ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Richard J. Novick
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Novick, R. J.
Right arrow Articles by Lee, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Novick, R. J.
Right arrow Articles by Lee, J.

Ann Thorac Surg 1996;62:302-314
© 1996 The Society of Thoracic Surgeons

Current Review

Lung Preservation: The Importance of Endothelial and Alveolar Type II Cell Integrity

Richard J. Novick, MD, Kenneth E. Gehman, MD, Imtiaz S. Ali, MD, John Lee, MD

Transplantation-Immunobiology Group, Robarts Research Institute, and Division of Cardiovascular-Thoracic Surgery, London Health Sciences Centre, London, Ontario, Canada

The practice of lung transplantation is constrained by a shortage of suitable donor organs. Furthermore, even "optimal" donor lung grafts are at risk of significant dysfunction perioperatively. Significant insights into the cellular and molecular mechanisms of pulmonary ischemia-reperfusion injury have occurred since the publication of previous reviews on lung preservation 3 to 4 years ago. Recent evidence indicates that the endothelium plays an essential role in regulating the dynamic interaction between pulmonary vasodilatation and vasoconstriction and is a major target during lung injury. In addition, the composition, function, and metabolism of pulmonary surfactant produced by alveolar type II cells are increasingly being recognized as important factors in pulmonary ischemia-reperfusion injury. We hypothesize that reperfusion after a period of pulmonary ischemia results in significant endothelial and alveolar type II cell dysfunction and that an important strategy in lung preservation is to preserve the integrity of these cells in the face of this injury. Given the persistent shortage of lungs available for transplantation, laboratory studies need to focus also on the "rescue" of compromised donor lungs that would have been previously regarded as unsuitable. Importantly, innovative work from the laboratory needs to be translated into clinical practice via prospective, randomized trials to ensure that the prevalence of postoperative lung graft dysfunction is reduced and the shortage of lung grafts for transplantation is alleviated.




This article has been cited by other articles:


