ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Schmidt, H.
Right arrow Articles by Nielsen, S. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schmidt, H.
Right arrow Articles by Nielsen, S. L.

Ann Thorac Surg 1996;62:105-108
© 1996 The Society of Thoracic Surgeons

Original Articles: Cardiovascular

Autotransfused Shed Mediastinal Blood Has Normal Erythrocyte Survival

Henrik Schmidt, MD, Jens Otto Lund, MD, Steen Levin Nielsen, MD

Department of Anaesthesiology, Gentofte Hospital, and Department of Clinical Physiology and Nuclear Medicine, Gentofte and Herlev Hospitals, University of Copenhagen, Hellerup, Denmark

Accepted for publication February 23, 1996.

Background. Autotransfusion of shed mediastinal blood may reduce the need for homologous blood transfusions in cardiac surgery. In an earlier study we have shown that the red blood cells (RBCs) of shed mediastinal blood have a normal membrane stability (osmotic fragility) compared with circulating RBCs after coronary artery bypass grafting and better than stored RBCs. This indicates that RBCs in shed mediastinal blood are not damaged further during salvage. It remains to be determined how autotransfusion affects the survival of RBCs from shed mediastinal blood.

Methods. We performed a prospective, randomized, and controlled study involving 26 patients having elective, uncomplicated coronary artery bypass grafting. Dual-isotope labeling technique (chromium 51 and technetium 99m) was used to investigate the 24-hour survival of RBCs from shed mediastinal blood and RBCs from circulating blood, and to estimate the mean survival time of RBCs.

Results. There was no significant difference between the 24-hour survival of shed mediastinal RBCs and circulating RBCs. The estimated mean cell lifespan was 20.5 days (range, 11.6 to 29.0 days) for shed mediastinal RBCs and 22.7 days (range, 14.4 to 36.2 days) for circulating RBCs.

Conclusions. The survival of RBCs from shed mediastinal blood after autotransfusion is comparable with the survival of RBCs in the patients' circulating blood.




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
G. J. Murphy, S. M. Allen, J. Unsworth-White, C. T. Lewis, and M. J. R. Dalrymple-Hay
Safety and efficacy of perioperative cell salvage and autotransfusion after coronary artery bypass grafting: a randomized trial
Ann. Thorac. Surg., May 1, 2004; 77(5): 1553 - 1559.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
H. I. Flom-Halvorsen, E. Ovrum, G. Tangen, F. Brosstad, M.-A. L. Ringdal, and R. Oystese
AUTOTRANSFUSION IN CORONARY ARTERY BYPASS GRAFTING: DISPARITY IN LABORATORY TESTS AND CLINICAL PERFORMANCE
J. Thorac. Cardiovasc. Surg., October 1, 1999; 118(4): 610 - 617.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1996 by The Society of Thoracic Surgeons.