| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Annals of Thoracic Surgery, Vol 58, 1515-1520, Copyright © 1994 by The Society of Thoracic Surgeons
HR Levin, JM Chen, MC Oz, KA Catanese, H Krum, RL Goldsmith, M Packer and EA Rose
Left ventricular assist devices (LVADs) increasingly are being used as a
bridge to transplantation. We studied changes in New York Heart Association
class, mean arterial pressure, resting cardiac output, end- organ function,
exercise oxygen consumption, and exercise cardiac output in 12 LVAD
recipients. In addition, resting levels of neurohormonal factors were
evaluated 4 to 16 weeks after implantation. Two of the 12 patients died of
right heart failure and 1 of aspiration; all deaths occurred in the first 2
weeks after LVAD implantation. Of the other 9 patients, 8 improved to New
York Heart Association class I and 1 to class II, all of whom were in class
IV preoperatively. The 4 patients who underwent exercise testing achieved
an exercise oxygen consumption of 15.0 +/- 2.7 mL.kg-1.min-1, which was
paralleled by an increase in resting cardiac output from 3.07 +/- 0.9
L.min-1 preoperatively to 5.66 +/- 1.1 L.min-1 at 2 months, and mean
arterial pressure from 60 +/- 8 to 91 +/- 10 mm Hg at 2 months, a benefit
that was maintained for up to 10 months. End-organ function revealed
comparable improvement at 2 months for both creatinine (1.68 +/- 0.7 to 1.0
+/- 0.19 mg.dL-1) and total bilirubin (1.37 +/- 1.17 to 0.54 +/- 0.26
mg.dL-1) levels. Levels of neurohormones were within normal limits. Adverse
clinical events after the perioperative period were minimal, and no
thromboembolic complications occurred.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Potential of left ventricular assist devices as outpatient therapy while awaiting transplantation
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York.
This article has been cited by other articles:
|
|
 |
|
  S. Klotz, A. Barbone, S. Reiken, J. W. Holmes, Y. Naka, M. C. Oz, A. R. Marks, and D. Burkhoff Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties J. Am. Coll. Cardiol., March 1, 2005; 45(5): 668 - 676. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Park, J. Zhang, Y. Ye, S. Ormaza, P. Liang, A. J. Bank, L. W. Miller, and R. J. Bache Myocardial creatine kinase expression after left ventricular assist device support J. Am. Coll. Cardiol., June 5, 2002; 39(11): 1773 - 1779. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Barbone, J. W. Holmes, P. M. Heerdt, A. H.S. The', Y. Naka, N. Joshi, M. Daines, A. R. Marks, M. C. Oz, and D. Burkhoff Comparison of Right and Left Ventricular Responses to Left Ventricular Assist Device Support in Patients With Severe Heart Failure: A Primary Role of Mechanical Unloading Underlying Reverse Remodeling Circulation, August 7, 2001; 104(6): 670 - 675. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. de Jonge, H. Kirkels, J. R. Lahpor, C. Klopping, E. J. Hulzebos, A. Brutel de la Riviere, and E. O. Robles de Medina Exercise performance in patients with end-stage heart failure after implantation of a left ventricular assist device and after heart transplantation: An outlook for permanent assisting? J. Am. Coll. Cardiol., June 1, 2001; 37(7): 1794 - 1799. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. L.S. Morales, K. A. Catanese, D. N. Helman, M. R. Williams, A. Weinberg, D. J. Goldstein, E. A. Rose, and M. C. Oz SIX-YEAR EXPERIENCE OF CARING FOR FORTY-FOUR PATIENTS WITH A LEFT VENTRICULAR ASSIST DEVICE AT HOME: SAFE, ECONOMICAL, NECESSARY J. Thorac. Cardiovasc. Surg., February 1, 2000; 119(2): 251 - 259. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Bartling, H. Milting, H. Schumann, D. Darmer, L. Arusoglu, M. M. Koerner, A. El-Banayosy, R. Koerfer, J. Holtz, and H.-R. Zerkowski Myocardial Gene Expression of Regulators of Myocyte Apoptosis and Myocyte Calcium Homeostasis During Hemodynamic Unloading by Ventricular Assist Devices in Patients With End-Stage Heart Failure Circulation, November 9, 1999; 100(90002): II-216 - 223. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. L. Mann and J. T. Willerson Left Ventricular Assist Devices and the Failing Heart : A Bridge to Recovery, a Permanent Assist Device, or a Bridge Too Far? Circulation, December 1, 1998; 98(22): 2367 - 2369. [Full Text] [PDF]