Home page
 Eur Respir JHome page
C. Muhlfeld, I-M. Schaefer, L. Becker, C. Bussinger, M. Vollroth, A. Bosch, R. Nagib, N. Madershahian, J. Richter, T. Wahlers, et al.
Pre-ischaemic exogenous surfactant reduces pulmonary injury in rat ischaemia/reperfusion
Eur. Respir. J., March 1, 2009; 33(3): 625 - 633.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. Gentry, J. Taormina, R. B. Pyles, L. Yeager, M. Kirtley, V. L. Popov, G. Klimpel, and T. Eaves-Pyles
Role of Primary Human Alveolar Epithelial Cells in Host Defense against Francisella tularensis Infection
Infect. Immun., August 1, 2007; 75(8): 3969 - 3978.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
P. A. Thistlethwaite, M. M. Madani, A. D. Kemp, M. Hartley, W. R. Auger, and S. W. Jamieson
Venovenous Extracorporeal Life Support After Pulmonary Endarterectomy: Indications, Techniques, and Outcomes
Ann. Thorac. Surg., December 1, 2006; 82(6): 2139 - 2145.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
E. Koletsis, A. Chatzimichalis, E. Apostolakis, K. Kokkinis, V. Fotopoulos, M. Melachrinou, M. Chorti, J. Crockett, E. Marinos, I. Bellenis, et al.
In Situ Cooling in a Lung Hilar Clamping Model of Ischemia-Reperfusion Injury
Experimental Biology and Medicine, September 1, 2006; 231(8): 1410 - 1420.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
H. B. Bittner, M. Richter, T. Kuntze, A. Rahmel, P. Dahlberg, M. Hertz, and F. W. Mohr
Aprotinin decreases reperfusion injury and allograft dysfunction in clinical lung transplantation
Eur. J. Cardiothorac. Surg., February 1, 2006; 29(2): 210 - 215.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. A. Belperio, M. P. Keane, M. D. Burdick, B. N. Gomperts, Y. Y. Xue, K. Hong, J. Mestas, D. Zisman, A. Ardehali, R. Saggar, et al.
CXCR2/CXCR2 Ligand Biology during Lung Transplant Ischemia-Reperfusion Injury
J. Immunol., November 15, 2005; 175(10): 6931 - 6939.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
B. Gohrbandt, S. P. Sommer, S. Fischer, J. M. Hohlfeld, G. Warnecke, A. Haverich, and M. Strueber
Iloprost to improve surfactant function in porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution
J. Thorac. Cardiovasc. Surg., January 1, 2005; 129(1): 80 - 86.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R.-Z. Zhang, Q. Yang, A. P. C. Yim, and G.-W. He
Alteration of cellular electrophysiologic properties in porcine pulmonary microcirculation after preservation with University of Wisconsin and Euro-Collins solutions
Ann. Thorac. Surg., June 1, 2004; 77(6): 1944 - 1950.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
E. Yildirim, E. Kaptanoglu, K. Ozisik, E. Beskonakli, O. Okutan, M. F. Sargon, K. Kilinc, and U. Sakinci
Ultrastructural changes in pneumocyte type II cells following traumatic brain injury in rats
Eur. J. Cardiothorac. Surg., April 1, 2004; 25(4): 523 - 529.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
I. Friedrich, J. Borgermann, F. H. Splittgerber, M. Brinkmann, J. C. Reidemeister, R. E. Silber, W. Seeger, R. Schmidt, and A. Gunther
Bronchoscopic surfactant administration preserves gas exchange and pulmonary compliance after single lung transplantation in dogs
J. Thorac. Cardiovasc. Surg., February 1, 2004; 127(2): 335 - 343.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
A. Ardehali, H. Laks, H. Russell, M. Levine, R. Shpiner, S. Lackey, and D. Ross
Modified reperfusion and ischemia-reperfusion injury in human lung transplantation
J. Thorac. Cardiovasc. Surg., December 1, 2003; 126(6): 1929 - 1934.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
C.L. Lau and G.A. Patterson
Current status of lung transplantation
Eur. Respir. J., November 16, 2003; 22(47_suppl): 57s - 64s.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
C. Jayle, P. Corbi, M. Eugene, M. Carretier, W. Hebrard, E. Menet, and T. Hauet
Beneficial effect of polyethylene glycol in lung preservation: early evaluation by proton nuclear magnetic resonance spectroscopy
Ann. Thorac. Surg., September 1, 2003; 76(3): 896 - 902.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
I. Kutschka, S. P. Sommer, J. M. Hohlfeld, G. Warnecke, M. Morancho, S. Fischer, A. Haverich, M. Struber, and the Hannover Thoracic Transplant Program
In-situ topical cooling of lung grafts: early graft function and surfactant analysis in a porcine single lung transplant model
Eur. J. Cardiothorac. Surg., September 1, 2003; 24(3): 411 - 419.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
W. Zou, Q. Yang, A. P. C. Yim, and G.-W. He
Impaired endothelium-derived hyperpolarizing factor-mediated relaxation in porcine pulmonary microarteries after cold storage with Euro-Collins and University of Wisconsin solutions
J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 208 - 215.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. Sugita, P. Ferraro, A. Dagenais, M.-E. Clermont, P. Barbry, R. P. Michel, and Y. Berthiaume
Alveolar Liquid Clearance and Sodium Channel Expression Are Decreased in Transplanted Canine Lungs
Am. J. Respir. Crit. Care Med., May 15, 2003; 167(10): 1440 - 1450.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
E. Koletsis, A. Chatzimichalis, V. Fotopoulos, K. Kokkinis, E. Papadimitriou, D. Tiniakos, E. Marinos, I. Bellenis, and D. Dougenis
Donor Lung Pretreatment with Surfactant in Experimental Transplantation Preserves Graft Hemodynamics and Alveolar Morphology
Experimental Biology and Medicine, May 1, 2003; 228(5): 540 - 545.
[Abstract] [Full Text] [PDF]

