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Ann Thorac Surg 1995;60:217-222
© 1995 The Society of Thoracic Surgeons

Current Reviews

Primary Malignant Melanoma of the Esophagus

Axel W. Joob, MD, G. Kenneth Haines, III, MD, Merrill S. Kies, MD, Thomas W. Shields, MD

Departments of Surgery, Pathology, and Medicine, Northwestern University Medical School, Chicago, Illinois

Primary malignant melanoma of the esophagus is a rare disease. A case is reported and the newer diagnostic techniques of immunohistologic identification of the tumor by positive reaction to the HMB-45 antigen, as well as immunoscintigraphy with Technetium-99m–labeled melanoma monoclonal antigen for the demonstration of distant metastasis, is presented. A current review of the literature on this uncommon tumor is presented, and treatment options are discussed. A total esophagectomy remains the treatment of choice. Four long-term (>5 years) survivors after adequate surgical removal have been recorded in the literature.




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