| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 1995;60:1783-1789
© 1995 The Society of Thoracic Surgeons
Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians & Surgeons, New York, New York
Accepted for publication August 11, 1995.
Background. As long-term survival after cardiac transplantation improves, neoplastic complications are increasingly being discovered. Although lymphoproliferative disorders predominate, the incidence and clinical spectrum of solid tumors in a uniform population of heart transplant recipients remains uncertain.
Methods. We reviewed our experience with 712 patients who underwent cardiac transplantation. Clinical charts were reviewed and telephone interviews were conducted, when possible.
Results. De novo solid malignancies were identified in 3.3% of patients at risk (21 of 633 patients). Twenty patients were male; mean age was 51.5 ± 8.6 years. Most patients reported a significant smoking history. Pulmonary, urologic, and Kaposi's sarcoma were the most common malignancies identified. Mean interval from transplantation to diagnosis was 35 months. Six patients were diagnosed within 6 months of transplantation. One-year and 5-year survival after transplantation were 90% and 49%, respectively. One-year and 3-year survival after cancer diagnosis were 60% and 52%, respectively.
Conclusions. De novo solid malignancy after transplantation occurred with about half the frequency of lymphoproliferative disorders. A striking male predominance was noted. The interval from transplantation to the appearance of cancer is variable, and no clustering was identified. A significant smoking history warrants aggressive search for occult malignancy during pretransplantation evaluation of potential heart recipients.
Related Article
Ann. Thorac. Surg. 1995 60: 1559-1560.
This article has been cited by other articles:
|
|
 |
|
  P. Bagan, F. L. P. Barthes, and M. Riquet Prognosis of Lung Cancer in Heart Transplant Recipient Ann. Thorac. Surg., January 1, 2006; 81(1): 409 - 409. [Full Text] [PDF]
|
|
|
|
|
|
K. Potaris, B. Radovancevic, C. D. Thomas, I. Gregoric, A. A. Vaporciyan, S. A. Riggs, R. Radovancevic, W. K. Vaughn, and O.H. Frazier Lung Cancer After Heart Transplantation: A 17-Year Experience Ann. Thorac. Surg., March 1, 2005; 79(3): 980 - 983. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Bagan, J. Assouad, P. Berna, R. Souilamas, F. Le Pimpec Barthes, and M. Riquet Immediate and Long-Term Survival After Surgery for Lung Cancer in Heart Transplant Recipients Ann. Thorac. Surg., February 1, 2005; 79(2): 438 - 442. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Ahmed, M. B. Marshall, J. C. Kucharczuk, L. R. Kaiser, and J. B. Shrager Lung Cancer in Transplant Recipients: A Single-Institution Experience Arch Surg, August 1, 2004; 139(8): 902 - 906. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Lenner, M. L. Padilla, A. S. Teirstein, A. Gass, and G. J. Schilero Pulmonary Complications in Cardiac Transplant Recipients Chest, August 1, 2001; 120(2): 508 - 513. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Rinaldi, C. Pellegrini, A. M. D'Armini, M. Aiello, M. Negri, E. Arbustini, G. Ippoliti, and M. Vigano Neoplastic disease after heart transplantation: single center experience Eur. J. Cardiothorac. Surg., May 1, 2001; 19(5): 696 - 701. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Penn Solid Tumors in Cardiac Allograft Recipients Ann. Thorac. Surg., December 1, 1995; 60(6): 1559 - 1560. [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