Home page
 PerfusionHome page
F. R Rega, E. J Vandezande, N. C Jannis, G. M Verleden, T. E Lerut, and D. E. Van Raemdonck
The role of leukocyte depletion in ex vivo evaluation of pulmonary grafts from (non-)heart-beating donors
Perfusion, January 1, 2003; 18(1_suppl): 13 - 21.
[Abstract] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
S. M. Fiser, C. G. Tribble, A. K. Kaza, S. M. Long, J. A. Kern, D. C. Cassada, J. Linden, J. Rieger, V. E. Laubach, A. Matisoff, et al.
Adenosine A2A receptor activation decreases reperfusion injury associated with high-flow reperfusion
J. Thorac. Cardiovasc. Surg., November 1, 2002; 124(5): 973 - 978.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
L. B. Ware, X. Fang, Y. Wang, T. Sakuma, T. S. Hall, and M. A. Matthay
Lung Edema Clearance: 20 Years of Progress: Selected Contribution: Mechanisms that may stimulate the resolution of alveolar edema in the transplanted human lung
J Appl Physiol, November 1, 2002; 93(5): 1869 - 1874.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
G. Warnecke, M. Struber, J. M. Hohlfeld, J. Niedermeyer, S. P. Sommer, and A. Haverich
Pulmonary preservation with Bretscheider's HTK and Celsior solution in minipigs
Eur. J. Cardiothorac. Surg., June 1, 2002; 21(6): 1073 - 1079.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
A. G. Duarte and S. Lick
Predicting Outcome in Primary Graft Failure
Chest, June 1, 2002; 121(6): 1736 - 1738.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
T. Fukuse, T. Hirata, M. Omasa, and H. Wada
Effect of Adenosine Triphosphate-Sensitive Potassium Channel Openers on Lung Preservation
Am. J. Respir. Crit. Care Med., June 1, 2002; 165(11): 1511 - 1515.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. M. Fiser, C. G. Tribble, S. M. Long, A. K. Kaza, J. A. Kern, D. R. Jones, M. K. Robbins, and I. L. Kron
Ischemia-reperfusion injury after lung transplantation increases risk of late bronchiolitis obliterans syndrome
Ann. Thorac. Surg., April 1, 2002; 73(4): 1041 - 1048.
[Abstract] [Full Text] [PDF]

Home page
 PerfusionHome page
B. S Allen
The role of leukodepletion in limiting ischemia/reperfusion damage in the heart, lung and lower extremity
Perfusion, March 1, 2002; 17(2_suppl): 11 - 22.
[Abstract] [PDF]

Home page
 PerfusionHome page
M. Kurusz, J. D Roach Jr, R. A Vertrees, M. K Girouard, and S. D Lick
Leukocyte filtration in lung transplantation
Perfusion, March 1, 2002; 17(2_suppl): 63 - 67.
[Abstract] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
K. NOWAK, M. KAMLER, M. BOCK, J. MOTSCH, S. HAGL, H. JAKOB, and M.-M. GEBHARD
Bronchial Artery Revascularization Affects Graft Recovery after Lung Transplantation
Am. J. Respir. Crit. Care Med., January 15, 2002; 165(2): 216 - 220.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. J. Novick
Innovative techniques to enhance lung preservation
J. Thorac. Cardiovasc. Surg., January 1, 2002; 123(1): 3 - 5.
[Full Text] [PDF]

Home page
 J Intensive Care MedHome page
M. M. Chakinala, M. H. Kollef, and E. P. Trulock
Critical Care Aspects of Lung Transplant Patients
J Intensive Care Med, January 1, 2002; 17(1): 8 - 33.
[Abstract] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Struber, J. M. Hohlfeld, T. Kofidis, G. Warnecke, J. Niedermeyer, S. P. Sommer, and A. Haverich
Surfactant function in lung transplantation after 24 hours of ischemia: Advantage of retrograde flush perfusion for preservation
J. Thorac. Cardiovasc. Surg., January 1, 2002; 123(1): 98 - 103.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
A. Salvatierra, R. Guerrero, M. Rodriguez, A. Alvarez, F. Soriano, R. Lopez-Pedrera, R. Ramirez, J. Carracedo, F. Lopez-Rubio, J. Lopez-Pujol, et al.
Antithrombin III Prevents Early Pulmonary Dysfunction After Lung Transplantation in the Dog
Circulation, December 11, 2001; 104(24): 2975 - 2980.
[Abstract] [Full Text] [PDF]

