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The Annals of Thoracic Surgery, Vol 58, 533-535, Copyright © 1994 by The Society of Thoracic Surgeons
P Menasche
A pig model of cardiopulmonary bypass and cardioplegic arrest was used to
compare leakage around manually inflatable and autoinflatable retrograde
coronary sinus cardioplegia catheters. Warm and cold blood cardioplegia
were alternately delivered through the catheter under study at both low (16
to 24 mm Hg) and high (30 to 40 mm Hg) perfusion pressures. During each
experiment, the coronary sinus ostium was sealed around the shaft of the
retrograde cannula so that all backflow occurring during cardioplegia
delivery could be collected by a separate drainage catheter inserted
directly into the coronary sinus approximately midway between the right
atrium and the distal end of the balloon. Only two of the 52 manually
inflatable cannulas leaked. The leakage in both cases was negligible (<
1% of the total retrograde cardioplegia flow). In contrast, leakage
occurred with 57 of the 73 autoinflatable devices tested (p < 0.0001)
and averaged 22% +/- 3% (mean +/- the standard error of the mean) of the
total retrograde flow. The temperature of the cardioplegia solution had no
effect on leakage. These results suggest that autoinflatable balloons
inconsistently seal the coronary sinus during cardioplegia infusion,
thereby decreasing the amount of flow that effectively reaches the
myocardium. This should make surgeons cautious about using them with warm
blood cardioplegia, which largely relies upon the delivery of sufficiently
high retrograde nutritive flows for preventing cardioprotective aerobic
arrest from becoming a life-threatening ischemic arrest.
ARTICLES
Experimental comparison of manually inflatable versus autoinflatable retrograde cardioplegia catheters
Department of Cardiovascular Surgery, Hopital Lariboisiere, Paris, France.
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