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Ann Thorac Surg 1994;58:250-251
© 1994 The Society of Thoracic Surgeons

Articles

Limbic encephalitis secondary to malignant thymoma

John D. Cunningham, MD*, Michael E. Burt, MD, PhD

Thoracic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York USA

Accepted for publication November 6, 1993.

* Address reprint requests to Dr Burt, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021.

A 56-year-old woman presented with memory loss and an enlarging mediastinal mass on chest roentgenogram. Physical findings were normal except for an altered mental status examination consistent with dementia. Further radiologic assessment was nondiagnostic. Surgical resection of a malignant thymoma resulted in clinical improvement. Treatment for limbic encephalitis should be directed at the underlying disease, and symptoms may improve if the tumor is eradicated.




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