Home page
 Arch SurgHome page
C. D. Raeburn, J. C. Cleveland Jr, M. A. Zimmerman, and A. H. Harken
Organ Preconditioning
Arch Surg, November 1, 2001; 136(11): 1263 - 1266.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
Y. Sunose, I. Takeyoshi, H. Tsutsumi, S. Ohwada, N. Oriuchi, K. Matsumoto, and Y. Morishita
Effect of a cyclooxygenase-2 inhibitor, FK3311, in a canine lung transplantation model
Ann. Thorac. Surg., October 1, 2001; 72(4): 1165 - 1171.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
S. Hillinger, P. Sandera, G. L. Carboni, U. Stammberger, M. Zalunardo, G. Schoedon, and R. A. Schmid
Survival and graft function in a large animal lung transplant model after 30 h preservation and substitution of the nitric oxide pathway
Eur. J. Cardiothorac. Surg., September 1, 2001; 20(3): 508 - 513.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
S. M. Fiser, C. G. Tribble, S. M. Long, A. K. Kaza, J. T. Cope, V. E. Laubach, J. A. Kern, and I. L. Kron
Lung transplant reperfusion injury involves pulmonary macrophages and circulating leukocytes in a biphasic response
J. Thorac. Cardiovasc. Surg., June 1, 2001; 121(6): 1069 - 1075.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. M. Fiser, C. G. Tribble, S. M. Long, A. K. Kaza, J. A. Kern, and I. L. Kron
Pulmonary macrophages are involved in reperfusion injury after lung transplantation
Ann. Thorac. Surg., April 1, 2001; 71(4): 1134 - 1139.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
M. Struber, M. Wilhelmi, W. Harringer, J. Niedermeyer, M. Anssar, A. Kunsebeck, J. D. Schmitto, and A. Haverich
Flush perfusion with low potassium dextran solution improves early graft function in clinical lung transplantation
Eur. J. Cardiothorac. Surg., February 1, 2001; 19(2): 190 - 194.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. J. FISHER, S. C. DONNELLY, N. HIRANI, C. HASLETT, R. M. STRIETER, J. H. DARK, and P. A. CORRIS
Elevated Levels of Interleukin-8 in Donor Lungs Is Associated with Early Graft Failure after Lung Transplantation
Am. J. Respir. Crit. Care Med., January 1, 2001; 163(1): 259 - 265.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
S. Demertzis, M. Scherer, F. Langer, A. Dwenger, B. Hausen, and H.-J. Schafers
Ascorbic acid for amelioration of reperfusion injury in a lung autotransplantation model in sheep
Ann. Thorac. Surg., November 1, 2000; 70(5): 1684 - 1689.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. A. Cardella, S. Keshavjee, E. Mourgeon, S. D. Cassivi, S. Fischer, N. Isowa, A. Slutsky, and M. Liu
A novel cell culture model for studying ischemia-reperfusion injury in lung transplantation
J Appl Physiol, October 1, 2000; 89(4): 1553 - 1560.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
K. M. Vural and M. C. Oz
Endothelial adhesivity, pulmonary hemodynamics and nitric oxide synthesis in ischemia-reperfusion
Eur. J. Cardiothorac. Surg., September 1, 2000; 18(3): 348 - 352.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Struber, J. M. Hohlfeld, S. Fraund, P. Kim, G. Warnecke, and A. Haverich
Low-potassium dextran solution ameliorates reperfusion injury of the lung and protects surfactant function
J. Thorac. Cardiovasc. Surg., September 1, 2000; 120(3): 566 - 572.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
S. D. Ross, I. L. Kron, J. J. Gangemi, K. S. Shockey, M. Stoler, J. A. Kern, C. G. Tribble, and V. E. Laubach
Attenuation of lung reperfusion injury after transplantation using an inhibitor of nuclear factor-kappa B
Am J Physiol Lung Cell Mol Physiol, September 1, 2000; 279(3): L528 - L536.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. C. King, O. A.R. Binns, F. Rodriguez, R. C. Kanithanon, T. M. Daniel, W. D. Spotnitz, C. G. Tribble, and I. L. Kron
Reperfusion injury significantly impacts clinical outcome after pulmonary transplantation
Ann. Thorac. Surg., June 1, 2000; 69(6): 1681 - 1685.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. FEHRENBACH, M. OCHS, T. WARNECKE, T. WAHLERS, T. WITTWER, A. SCHMIEDL, S. ELKI, D. MEYER, J. RICHTER, and H. FEHRENBACH
Beneficial Effect of Lung Preservation Is Related to Ultrastructural Integrity of Tubular Myelin after Experimental Ischemia and Reperfusion
