The Annals of Thoracic Surgery, Vol 57, 1579-1583, Copyright © 1994 by The Society of Thoracic Surgeons
Chronic cardiac rejection masking as constrictive pericarditis
TJ Hinkamp, HJ Sullivan, A Montoya, S Park, L Bartlett and R Pifarre
Loyala University Medical Center, Maywood, Illinois 60153.
The hemodynamic changes consistent with constrictive pericarditis are often
encountered in patients who have undergone cardiac transplantation. We
describe here 4 patients who underwent pericardiectomy after cardiac
transplantation. All were found to have evidence of a thickened and
constricting peel of pericardium at surgical exploration. Their
postoperative clinical courses were variable. One patient with primarily
effusive constriction experienced marked improvement. Three patients failed
to show clinical improvement and had persistently elevated atrial and
ventricular end-diastolic pressures. A coexisting restrictive
cardiomyopathy secondary to chronic rejection, coronary arteriopathy, or
long-standing constriction may have been the cause of this poor outcome.
Many patients with transplanted hearts exhibit evidence of poor diastolic
ventricular compliance without evidence of classic constriction; some
manifest both the restrictive and constrictive components. The careful
selection of patients with constrictive pericarditis can optimize the
outcome.