ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Gregory A. Thomas
Robert Fietsam, Jr
Larry W. Stephenson
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nakajima, H.
Right arrow Articles by Stephenson, L. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nakajima, H.
Right arrow Articles by Stephenson, L. W.

Ann Thorac Surg 1994;57:912-920
© 1994 The Society of Thoracic Surgeons

Articles

Chronic morphologic changes of skeletal muscle ventricles in circulation

Hidehiro Nakajima, MD, Hisako O. Nakajima, MD, Gregory A. Thomas, MD, Robert L. Hammond, BA, Frank W. Mocek, MD, Robert Fietsam, Jr, MD, Albert Pochettino, MD, Huiping Lu, MD, Ali D. Spanta, MD, Susumu Isoda, MD, Larry W. Stephenson, MD*

Division of Cardiothoracic Surgery, Wayne State University, Detroit, Michigan, USA

Accepted for publication July 27, 1993.

* Address reprint requests to Dr Stephenson, Division of Cardiothoracic Surgery, Wayne State University, Suite 228, Harper Professional Building, 4160 John R St, Detroit, MI 48201.

Skeletal muscle ventricles (SMVs) werp constructed either extrathoracically or intrathoracically in 44 dogs using the left latissimus dorsi muscle. These SMVs functioned as aortic counterpulsators for from several hours to 216 days. In this study, the relationship between the morphologic changes in the SMVs and their time course in the circulation was evaluated retrospectively. The average volume of the SMV chamber after it had been excised and fixed in formalin was 21.3 ± 11.0 mL (mean ± the standard deviation) for extrathoracic SMVs and 20.0 ± 7.5 mL for intrathoracic SMVs. The volume of the SMV chamber did not correlate with the time course in the circulation. The SMV wall was mainly composed of three components: muscular, fibrous, and fatty aspects. The overall thickness of the wall appeared to be preserved over time in the circulation. However, the thickness of the muscular component tended to decrease over time. SMV rupture occurred in 15 dogs between postoperative days 4 and 39. All ruptures occurred at the suture line between the SMV and the vascular conduits. There was some degree of thrombus in 24 SMVs. Before SMVs can be applied clinically for the purpose of cardiac assist, problems with rupture and thrombus formation must be solved. A better understanding of the morphologic changes that take place in the SMV over time also is needed.




This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
K. J. Gustafson, J. D. Sweeney, J. Gibney, and L. A. Fiebig-Mathine
Skeletal muscle ventricle pressure-volume properties conform to dynamic and static conditioning
Ann. Thorac. Surg., September 1, 2003; 76(3): 828 - 835.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
B. G. Patel, S. H. Shah, L. I. Astra, R. L. Hammond, Z. A. Sharif, P. J. McDonald, and L. W. Stephenson
Skeletal muscle ventricle aortic counterpulsation: function during chronic heart failure
Ann. Thorac. Surg., February 1, 2002; 73(2): 588 - 593.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
G. A. Thomas, R. L. Hammond, K. Greer, H. Lu, J. C. Jarvis, A. P. Shortland, D. M. Pullan, S. Salmons, and L. W. Stephenson
Functional assessment of skeletal muscle ventricles after pumping for up to four years in circulation
Ann. Thorac. Surg., October 1, 2000; 70(4): 1281 - 1289.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
K. A. Greer, H. Lu, A. D. Spanta, R. L. Hammond, and L. W. Stephenson
Skeletal Muscle Ventricles, Left Ventricular Apex-to-Aorta Configuration: 1 to 11 Weeks in Circulation
Circulation, January 21, 1997; 95(2): 497 - 502.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
G. A. Thomas, S. Isoda, R. L. Hammond, H. Lu, H. Nakajima, H. O. Nakajima, K. Greer, S. J. Gilroy, S. Salmons, and L. W. Stephenson
Pericardium-Lined Skeletal Muscle Ventricles: Up to Two Years' In-Circulation Experience
Ann. Thorac. Surg., December 1, 1996; 62(6): 1698 - 1706.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
G. A. Thomas, H. Lu, S. Isoda, R. L. Hammond, H. Nakajima, H. O. Nakajima, and L. W. Stephenson
Skeletal Muscle Ventricles in Circulation: Decreased Incidence of Rupture
Ann. Thorac. Surg., January 1, 1996; 61(1): 430 - 436.
[Abstract] [Full Text]

Home page
 PerfusionHome page
T. McCarthy and D. Wheeldon
Long-term blood pumping: an overview
Perfusion, May 1, 1995; 10(3): 143 - 151.
[PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
G. A. Thomas, P. I. Lelkes, S. Isoda, D. Chick, H. Lu, R. L. Hammond, H. Nakajima, H. Nakajima, H. L. Walters III, and L. W. Stephenson
Endothelial cell-lined skeletal muscle ventricles in circulation
J. Thorac. Cardiovasc. Surg., January 1, 1995; 109(1): 66 - 73.
[Abstract] [Full Text]

Home page
 Ann. Thorac. Surg.Home page
G. A. Thomas, H. Lu, S. Isoda, R. L. Hammond, H. Nakajima, H. O. Nakajima, M. Colson, and L. W. Stephenson
Pericardium-lined skeletal muscle ventricles in circulation up to 589 days
Ann. Thorac. Surg., October 1, 1994; 58(4): 978 - 988.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1994 by The Society of Thoracic Surgeons.