HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Lonn, U. Articles by Casimir-Ahn, H. Search for Related Content PubMed PubMed Citation Articles by Lonn, U. Articles by Casimir-Ahn, H.

The Annals of Thoracic Surgery, Vol 58, 516-518, Copyright © 1994 by The Society of Thoracic Surgeons

ARTICLES

Coronary artery operation supported by the Hemopump: an experimental study on pig

U Lonn, B Peterzen, H Granfeldt and H Casimir-Ahn
Linkoping Heart Center, University of Linkoping, Sweden.

Twelve pigs undergoing coronary artery bypass grafting had the Hemopump to decompress the heart and as circulatory support. The pigs also were given a short-acting beta-blocker, esmolol, to make the heart flaccid. Extracorporeal circulation was not used. During Hemopump support, a bolus dose of 0.5 to 5 mg/kg of esmolol was given before incremental titration steps from 100 to 600 micrograms.kg-1.min-1 over 15 to 20 minutes. The internal thoracic artery was sutured to the distal part of the left anterior descending artery. The Hemopump was withdrawn to the aorta after a weaning period of 20 to 30 minutes. Seven of 12 pigs went through the whole procedure and the Hemopump was weaned off without complications. Five animals died due to right ventricular failure in association with esmolol administration. There was a big interindividual difference in esmolol dose-response curves in the surviving animals. No significant differences in the hemodynamic variables were observed during the experiment. The Hemopump in combination with a short-acting beta-blocker could be an alternate way of performing coronary artery bypass grafting in selected patients.

This article has been cited by other articles:

				M. S. Sweeney The Hemopump in 1997: a clinical, political, and marketing evolution Ann. Thorac. Surg., August 1, 1999; 68(2): 761 - 763. [Abstract] [Full Text] [PDF]

				U. Lonn, B. Peterzen, B. Carnstam, and H. Casimir-Ahn Beating heart coronary surgery supported by an axial blood flow pump Ann. Thorac. Surg., January 1, 1999; 67(1): 99 - 104. [Abstract] [Full Text] [PDF]

				U. Lonn, J. Wulff, K.-Y. Keck, B. Wranne, P. Ask, B. Peterzen, and H. Casimir-Ahn Flow Characteristics of the Hemopump: An Experimental In Vitro Study Ann. Thorac. Surg., January 1, 1997; 63(1): 162 - 166. [Abstract] [Full Text]