ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Michael Argenziano
Lyall A. Gorenstein
Eric A. Rose
Kenneth M. Steinglass
Mark E. Ginsburg
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Argenziano, M.
Right arrow Articles by Ginsburg, M. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Argenziano, M.
Right arrow Articles by Ginsburg, M. E.

Ann Thorac Surg 1996;62:1588-1597
© 1996 The Society of Thoracic Surgeons

Original Articles: General Thoracic

Extended Indications for Lung Volume Reduction Surgery in Advanced Emphysema

Michael Argenziano, MD, Nader Moazami, MD, Byron Thomashow, MD, Patricia A. Jellen, MSN, Lyall A. Gorenstein, MD, Eric A. Rose, MD, Alan D. Weinberg, MS, Kenneth M. Steinglass, MD, Mark E. Ginsburg, MD

Divisions of Cardiothoracic Surgery and Pulmonary Medicine, Columbia University College of Physicians and Surgeons, New York, New York

Background. Lung volume reduction surgery has shown early promise as a palliative therapy in severe emphysema. Selection of potential candidates has been based on certain functional and anatomic criteria, and a variety of operative contraindications have been proposed.

Methods. Over 15 months, we performed lung volume reduction surgery in 85 patients selected on the basis of severe hyperinflation with air trapping, diaphragmatic dysfunction, and disease heterogeneity. Patients were not excluded on the basis of severe hypercapnia, steroid dependence, profound pulmonary dysfunction, or inability to complete preoperative rehabilitation.

Results. We observed significant improvements in pulmonary function, exercise capacity, and dyspnea, with an acceptable 30-day perioperative mortality of 7% and actuarial survival of 90% and 83% at 6 and 12 months, respectively. In each "high-risk" group, perioperative mortality, actuarial survival to 1 year, and functional results were equivalent, and in some cases superior, to those in the corresponding "low-risk" patients.

Conclusions. Severe hypercapnia, steroid dependence, profound pulmonary dysfunction, and inability to complete preoperative rehabilitation do not preclude successful lung volume reduction surgery and should not be regarded as absolute exclusionary criteria.




This article has been cited by other articles:


Home page
 Proc Am Thorac SocHome page
G. J. Criner, A. L. Sternberg, and for the National Emphysema Treatment Trial Researc
A Clinician's Guide to the Use of Lung Volume Reduction Surgery
Proceedings of the ATS, May 1, 2008; 5(4): 461 - 467.
[Abstract] [Full Text] [PDF]

Home page
 Clin TrialsHome page
S. M Lee, R. Wise, A. L Sternberg, J. Tonascia, S. Piantadosi, and National Emphysema Treatment Trial Research Group
Methodologic issues in terminating enrollment of a subgroup of patients in a multicenter randomized trial
Clinical Trials, June 1, 2004; 1(3): 326 - 338.
[Abstract] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
Safety and efficacy of median sternotomy versus video-assisted thoracic surgery for lung volume reduction surgery
J. Thorac. Cardiovasc. Surg., May 1, 2004; 127(5): 1350 - 1360.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
B. F. Meyers, R. D. Yusen, T. J. Guthrie, G. A. Patterson, S. S. Lefrak, G. E. Davis, and J. D. Cooper
Results of lung volume reduction surgery in patients meeting a National Emphysema Treatment Trial high-risk criterion
J. Thorac. Cardiovasc. Surg., March 1, 2004; 127(3): 829 - 835.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Decramer
Treatment of chronic respiratory failure: lung volume reduction surgery versus rehabilitation
Eur. Respir. J., November 16, 2003; 22(47_suppl): 47s - 56s.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
B F Meyers and G A Patterson
Chronic obstructive pulmonary disease * 10: Bullectomy, lung volume reduction surgery, and transplantation for patients with chronic obstructive pulmonary disease
Thorax, July 1, 2003; 58(7): 634 - 638.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
R S Goldstein, T R J Todd, G Guyatt, S Keshavjee, T E Dolmage, S van Rooy, B Krip, F Maltais, P LeBlanc, S Pakhale, et al.
Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease
Thorax, May 1, 2003; 58(5): 405 - 410.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
Patients at High Risk of Death after Lung-Volume-Reduction Surgery
N. Engl. J. Med., October 11, 2001; 345(15): 1075 - 1083.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
W. CHATILA, S. FURUKAWA, and G. J. CRINER
Acute Respiratory Failure after Lung Volume Reduction Surgery
Am. J. Respir. Crit. Care Med., October 1, 2000; 162(4): 1292 - 1296.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
W. Wisser, O. Senbaklavaci, C. Ozpeker, M. Ploner, T. Wanke, E. Tschernko, E. Wolner, and W. Klepetko
Is long-term functional outcome after lung volume reduction surgery predictable?
Eur. J. Cardiothorac. Surg., June 1, 2000; 17(6): 666 - 672.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
K. S. Naunheim, S. R. Hazelrigg, L. R. Kaiser, R. J. Keenan, J. E. Bavaria, R. J. Landreneau, J. Osterloh, and C. A. Keller
Risk analysis for thoracoscopic lung volume reduction: a multi-institutional experience
Eur. J. Cardiothorac. Surg., June 1, 2000; 17(6): 673 - 679.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. L. Serna, M. Brenner, K. E. Osann, R. J. McKenna Jr, J. C. Chen, R. J. Fischel, B. U. Jones, A. F. Gelb, and A. F. Wilson
SURVIVAL AFTER UNILATERAL VERSUS BILATERAL LUNG VOLUME REDUCTION SURGERY FOR EMPHYSEMA
J. Thorac. Cardiovasc. Surg., December 1, 1999; 118(6): 1101 - 1109.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
T. N. E. T. T. R. Group
Rationale and Design of the National Emphysema Treatment Trial : A Prospective Randomized Trial of Lung Volume Reduction Surgery
Chest, December 1, 1999; 116(6): 1750 - 1761.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
RATIONALE AND DESIGN OF THE NATIONAL EMPHYSEMA TREATMENT TRIAL (NETT): A PROSPECTIVE RANDOMIZED TRIAL OF LUNG VOLUME REDUCTION SURGERY
J. Thorac. Cardiovasc. Surg., September 1, 1999; 118(3): 518 - 528.
[Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
W. Wisser, W. Klepetko, O. Senbaklavaci, T. Wanke, E. Gruber, E. Tschernko, and E. Wolner
Chronic hypercapnia should not exclude patients from lung volume reduction surgery
Eur. J. Cardiothorac. Surg., August 1, 1999; 14(2): 107 - 112.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
H. E. FESSLER and R. A. WISE
Lung Volume Reduction Surgery . Is Less Really More?
Am. J. Respir. Crit. Care Med., April 1, 1999; 159(4): 1031 - 1035.
[Full Text] [PDF]

