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The Annals of Thoracic Surgery, Vol 58, 1161-1163, Copyright © 1994 by The Society of Thoracic Surgeons

ARTICLES

Carcinoid heart disease: early failure of an allograft valve replacement

SK Ohri, JB Schofield, H Hodgson, CM Oakley and BE Keogh
Department of Surgery, Hammersmith Hospital, Royal Postgraduate Medical School, London, England.

A woman who had carcinoid syndrome and carcinoid heart disease underwent tricuspid and pulmonary valve replacements with a xenograft and a cryopreserved allograft, respectively. Within 3 months of the operation severe pulmonary regurgitation and pulmonary hypertension refractory to medical therapy developed. Autopsy found the biomechanical tricuspid valve to be free of disease but the allograft in the pulmonary position was involved by carcinoid heart disease in a fashion similar to the excised native pulmonary valve.


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