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Clarence H. Owen
Robin G. Cummings
Timothy L. Sell
Robert H. Jones
Donald D. Glower
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Ann Thorac Surg 1994;58:1729-1733
© 1994 The Society of Thoracic Surgeons


Articles

Coronary artery bypass grafting in patients with dialysis-dependent renal failure

Clarence H. Owen, MD, Robin G. Cummings, MD, Timothy L. Sell, MD, Steve J. Schwab, MD, Robert H. Jones, MD, Donald D. Glower, MD*

Department of Surgery and Medicine, Duke University Medical Center, Durham, North Carolina USA

Accepted for publication June 8, 1994.

* Address reprint requests to Dr Glower, Duke University Medical Center, Box 3851, Durham, NC 27710.

Few data exist regarding functional results and long-term survival after coronary bypass in patients on dialysis. Therefore, a retrospective analysis was performed of 21 consecutive patients with dialysis-dependent renal failure who were undergoing coronary artery bypass grafting. Preoperatively, all but 1 patient had associated comorbid illnesses, 15 patients (71%) had class IV angina, and 16 patients (76%) had either left main or three-vessel disease. There were two perioperative deaths (9%), and complications occurred in 10 of the 21 patients (48%). All 19 hospital survivors showed symptomatic improvement with improved overall functional status (mean Karnof sky score increased from 37% ± 16% preoperatively to 69% ± 9% at hospital discharge or death; p < 0.001). Actuarial survival rates were 84% ± 8% and 45% ± 13% at 1 and 2 years, respectively. Therefore, coronary bypass grafting may be performed in dialysis patients with increased but acceptable morbidity and mortality, with excellent symptomatic relief, and with improved functional status. However, limited long-term survival suggests that the relative costs and benefits of surgical revascularization need further examination in this patient population.




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