| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Ann Thorac Surg 1995;59:137-143
© 1995 The Society of Thoracic Surgeons
Clinic for Cardiovascular Surgery, Institute of Anaesthesiology, Institute of Clinical Immunology, and Institute for Clinical Chemistry, University Hospital, Zurich, Switzerland
Accepted for publication July 22, 1994.
To evaluate the influence of perfusion temperature on systemic effects of cardiopulmonary bypass (CPB), 30 patients undergoing elective coronary artery bypass grafting were randomly assigned to either normothermic (warm, n = 14, 36°C) or hypothermic (cold, n = 16, 28°C) CPB. Serial hemodynamic measurements and blood samples were obtained before, during and after the CPB procedure. During CPB, there were no differences between both groups in the need for vasopressors (norepinephrine, phenylephrine), urinary output, or fluid balance. In the early postoperative period, normothermic CPB patients had significantly lower systemic vascular resistance and higher cardiac index measurements (mean ± standard error: systemic vascular resistance, 880 ± 27 versus 1,060 ± 57 dyne • s • cm-5, p = 0.025; cardiac index, 3.6 ± 0.1 versus 2.9 ± 0.1 L • min-1 • m-2, p = 0.01) without differences in the administration of vasoactive drugs. Blood loss was significantly higher in patients after hypothermic CPB (median [range] body surface area: 370 [180–560] versus 490 [280–2,120] mL/m2, p = 0.0006), with a greater need for transfusion of erythrocytes and fresh frozen plasma. Plasma levels of tumor necrosis factor and soluble tumor necrosis factor receptors increased during and after CPB, independent of perfusion temperature. This study suggests a significant influence of CPB temperature and respective perfusion management on postoperative hemodynamics and blood loss. Normothermic CPB is not associated with additional systemic adverse effects.
This article has been cited by other articles:
|
|
 |
|
  G. S. Murphy, E. A. Hessel II, and R. C. Groom Optimal Perfusion During Cardiopulmonary Bypass: An Evidence-Based Approach Anesth. Analg., May 1, 2009; 108(5): 1394 - 1417. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. R. Srivastava, A. Banerjee, D. K. Tempe, B. Mishra, V. Muppiri, S. Narang, H. Singh, and S. Virmani A comprehensive approach to fast tracking in cardiac surgery: ambulatory low-risk open-heart surgery Eur. J. Cardiothorac. Surg., June 1, 2008; 33(6): 955 - 960. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V Kvalheim, M Farstad, O Haugen, H Brekke, A Mongstad, E Nygreen, and P Husby A hyperosmolar-colloidal additive to the CPB-priming solution reduces fluid load and fluid extravasation during tepid CPB Perfusion, January 1, 2008; 23(1): 57 - 63. [Abstract] [PDF]
|
|
|
|
 |
|
 E. Bezon, Y. A. Maguid, G. Gueret, J. N. Choplain, A. A. Aziz, and J. A. Barra Wrapping of the Left Internal Thoracic Artery With an Expanded Polytetrafluoroethylene Membrane Ann. Thorac. Surg., January 1, 2006; 81(1): 383 - 385. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kaukuntla, A. Walker, D. Harrington, T. Jones, and R. S. Bonser Differential brain and body temperature during cardiopulmonary bypass--a randomised clinical study Eur. J. Cardiothorac. Surg., September 1, 2004; 26(3): 571 - 579. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kaukuntla, D. Harrington, I. Bilkoo, T. Clutton-Brock, T. Jones, and R. S. Bonser Temperature monitoring during cardiopulmonary bypass--do we undercool or overheat the brain? Eur. J. Cardiothorac. Surg., September 1, 2004; 26(3): 580 - 585. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Flynn, S. Reddy, W. Shepherd, C. Holmes, D. Armstrong, C. Lunn, K. Khan, and S. Kendall Fast-tracking revisited: routine cardiac surgical patients need minimal intensive care Eur. J. Cardiothorac. Surg., January 1, 2004; 25(1): 116 - 122. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Gaudino, R. Zamparelli, F. Andreotti, F. Burzotta, L. Iacoviello, F. Glieca, M. B. Donati, A. Maseri, R. Schiavello, and G. Possati Normothermia does not improve postoperative hemostasis nor does it reduce inflammatory activation in patients undergoing primary isolated coronary artery bypass J. Thorac. Cardiovasc. Surg., June 1, 2002; 123(6): 1092 - 1100. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Slater, T. A. Orszulak, K. J. Zehr, and D. J. Cook Use of the Cobra catheter for targeted temperature management during cardiopulmonary bypass in swine J. Thorac. Cardiovasc. Surg., May 1, 2002; 123(5): 936 - 942. