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Ann Thorac Surg 1996;61:1231-1235
© 1996 The Society of Thoracic Surgeons

Original Article: Cardiovascular

Efficacy and Safety of a Percutaneous Right Ventricular Assist System

Mitsuhiro Yano, MD, Toshio Onitsuka, MDPhD, Koichiro Shibata, MDPhD, Yasunori Koga, MDPhD

Second Department of Surgery, Miyazaki Medical College, Miyazaki, Japan

Accepted for publication December 29, 1995.

Background. Mechanical right ventricular assistance is necessary in the management of profound right ventricular failure resistant to medical therapy. Conventional right ventricular assistance requires a thoracotomy. We developed a technique for assisting the failing right ventricle without thoracotomy.

Methods. We implanted the percutaneous right ventricular assist system in animals to test its feasibility and safety. A feasibility study was performed in a right ventricular failure model using 12 open chest dogs, and we examined the effects of the system hemodynamically. Next, the system was implanted into 6 goats and driven for 2 to 8 days.

Results. Institution of the percutaneous right ventricular assist system revealed overall hemodynamic improvement on right ventricular failure in dogs. In the goat experiment, no animal died from cannula-related complications. No damage to the intracardiac structures and no pulmonary edema were seen. Plasma free hemoglobin concentration did not exceed 10 mg/dL.

Conclusions. The percutaneous right ventricular assist system is safe and effective in the management of right ventricular failure.




This article has been cited by other articles:


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G. J. Endo, K. Kojima, K. Nakamura, Y. Matsuzaki, and T. Onitsuka
Nitric oxide inhalation prompts weaning from the right ventricular assist device: Evaluation under continuous-flow biventricular assistance
J. Thorac. Cardiovasc. Surg., October 1, 2002; 124(4): 739 - 749.
[Abstract] [Full Text] [PDF]


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