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The Annals of Thoracic Surgery, Vol 57, 1319-1320, Copyright © 1994 by The Society of Thoracic Surgeons

ARTICLES

Aortic homograft and mitral valve repair in a patient with Werner's syndrome

T Carrel, M Pasic, T Tkebuchava, J Turina, R Jenni and MI Turina
Clinic for Cardiovascular Surgery, University Hospital, Zurich, Switzerland.

We report the case of a 66-year-old man suffering from Werner's syndrome (adult progeria); he presented with several cardiac disorders, including coronary artery disease, aortic stenosis, and mitral regurgitation, mainly due to calcific deposits in the mitral annulus and the aortic cusps. Treatment consisted of mitral repair, homograft replacement of the aortic valve, and coronary artery bypass grafting. Avoidance of prosthetic material because of chronic infectious skin ulcers constituted the main goal of the operation.

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