survival was improved after mitral valve repair in the overall group (p = 0.02) and in the group with healed (chronic) endocarditis (p = 0.05). Although the acute endocarditis group demonstrated an improved event-free survival rate after mitral valve repair versus replacement (74% versus 20% at 6 years), this did not reach statistical significance.

Conclusions. We conclude that mitral valve repair is preferable to mitral valve replacement when possible, in patients with complications of endocarditis, as repair results in a lower hospital mortality and an improved long-term survival.




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
M. A. Smith and D. D. Yuh
Bioprosthetic mitral valve implantation for active mitral valve endocarditis in third degree thorax burn.
Ann. Thorac. Surg., May 1, 2008; 85(5): 1791 - 1792.
[Abstract] [Full Text] [PDF]

Home page
 Card Surg AdultHome page
S. C. Stamou, G. Petterson, and A. M. Gillinov
Surgical Treatment of Mitral Valve Endocarditis
Card. Surg. Adult, January 1, 2008; 3(2008): 1069 - 1078.
[Full Text]

Home page
 Ann. Thorac. Surg.Home page
E. M. Delmo Walter, M. Musci, N. Nagdyman, M. Hubler, F. Berger, and R. Hetzer
Mitral Valve Repair for Infective Endocarditis in Children
Ann. Thorac. Surg., December 1, 2007; 84(6): 2059 - 2065.
[Abstract] [Full Text] [PDF]

Home page
 Asian Cardiovasc. Thorac. Ann.Home page
H. Morimoto, K. Tsuchiya, M. Nakajima, O. Akashi, and K. Kato
Mitral Valve Repair for Extended Commissural Prolapse Involving Complex Prolapse
Asian Cardiovasc Thorac Ann, June 1, 2007; 15(3): 210 - 213.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
L. de Kerchove, J.-L. Vanoverschelde, A. Poncelet, D. Glineur, J. Rubay, F. Zech, P. Noirhomme, and G. El Khoury
Reconstructive surgery in active mitral valve endocarditis: feasibility, safety and durability
Eur. J. Cardiothorac. Surg., April 1, 2007; 31(4): 592 - 599.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
H. H.H. Feringa, L. J. Shaw, D. Poldermans, S. Hoeks, E. E. van der Wall, R. A.E. Dion, and J. J. Bax
Mitral Valve Repair and Replacement in Endocarditis: A Systematic Review of Literature
Ann. Thorac. Surg., February 1, 2007; 83(2): 564 - 570.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
S M Tuladhar and P P Punjabi
Surgical reconstruction of the mitral valve
Heart, October 1, 2006; 92(10): 1373 - 1377.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
H. H.H. Feringa, J. J. Bax, P. Klein, R. J.M. Klautz, J. Braun, Ernst. E. van der Wall, D. Poldermans, and R. A.E. Dion
Outcome after mitral valve repair for acute and healed infective endocarditis
Eur. J. Cardiothorac. Surg., March 1, 2006; 29(3): 367 - 373.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
G Doukas, M Oc, C Alexiou, A W Sosnowski, N J Samani, and T J Spyt
Mitral valve repair for active culture positive infective endocarditis
Heart, March 1, 2006; 92(3): 361 - 363.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
S A Livesey
Mitral valve reconstruction in the presence of infection
Heart, March 1, 2006; 92(3): 289 - 290.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. S. Gammie, S. M. O'Brien, B. P. Griffith, and E. D. Peterson
Surgical Treatment of Mitral Valve Endocarditis in North America
Ann. Thorac. Surg., December 1, 2005; 80(6): 2199 - 2204.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
E. Ruttmann, C. Legit, G. Poelzl, S. Mueller, O. Chevtchik, M. Cottogni, H. Ulmer, O. Pachinger, G. Laufer, and L. C. Mueller
Mitral valve repair provides improved outcome over replacement in active infective endocarditis
J. Thorac. Cardiovasc. Surg., September 1, 2005; 130(3): 765 - 771.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
R. Zegdi, M. Debieche, C. Latremouille, D. Lebied, C. Chardigny, J.-M. Grinda, S. Chauvaud, A. Deloche, A. Carpentier, and J.-N. Fabiani
Long-Term Results of Mitral Valve Repair in Active Endocarditis
Circulation, May 17, 2005; 111(19): 2532 - 2536.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
P Tornos, B Iung, G Permanyer-Miralda, G Baron, F Delahaye, C. Gohlke-Barwolf, E G Butchart, P Ravaud, and A Vahanian
Infective endocarditis in Europe: lessons from the Euro heart survey
Heart, May 1, 2005; 91(5): 571 - 575.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
B. Iung, J. Rousseau-Paziaud, B. Cormier, E. Garbarz, O. Fondard, E. Brochet, C. Acar, J.-P. Couetil, U. Hvass, and A. Vahanian
Contemporary results of mitral valve repair for infective endocarditis
J. Am. Coll. Cardiol., February 4, 2004; 43(3): 386 - 392.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
O. Bech-Hanssen, T. Ryden, H. Schersten, A. Oden, F. Nilsson, and A. Jeppsson
Mortality after mitral regurgitation surgery: importance of clinical and echocardiographic variables
Eur. J. Cardiothorac. Surg., November 1, 2003; 24(5): 723 - 730.
[Abstract] [Full Text] [PDF]

Home page
 Card Surg AdultHome page
A. M. Gillinov and D. M. Cosgrove III
Mitral Valve Repair
Card. Surg. Adult, January 1, 2003; 2(2003): 933 - 950.
[Full Text]

Home page
 Card Surg AdultHome page
F. Filsoufi and D. H. Adams
Surgical Treatment of Mitral Valve Endocarditis
Card. Surg. Adult, January 1, 2003; 2(2003): 987 - 997.
[Full Text]

Home page
 Ann. Thorac. Surg.Home page
A. M. Gillinov, C. N. Faber, J. F. Sabik, G. Pettersson, B. P. Griffin, S. M. Gordon, E. Hayek, L. M. Di Paola, D. M. Cosgrove III, and E. H. Blackstone
Endocarditis after mitral valve repair
Ann. Thorac. Surg., June 1, 2002; 73(6): 1813 - 1816.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
J M Guerra, M P Tornos, G Permanyer-Miralda, B Almirante, M Murtra, and J Soler-Soler
Long term results of mechanical prostheses for treatment of active infective endocarditis
Heart, July 1, 2001; 86(1): 63 - 68.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. M. Gillinov, R. Diaz, E. H. Blackstone, G. B. Pettersson, J. F. Sabik, B. W. Lytle, and D. M. Cosgrove III
Double valve endocarditis
Ann. Thorac. Surg., June 1, 2001; 71(6): 1874 - 1879.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
C. Alexiou, S. M. Langley, H. Stafford, J. A. Lowes, S. A. Livesey, and J. L. Monro
Surgery for active culture-positive endocarditis: determinants of early and late outcome
Ann. Thorac. Surg., May 1, 2000; 69(5): 1448 - 1454.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
J.-J. Monsuez, D. Vittecoq, C. Acar, J. Evans, S. Witchitz, and N. Kouchoukos
RECURRENT INFECTIVE ENDOCARDITIS ONE YEAR AFTER MITRAL REPAIR IN A WOMAN ADDICTED TO DRUGS
J. Thorac. Cardiovasc. Surg., November 1, 1997; 114(5): 864 - 866.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1997 by The Society of Thoracic Surgeons.