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Ann Thorac Surg 1995;59:1345-1350
© 1995 The Society of Thoracic Surgeons
Department of Psychiatry and Behavioral Sciences, Community and Family Medicine, and Anesthesiology, and Duke Heart Center, Duke University Medical Center, Durham, North Carolina
Abstract
This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive decline; (6) statistical analysis; and (7) clinical significance. Implications for further research in the area are discussed.
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