Home page
 ChestHome page
M. Brenner, R. J. McKenna Jr., J. C. Chen, K. Osann, L. Powell, A. F. Gelb, R. J. Fischel, and A. F. Wilson
Survival Following Bilateral Staple Lung Volume Reduction Surgery for Emphysema
Chest, February 1, 1999; 115(2): 390 - 396.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
G. M. O'Brien, S. Furukawa, A. M. Kuzma, F. Cordova, and G. J. Criner
Improvements in Lung Function, Exercise, and Quality of Life in Hypercapnic COPD Patients After Lung Volume Reduction Surgery
Chest, January 1, 1999; 115(1): 75 - 84.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
H. Date, K. Goto, R. Souda, H. Nagashima, I. Togami, S. Endou, M. Aoe, M. Yamashita, A. Andou, and N. Shimizu
Bilateral Lung Volume Reduction Surgery via Median Sternotomy for Severe Pulmonary Emphysema
Ann. Thorac. Surg., April 1, 1998; 65(4): 939 - 942.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. J. DeRose Jr, M. Argenziano, N. El Amir, L. A. Gorenstein, K. M. Steinglass, B. Thomashow, and M. E. Ginsburg
Lung Reduction Operation and Resection of Pulmonary Nodules in Patients With Severe Emphysema
Ann. Thorac. Surg., February 1, 1998; 65(2): 314 - 318.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. A. Schmid, P. Vogt, R. Stocker, M. Zalunardo, E. W. Russi, and W. Weder
Lung volume reduction surgery for a patient receiving mechanicalventilation after a complex cardiac operation
J. Thorac. Cardiovasc. Surg., January 1, 1998; 115(1): 236 - 237.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. Argenziano, B. Thomashow, P. A. Jellen, E. A. Rose, K. M. Steinglass, M. E. Ginsburg, and L. A. Gorenstein
Functional Comparison of Unilateral Versus Bilateral Lung Volume Reduction Surgery
Ann. Thorac. Surg., August 1, 1997; 64(2): 321 - 326.
[Abstract] [Full Text]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. D. BECKER, Y. M. BERKMEN, J. H. M. AUSTIN, I. K. MUN, B. M. ROMNEY, A. ROZENSHTEIN, P. A. JELLEN, C. K. YIP, B. THOMASHOW, and M. E. GINSBURG
Lung Volumes before and after Lung Volume Reduction Surgery . Quantitative CT Analysis
Am. J. Respir. Crit. Care Med., May 1, 1997; 157(5): 1593 - 1599.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
W. Wisser, E. Tschernko, O. Senbaklavaci, M. Kontrus, T. Wanke, E. Wolner, and W. Klepetko
Functional Improvement After Volume Reduction: Sternotomy Versus Videoendoscopic Approach
Ann. Thorac. Surg., March 1, 1997; 63(3): 822 - 827.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1996 by The Society of Thoracic Surgeons.