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. H. Rehfeldt and D. J. Cook Transesophageal Echocardiographic Imaging of a New Aortic Cannula for Differential Perfusion During Cardiopulmonary Bypass Anesth. Analg., February 1, 2001; 92(2): 338 - 340. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. S. Boston, H. Sungurtekin, C. G.A. McGregor, J. A. Macoviak, and D. J. Cook Differential perfusion: a new technique for isolated brain cooling during cardiopulmonary bypass Ann. Thorac. Surg., May 1, 2000; 69(5): 1346 - 1350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-P. Yared, N. J. Starr, F. K. Torres, C. A. Bashour, G. Bourdakos, M. Piedmonte, J. A. Michener, J. A. Davis, and T. E. Rosenberger Effects of single dose, postinduction dexamethasone on recovery after cardiac surgery Ann. Thorac. Surg., May 1, 2000; 69(5): 1420 - 1424. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Shimamoto, S. Kanemitsu, K. Fujinaga, M. Takao, K. Onoda, T. Shimono, K. Tanaka, H. Shimpo, and I. Yada Biocompatibility of silicone-coated oxygenator in cardiopulmonary bypass Ann. Thorac. Surg., January 1, 2000; 69(1): 115 - 120. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Jones and R. C. Roy Should patients be normothermic in the immediate postoperative period? Ann. Thorac. Surg., October 1, 1999; 68(4): 1454 - 1455. [Full Text] [PDF]
|
|
|
|
|
|
D. J. Cook Changing Temperature Management for Cardiopulmonary Bypass Anesth. Analg., June 1, 1999; 88(6): 1254 - 1254. [Full Text] [PDF]
|
|
|
|
|
|
P. E. Stensrud, G. A. Nuttall, M. A. de Castro, M. D. Abel, M. H. Ereth, W. C. Oliver Jr, S. C. Bryant, and H. V. Schaff A prospective, randomized study of cardiopulmonary bypass temperature and blood transfusion Ann. Thorac. Surg., March 1, 1999; 67(3): 711 - 715. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. M. Jacquet, P. H. Noirhomme, M. J. Van Dyck, G. A. El Khoury, A. J. Matta, M. J. Goenen, and R. A. Dion Randomized trial of intermittent antegrade warm blood versus cold crystalloid cardioplegia Ann. Thorac. Surg., February 1, 1999; 67(2): 471 - 477. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. F. Corno and L. K. von Segesser Is hypothermia necessary in pediatric cardiac surgery? Eur. J. Cardiothorac. Surg., January 1, 1999; 15(1): 110 - 111. [Full Text] [PDF]
|
|
|
|
|
|
S. Ashraf, J. Butler, Y. Tian, D. Cowan, S. Lintin, N. R. Saunders, K. G. Watterson, and P. G. Martin Inflammatory Mediators in Adults Undergoing Cardiopulmonary Bypass: Comparison of Centrifugal and Roller Pumps Ann. Thorac. Surg., February 1, 1998; 65(2): 480 - 484. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Ranucci, G Soro, A Frigiola, L Menicanti, A Ditta, G Candido, and S Tambalo Normothermic perfusion and lung function after cardiopulmonary bypass: effects in pulmonary risk patients Perfusion, September 1, 1997; 12(5): 309 - 315. [Abstract] [PDF]
|
|
|
|
|
|
T. Ohata, Y. Sawa, K. Kadoba, T. Masai, H. Ichikawa, and H. Matsuda Effect of Cardiopulmonary Bypass Under Tepid Temperature on Inflammatory Reactions Ann. Thorac. Surg., July 1, 1997; 64(1): 124 - 128. [Abstract] [Full Text]
|
|
|
|
|
|
M. Tonz, O. N. Krogmann, O. M. Hess, B. Leskosek, T. Mihaljevic, L. K. von Segesser, and M. I. Turina Effect of Intermittent Warm Blood Cardioplegia on Functional Recovery After Prolonged Cardiac Arrest Ann. Thorac. Surg., October 1, 1996; 62(4): 1146 - 1151. [Abstract] [Full Text]
|
|
|
|
|
|
I. Regragui, I. Birdi, M. Bashar Izzat, A. M. S. Black, A. Lopatatzidis, C. J. E. Day, F. Gardner, A. J. Bryan, and G. D. Angelini THE EFFECTS OF CARDIOPULMONARY BYPASS TEMPERATURE ON NEUROPSYCHOLOGIC OUTCOME AFTER CORONARY ARTERY OPERATIONS: A PROSPECTIVE RANDOMIZED TRIAL J. Thorac. Cardiovasc. Surg., October 1, 1996; 112(4): 1036 - 1045. [Abstract] [Full Text]
|
|
|
|
|
|
I. Birdi, M. B. Izzat, A. J. Bryan, and G. D. Angelini Normothermic Techniques During Open Heart Operations Ann. Thorac. Surg., May 1, 1996; 61(5): 1573 - 1580. [Abstract] [Full Text]
|
|
|
|
|
|
O. Gil, J. C. Catala, A. L. Fernandez, J. A. Montero, D. Luna, O. Tovar, M. Tonz, T. Mihaljevic, L. K. von Segesser, and M. I. Turina Normothermia, Hypothermia, and Postoperative Bleeding Ann. Thorac. Surg., October 1, 1995; 60(4): 1160 - 1161. [Full Text]
|
|
|
|
|
|
I. Birdi, I. A. Regragui, M. B. Izzat, A. J. Bryan, G. D. Angelini, R. M. Becker, A. A. Rich, M. Tonz, T. Mihaljevic, L. K. von Segesser, et al. Effects of Cardiopulmonary Perfusion Temperature: A Randomized, Controlled Trial Ann. Thorac. Surg., September 1, 1995; 60(3): 747 - 748. [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
