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Ann Thorac Surg 1995;59:759-761
© 1995 The Society of Thoracic Surgeons


Case Reports

Fungal Pulmonary Abscess in an Adult Secondary to Hyperimmunoglobulin E (Job's) Syndrome

R. Alan Hall, MD, Kevin E. Salhany, MD, Elise Lebel, MD, Joseph E. Bavaria, MD, Larry R. Kaiser, MD

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

Accepted for publication July 14, 1994.

Job's syndrome is characterized by recurring bacterial infections of the skin and sinopulmonary tract. Laboratory evaluation reveals consistent elevation of circulating immunoglobulin E levels. The syndrome has been reported as a rare cause of bacterial pulmonary abscess and pneumatocele formation in childhood; here we present a case of cavitating fungal abscess in an adult with Job's syndrome.




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B. Grimbacher, S. M. Holland, J. I. Gallin, F. Greenberg, S. C. Hill, H. L. Malech, J. A. Miller, A. C. O'Connell, and J. M. Puck
Hyper-IgE Syndrome with Recurrent Infections -- An Autosomal Dominant Multisystem Disorder
N. Engl. J. Med., March 4, 1999; 340(9): 692 - 702.
[Abstract] [Full Text] [PDF]




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