Am. J. Respir. Crit. Care Med., June 1, 2000; 161(6): 2058 - 2065.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
F. Loehe, C. Mueller, T. Annecke, A. Siebel, I. Bittmann, K. F.W. Messmer, and F. W. Schildberg
Pulmonary graft function after long-term preservation of non-heart-beating donor lungs
Ann. Thorac. Surg., May 1, 2000; 69(5): 1556 - 1562.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. D. Lick, P. S. Brown Jr, M. Kurusz, R. A. Vertrees, C. K. McQuitty, and W. E. Johnston
Technique of controlled reperfusion of the transplanted lung in humans
Ann. Thorac. Surg., March 1, 2000; 69(3): 910 - 912.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. O. Halldorsson, M. T. Kronon, B. S. Allen, S. Rahman, and T. Wang
Lowering reperfusion pressure reduces the injury after pulmonary ischemia
Ann. Thorac. Surg., January 1, 2000; 69(1): 198 - 203.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. M. Vural, H. Liao, M. C. Oz, and D. J. Pinsky
Effects of mast cell membrane stabilizing agents in a rat lung ischemia-reperfusion model
Ann. Thorac. Surg., January 1, 2000; 69(1): 228 - 232.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. L. Featherstone, D. J. Chambers, and F. J. Kelly
Ischemic preconditioning enhances recovery of isolated rat lungs after hypothermic preservation
Ann. Thorac. Surg., January 1, 2000; 69(1): 237 - 242.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. Hillinger, R. A. Schmid, P. Sandera, U. Stammberger, D. Schneiter, G. Schoedon, and W. Weder
8-Br-cGMP is superior to prostaglandin e1 for lung preservation
Ann. Thorac. Surg., October 1, 1999; 68(4): 1138 - 1142.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
G. Asimakopoulos, P. L.C. Smith, C. P. Ratnatunga, and K. M. Taylor
Lung injury and acute respiratory distress syndrome after cardiopulmonary bypass
Ann. Thorac. Surg., September 1, 1999; 68(3): 1107 - 1115.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. OCHS, I. NENADIC, A. FEHRENBACH, J. M. ALBES, T. WAHLERS, J. RICHTER, and H. FEHRENBACH
Ultrastructural Alterations in Intraalveolar Surfactant Subtypes after Experimental Ischemia and Reperfusion
Am. J. Respir. Crit. Care Med., August 1, 1999; 160(2): 718 - 724.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
S. D. Ross, C. G. Tribble, J. R. Gaughen Jr, K. S. Shockey, P. E. Parrino, and I. L. Kron
Reduced neutrophil infiltration protects against lung reperfusion injury after transplantation
Ann. Thorac. Surg., May 1, 1999; 67(5): 1428 - 1433.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
D. E.M. Van Raemdonck, N. C.P. Jannis, P. R.J. De Leyn, W. J. Flameng, and T. E. Lerut
Alveolar expansion itself but not continuous oxygen supply enhances postmortem preservation of pulmonary grafts
Eur. J. Cardiothorac. Surg., April 1, 1999; 13(4): 431 - 441.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. L. Featherstone, F. J. Kelly, and D. J. Chambers
Theophylline improves functional recovery of isolated rat lungs after hypothermic preservation
Ann. Thorac. Surg., March 1, 1999; 67(3): 798 - 803.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
L. B. WARE, J. A. GOLDEN, W. E. FINKBEINER, and M. A. MATTHAY
Alveolar Epithelial Fluid Transport Capacity in Reperfusion Lung Injury after Lung Transplantation
Am. J. Respir. Crit. Care Med., March 1, 1999; 159(3): 980 - 988.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
R. C. King, V. E. Laubach, R. C. Kanithanon, A. M. Kron, P. E. Parrino, K. S. Shockey, C. G. Tribble, and I. L. Kron
Preservation with 8-bromo-cyclic GMP improves pulmonary function after prolonged ischemia
Ann. Thorac. Surg., November 1, 1998; 66(5): 1732 - 1738.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. O. Halldorsson, M. Kronon, B. S. Allen, S. Rahman, T. Wang, M. Layland, and D. Sidle
Controlled reperfusion prevents pulmonary injury after 24 hours of lung preservation
Ann. Thorac. Surg., September 1, 1998; 66(3): 877 - 885.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. Takigami, S. Sasaki, N. Shiiya, M. Kawasaki, E. Takeuchi, and K. Yasuda
Evaluation of 18-hour lung preservation with oxygenated blood for optimal oxygen delivery
Ann. Thorac. Surg., August 1, 1998; 66(2): 362 - 366.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. Tonz, D. Bachmann, D. Mettler, and G. Kaiser
