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Ann Thorac Surg 1995;59:508-509
© 1995 The Society of Thoracic Surgeons

Case Reports

Heparin-Induced Thrombocytopenia and Heart Operation: Management With Tedelparin

Albert Altés, MD, Rodrigo Martino, MD, Mercè Gari, Maria Lluisa Cámara, MD, Rosa Garín, Juan-Ignacio Casas, MD, Jordi Fontcuberta, PhD

Unitat d'Hemostasia i Trombosi, Servei de Cirurgia Cardíaca, Servei d'Anestèsia i Reanimacio, Hospital de Sant Pau, Barcelona, Spain

Accepted for publication May 26, 1994.

Anticoagulation for cardiopulmonary bypass in the infrequent clinical setting of thrombocytopenia associated with the use of unfractionated heparin is a very serious problem. We describe a case in which a low-molecular-weight heparin (tedelparin) was selected for this purpose based on a platelet aggregation test, permitting adequate anticoagulation during cardiopulmonary bypass for valve replacement. This case report might help establish an adequate anticoagulation protocol when faced with a patient suffering from this condition.




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