|
|
|
|
|
|
D. M. Mancini, A. Beniaminovitz, H. Levin, K. Catanese, M. Flannery, M. DiTullio, S. Savin, M. E. Cordisco, E. Rose, and M. Oz Low Incidence of Myocardial Recovery After Left Ventricular Assist Device Implantation in Patients With Chronic Heart Failure Circulation, December 1, 1998; 98(22): 2383 - 2389. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. E. Pae Jr, J. M. Anderson, E. H. Blackstone, H. S. Boroevetz, A. Ciarkowski, J. G. Copeland III, M. R. Costanzo-Nordin, K. Daase, M. A. Dew, M. J. Domanski, et al. Bethesda conference: conference for the design of clinical trials to study circulatory support devices for chronic heart failure Ann. Thorac. Surg., October 1, 1998; 66(4): 1452 - 1465. [Full Text] [PDF]
|
|
|
|
|
|
A. Zafeiridis, V. Jeevanandam, S. R. Houser, and K. B. Margulies Regression of Cellular Hypertrophy After Left Ventricular Assist Device Support Circulation, August 18, 1998; 98(7): 656 - 662. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. H. Lee, N. Doliba, M. Osbakken, M. Oz, and D. Mancini Improvement of myocardial mitochondrial function after hemodynamic support with left ventricular assist devices in patients with heart failure J. Thorac. Cardiovasc. Surg., August 1, 1998; 116(2): 344 - 349. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Dipla, J. A. Mattiello, V. Jeevanandam, S. R. Houser, and K. B. Margulies Myocyte Recovery After Mechanical Circulatory Support in Humans With End-Stage Heart Failure Circulation, June 16, 1998; 97(23): 2316 - 2322. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Deng, M. J. Wilhelm, H. H. Scheld, B. E. Jaski, and J. Kim Effects of Exercise During Long-term Support With a Left Ventricular Assist Device • Response Circulation, March 31, 1998; 97(12): 1212 - 1213. [Full Text] [PDF]
|
|
|
|
|
|
S. Westaby, X. Y. Jin, T. Katsumata, D. P. Taggart, A. J. S. Coats, and O. H. Frazier Mechanical Support in Dilated Cardiomyopathy: Signs of Early Left Ventricular Recovery Ann. Thorac. Surg., November 1, 1997; 64(5): 1303 - 1308. [Abstract] [Full Text]
|
|
|
|
|
|
D. J. Goldstein, N. Moazami, J. A. Seldomridge, H. Laio, R. C. Ashton Jr, Y. Naka, D. J. Pinsky, and M. C. Oz Circulatory Resuscitation With Left Ventricular Assist Device Support Reduces Interleukins 6 and 8 Levels Ann. Thorac. Surg., April 1, 1997; 63(4): 971 - 974. [Abstract] [Full Text]
|
|
|
|
 |
|
 M. G. Massad and P. M. McCarthy Will permanent LVADs be better than heart transplantation? Eur. J. Cardiothorac. Surg., April 1, 1997; 11(suppl): S11 - S17. [Abstract] [PDF]
|
|
|
|
|
|
M. Vigano, S. Scuri, F. Cobelli, C. Opasich, F. M. Pagani, G. Minzioni, L. Martinelli, L. Tavazi, and M. Vigano Staged discharge out of hospital of the Novacor left ventricular assist system (LVAS) recipients Eur. J. Cardiothorac. Surg., April 1, 1997; 11(suppl): S45 - S50. [Abstract] [PDF]
|
|
|
|
|
|
O. Fey, A. El-Banayosy, L. Arosuglu, H. Posival, and R. Korfer Out-of-hospital experience in patients with implantable mechanical circulatory support: present and future trends Eur. J. Cardiothorac. Surg., April 1, 1997; 11(suppl): S51 - S53. [Abstract] [PDF]
|
|
|
|
|
|
J. P. Slater, E. A. Rose, H. R. Levin, O. H. Frazier, J. K. Roberts, A. D. Weinberg, and M. C. Oz Low Thromboembolic Risk Without Anticoagulation Using Advanced-Design Left Ventricular Assist Devices Ann. Thorac. Surg., November 1, 1996; 62(5): 1321 - 1327. [Abstract] [Full Text]
|
|
|
|
|
|
M. Miyama, W. C. Dihmis, P. H. Deleuze, Y. Uozaki, S. L. Bambang, F. Pasteau, N. Rostaqui, and D. Y. Loisance The Gastrointestinal Tract: An Underestimated Organ as Demonstrated in an Experimental LVAD Pig Model Ann. Thorac. Surg., March 1, 1996; 61(3): 817 - 822. [Abstract] [Full Text]
|
|
|
|
|
|
H. R. Levin, M. C. Oz, J. M. Chen, M. Packer, E. A. Rose, and D. Burkhoff Reversal of Chronic Ventricular Dilation in Patients With End-Stage Cardiomyopathy by Prolonged Mechanical Unloading Circulation, June 1, 1995; 91(11): 2717 - 2720. [Abstract] [Full Text]
|
|
|
|
 |
|
 T. McCarthy and D. Wheeldon Long-term blood pumping: an overview Perfusion, May 1, 1995; 10(3): 143 - 151. [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| ANN THORAC SURG | ASIAN CARDIOVASC THORAC ANN | EUR J CARDIOTHORAC SURG |
| J THORAC CARDIOVASC SURG | ICVTS | ALL CTSNet JOURNALS |
