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Ann Thorac Surg 1995;60:1425-1427
© 1995 The Society of Thoracic Surgeons

Case Reports

Cardiac Transplantation for Hypertrophic Cardiomyopathy Associated With Sengers' Syndrome

Robert C. Robbins, MD, Daniel Bernstein, MD, Gerald J. Berry, MD, Krisa P. VanMeurs, MD, Lorry R. Frankel, MD, Bruce A. Reitz, MD

Departments of Cardiothoracic Surgery, Pediatrics, and Pathology, Stanford University School of Medicine, Stanford, California

Accepted for publication May 18, 1995.

Sengers' syndrome is a rare condition consisting of congenital cataracts, mitochondrial myopathy, and hypertrophic cardiomyopathy. The syndrome is transmitted in an autosomal recessive pattern. Progressive cardiac failure is the cause of death in most patients. This report describes cardiac transplantation for the treatment of the cardiomyopathy associated with Sengers' syndrome.




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