Pulmonary function after one-lung ventilation in newborns: the basis for neonatal thoracoscopy
Ann. Thorac. Surg., August 1, 1998; 66(2): 542 - 546.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
A. Halldorsson, M. Kronon, B. S. Allen, K. S. Bolling, T. Wang, S. Rahman, H. Feinberg, and R. S. Hartz
Controlled Reperfusion After Lung Ischemia: Implications For Improved Function After Lung Transplantation
J. Thorac. Cardiovasc. Surg., February 1, 1998; 115(2): 415 - 425.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. J. Novick, L. W. Stitt, K. Al-Kattan, W. Klepetko, H.-J. Schafers, J.-P. Duchatelle, A. Khaghani, R. L. Hardesty, G. A. Patterson, and M. H. Yacoub
Pulmonary Retransplantation: Predictors of Graft Function and Survival in 230 Patients
Ann. Thorac. Surg., January 1, 1998; 65(1): 227 - 234.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
L. E. Hinman, G. J. Beilman, K. E. Groehler, and P. J. Sammak
Wound-induced calcium waves in alveolar type II cells
Am J Physiol Lung Cell Mol Physiol, December 1, 1997; 273(6): L1242 - L1248.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. C. King, O. A. R. Binns, R. C. Kanithanon, P. E. Parrino, T. B. Reece, J. D. Maliszewskyj, K. S. Shockey, C. G. Tribble, and I. L. Kron
Acellular Low-Potassium Dextran Preserves Pulmonary Function After 48 Hours of Ischemia
Ann. Thorac. Surg., September 1, 1997; 64(3): 795 - 800.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
D. E. M. Van Raemdonck, N. C. P. Jannis, F. R. L. Rega, P. R. J. De Leyn, W. J. Flameng, and T. E. Lerut
Extended Preservation of Ischemic Pulmonary Graft by Postmortem Alveolar Expansion
Ann. Thorac. Surg., September 1, 1997; 64(3): 801 - 808.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
B. Hausen, P. Mueller, M. Bahra, R. Ramsamooj, R. E. Morris, and C. W. Hewitt
Donor Treatment With the Lazeroid U74389G Reduces Ischemia-Reperfusion Injury in a Rat Lung Transplant Model
Ann. Thorac. Surg., September 1, 1997; 64(3): 814 - 820.
[Abstract] [Full Text]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
A. Watanabe, N. Kawaharada, K. Kusajima, S. Komatsu, T. Abe, and H. Takahashi
INFLUENCE OF OXYGEN IN INFLATION GAS DURING LUNG ISCHEMIA ON ISCHEMIA-REPERFUSION INJURY
J. Thorac. Cardiovasc. Surg., September 1, 1997; 114(3): 332 - 338.
[Abstract] [Full Text]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
B. Hausen, R. Rohde, C. W. Hewitt, F. Schroeder, M. Beuke, R. Ramsamooj, H.-J. Schafers, Sponsor:, and H.-G. Borst
EXOGENOUS SURFACTANT TREATMENT BEFORE AND AFTER SIXTEEN HOURS OF ISCHEMIA IN EXPERIMENTAL LUNG TRANSPLANTATION
J. Thorac. Cardiovasc. Surg., June 1, 1997; 113(6): 1050 - 1058.
[Abstract] [Full Text]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
S. Murakami, E. A. Bacha, P. Herve, H. Detruit, A. R. Chapelier, P. G. Dartevelle, G.-M. Mazmanian, and The Paris-Sud University Lung Transplantation Grou
INHALED NITRIC OXIDE AND PENTOXIFYLLINE IN RAT LUNG TRANSPLANTATION FROM NON-HEART-BEATING DONORS
J. Thorac. Cardiovasc. Surg., May 1, 1997; 113(5): 821 - 829.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
R. C. King, O. A. R. Binns, R. C. Kanithanon, J. T. Cope, R. L. Chun, K. S. Shockey, C. G. Tribble, and I. L. Kron
Low-Dose Sodium Nitroprusside Reduces Pulmonary Reperfusion Injury
Ann. Thorac. Surg., May 1, 1997; 63(5): 1398 - 1404.
[Abstract] [Full Text]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. J. Novick, A. A. Gilpin, K. E. Gehman, I. S. Ali, R. A. W. Veldhuizen, J. Duplan, L. Denning, F. Possmayer, D. Bjarneson, and J. F. Lewis
MITIGATION OF INJURY IN CANINE LUNG GRAFTS BY EXOGENOUS SURFACTANT THERAPY
J. Thorac. Cardiovasc. Surg., February 1, 1997; 113(2): 342 - 353.
[Abstract] [Full Text]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. J. Novick, L. Stitt, H.-J. Schafers, B. Andreassian, J.-P. Duchatelle, W. Klepetko, R. L. Hardesty, A. Frost, and G. A. Patterson
PULMONARY RETRANSPLANTATION: DOES THE INDICATION FOR OPERATION INFLUENCE POSTOPERATIVE LUNG FUNCTION?
J. Thorac. Cardiovasc. Surg., December 1, 1996; 112(6): 1504 - 1514.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1996 by The Society of Thoracic Surgeons.