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Lawrence L. Creswell
Michael J. Moulton
James L. Cox
Michael Rosenbloom
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Ann Thorac Surg 1995;60:19-26
© 1995 The Society of Thoracic Surgeons


Articles

Revascularization after acute myocardial infarction

MD Lawrence L. Creswell, MD Michael J. Moulton, MD James L. Cox, MD Michael Rosenbloom*

Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine and Barnes Hospital, St. Louis, Missouri, USA

* Address reprint requests to Dr Rosenbloom, Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, 3108 Queeny Tower, Barnes Hospital, One Barnes Hospital Plaza, St. Louis, MO 63110.
Presented at the Thirty-first Annual Meeting of the Society of Thoracic Surgeons, Palm Springs, CA, Jan 30–Feb 1, 1995.

Background.: The optimal timing for coronary artery bypass grafting (CABG) after acute myocardial infarction (MI) remains controversial.

Methods.: We examined our experience retrospectively in 3,942 patients who underwent CABG between 1986 and 1993, including 2,296 patients after acute MI.

Results.: The operative mortality associated with increasing time intervals between MI and CABG were 9.1%, 8.3%, 5.2%, 6.5%, and 2.9%, for less than 6 hours, 6 hours to 2 days, 2 to 14 days, 2 to 6 weeks, and more than 6 weeks, respectively. In comparison, the operative mortality was 2.5% for patients with no history of acute MI. The incidence of permanent stroke and perioperative MI were greater and the length of postoperative hospitalization was longer for patients undergoing CABG early after MI. For patients undergoing operation electively, however, the operative mortality associated with increasing time intervals between MI and CABG were less, at 0.0%, 3.6%, 2.1%, 6.4%, and 2.1% for less than 6 hours, 6 hours to 2 days, 2 to 14 days, 2 to 6 weeks, and more than 6 weeks, respectively. For patients undergoing CABG within 14 days of MI, the operative mortality was 5.3% for those receiving an intraaortic balloon pump preoperatively for postinfarction angina, but 11.8% for those who underwent urgent/emergent operation without intraaortic balloon pump support.

Conclusions.: Elective CABG can be accomplished with acceptable morbidity and mortality early after acute MI if an elective operation is possible. In addition, the intraaortic balloon pump should be used aggressively in patients with postinfarction angina to allow for elective rather than urgent/emergent operation.




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