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Ann Thorac Surg 1994;58:1670-1673
© 1994 The Society of Thoracic Surgeons

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Articles

Regression of left ventricular mass after mitral valve repair of pure mitral regurgitation

^a Department of Emergency Medicine, Shin-Kong Memorial Hospital, Taipei Taiwan, Republic of China
^b Departments of Internal Medicine and Surgery, National Taiwan Univesaity Hospital, Taipei, Taiwan, Republic of China

Accepted for publication May 26, 1994.

^_* Address reprint requests to Dr Lien, Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Rd, Taipei 100, Taiwan, Republic of China.

To evaluate the effect of mitral valve repair on the regression of left ventricular mass, we studied 50 consecutive patients with severe, pure mitral regurgitation undergoing mitral valve repair. Two-dimensional echocardiograms were recorded a mean 2.5 ± 2.0 weeks before and 6.5 ± 2.5 months after valve operation. Postoperative significant mitral regurgitation was present in 3 patients. After mitral valve repair there were significant decreases in left ventricular end-diastolic volume index (133 ± 39 mL/m² to 79 ± 35 mL/m²; p < 0.001), end-systolic volume index (44 ± 26 mL/m² to 30 ± 26 mL/m²; p < 0.001), stroke volume index (89 ± 29 mL/m² to 49 ± 19 mL/m²; p < 0.001), and mass index (211 ± 82 g/m² to 134 ± 52 g/m²; p < 0.001). There also were significant decreases in left atrial dimension (47 ± 9 mm to 38 ± 9 mm; p < 0.001), left ventricular end-diastolic dimension (61 ± 8 mm to 48 ± 7 mm; p < 0.001), and end-systolic dimension (39 ± 8 mm to 32 ± 7 mm; p < 0.001). Left ventricular ejection fraction decreased slightly from 0.69 ± 0.12 to 0.64 ± 0.12; p < 0.01) after repair. Thus, correction of pure mitral regurgitation leads to reduction of the cardiac chamber size and left ventricular volumes as well as regression of the left ventricular mass.

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