HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): David A. Fullerton David N. Campbell Stephen D. Jones James Jaggers Mary M. Wollmering Frederick L. Grover Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Fullerton, D. A. Articles by Boucek, M. M. Search for Related Content PubMed PubMed Citation Articles by Fullerton, D. A. Articles by Boucek, M. M. Related Collections Related Article

Ann Thorac Surg 1995;59:804-811
© 1995 The Society of Thoracic Surgeons

Heart Transplantation in Children and Young Adults: Early and Intermediate-Term Results

Departments of Surgery and Pediatrics, University of Colorado, Denver, Colorado

The purpose of this article is to report our short- and intermediate-term follow-up of cardiac transplantation for congenital heart disease and cardiomyopathy in children (age greater than 6 months), adolescents, and young adults. Thirty patients (ages 8 months to 24 years) with end-stage heart failure have undergone cardiac transplantation in our program: 12 (40%) for postoperative end-stage heart failure, 9 (30%) as primary treatment for congenital heart disease, 5 (17%) for dilated cardiomyopathy, and 4 (13%) for restrictive/hypertrophic cardiomyopathy. Nineteen patients (63%) had undergone prior operations; 4 patients received transplants for failed Fontan procedures. Induction therapy with antithymocyte therapy was used routinely, and long-term immunosuppression was by cyclosporine and azathioprine alone. Rejection surveillance/diagnosis was based on echocardiographic criteria. Posttransplantation follow-up ranges from 3 to 78 months. Operative mortality was 3.3% (1/30). No patients have been diagnosed with either accelerated allograft atherosclerosis or posttransplantation lymphoproliferative disease. We conclude that cardiac transplantation may be performed with excellent early and intermediate-term results.

Related Article

DISCUSSION
Ann. Thorac. Surg. 1995 59: 811-812. [Extract] [Full Text]

This article has been cited by other articles:

				K. A. Jayakumar, L. J. Addonizio, M. R. Kichuk-Chrisant, M. E. Galantowicz, J. M. Lamour, J. M. Quaegebeur, and D. T. Hsu Cardiac transplantation after the Fontan or Glenn procedure J. Am. Coll. Cardiol., November 16, 2004; 44(10): 2065 - 2072. [Abstract] [Full Text] [PDF]

				M. B. Mitchell, D. N. Campbell, D. Ivy, M. M. Boucek, H. M. Sondheimer, B. Pietra, B. B. Das, and J. R. Coll Evidence of pulmonary vascular disease after heart transplantation for Fontan circulation failure J. Thorac. Cardiovasc. Surg., November 1, 2004; 128(5): 693 - 702. [Abstract] [Full Text] [PDF]

				C. Mavroudis and R. M. Sade The Southern Thoracic Surgical Association 50th anniversary celebration: the impact of STSA pediatric cardiothoracic surgery manuscripts on surgical practice Ann. Thorac. Surg., November 1, 2003; 76(90050): S47 - 67. [Abstract] [Full Text] [PDF]

				J. A. Dearani, A. J. Razzouk, S. R. Gundry, R. E. Chinnock, R. L. Larsen, M. J. del Rio, J. K. Johnston, and L. L. Bailey Pediatric cardiac retransplantation: intermediate-term results Ann. Thorac. Surg., January 1, 2001; 71(1): 66 - 70. [Abstract] [Full Text] [PDF]

				J. M. Lamour, L. J. Addonizio, M. E. Galantowicz, J. M. Quaegebeur, D. M. Mancini, M. R. Kichuk, A. Beniaminovitz, R. E. Michler, A. Weinberg, and D. T. Hsu Outcome After Orthotopic Cardiac Transplantation in Adults With Congenital Heart Disease Circulation, November 9, 1999; 100(90002): II-200 - 205. [Abstract] [Full Text] [PDF]

				K. R. Kanter, V. K.H. Tam, R. N. Vincent, A. R. Cuadrado, A. A. Raviele, and A. M. Berg Current results with pediatric heart transplantation Ann. Thorac. Surg., August 1, 1999; 68(2): 527 - 530. [Abstract] [Full Text] [PDF]

				M. B. Mitchell, D. N. Campbell, D. R. Clarke, D. A. Fullerton, F. L. Grover, M. M. Boucek, B. Pietra, M. Luna, A. L. Shroyer, J. R. Coll, et al. Infant heart transplantation: improved intermediate results J. Thorac. Cardiovasc. Surg., August 1, 1998; 116(2): 242 - 246. [Abstract] [Full Text] [PDF]

				A. J. Razzouk, R. E. Chinnock, J. A. Dearani, S. R. Gundry, and L. L. Bailey Cardiac Retransplantation for Graft Vasculopathy in Children: Should We Continue to Do It? Arch Surg, August 1, 1998; 133(8): 881 - 885. [Abstract] [Full Text] [PDF]

				D. B. McElhinney, V. M. Reddy, P. Moore, and F. L. Hanley Revision of Previous Fontan Connections to Extracardiac or Intraatrial Conduit Cavopulmonary Anastomosis Ann. Thorac. Surg., November 1, 1996; 62(5): 1276 - 1282. [Abstract] [Full Text]

				S. Wan, J.-M. DeSmet, M. Antoine, M. Goldman, J.-L. Vincent, and J.-L. LeClerc Steroid Administration in Heart and Heart-Lung Transplantation: Is the Timing Adequate? Ann. Thorac. Surg., February 1, 1996; 61(2): 674 - 678. [Abstract] [Full Text]