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Ann Thorac Surg 1995;60:839-842
© 1995 The Society of Thoracic Surgeons
Department of Cardiothoracic Surgery, The Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina, USA
* Address reprint requests to Dr Hammon, Department of Cardiothoracic Surgery, Bowman Gray School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157-1096.
In an era when essentially no congenital heart defect is considered inoperable, it is reasonable to carefully consider the essentials of neonatal myocardial physiology and biochemistry, especially comparisons between immature and adult myocardial responses to ischemia. Because many special clinical interactions dramatically affect myocardial protection, great care must be taken to analyze each case carefully with protection strategies in mind. Finally, cardioplegia composition and delivery are now quite similar to those used in adults, with new equipment facilitating delivery. Research is underway to supplement protection in immature hearts severely injured by adverse preoperative conditions.
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