HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mainwaring, R. D. Articles by Nelson, J. C. Search for Related Content PubMed PubMed Citation Articles by Mainwaring, R. D. Articles by Nelson, J. C.

The Annals of Thoracic Surgery, Vol 57, 59-63, Copyright © 1994 by The Society of Thoracic Surgeons

ARTICLES

Comparison of the hormonal response after bidirectional Glenn and Fontan procedures

RD Mainwaring, JJ Lamberti, JW Moore, GF Billman and JC Nelson
Division of Cardiac Surgery, Children's Hospital and Health Center, San Diego, California.

Fluid retention is a frequent complication after the bidirectional Glenn and Fontan procedures. It was our hypothesis that this fluid retention may have a hormonal basis. To test this hypothesis, we made serial determinations of antidiuretic hormone, cortisol, aldosterone, angiotensin, and renin before and after operation in patients undergoing a bidirectional Glenn (n = 15) or Fontan (n = 18) procedure. Patients undergoing a bidirectional Glenn procedure had elevations in antidiuretic hormone, cortisol, and aldosterone immediately after operation. However, none of the hormonal elevations persisted by the fifth postoperative day. In contrast, patients undergoing a Fontan procedure had elevations in antidiuretic hormone, cortisol, aldosterone, renin, and angiotensin II in the immediate postoperative period. Five days postoperatively, the renin and angiotensin II levels remained elevated compared with the preoperative values. The data demonstrate that patients undergoing a bidirectional Glenn procedure and those undergoing a Fontan procedure have different patterns of hormonal response. These results suggest that hormonal factors may contribute to fluid retention after these operations.

This article has been cited by other articles:

				L. S. Sun, C. Dominguez, N. A. Mallavaram, and J. M. Quaegebeur Dysfunction of atrial and B-type natriuretic peptides in congenital univentricular defects J. Thorac. Cardiovasc. Surg., May 1, 2005; 129(5): 1104 - 1110. [Abstract] [Full Text] [PDF]

				A. Gupta, C. Daggett, S. Behera, M. Ferraro, W. Wells, and V. Starnes Risk factors for persistent pleural effusions after the extracardiac Fontan procedure J. Thorac. Cardiovasc. Surg., June 1, 2004; 127(6): 1664 - 1669. [Abstract] [Full Text] [PDF]

				J. M. Simsic, S. M. Bradley, and D. M. Mulvihill Sodium nitroprusside infusion after bidirectional superior cavopulmonary connection: preserved cerebral blood flow velocity and systemic oxygenation J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 186 - 190. [Abstract] [Full Text] [PDF]

				V E Hjortdal, E V Stenbøg, H B Ravn, K Emmertsen, K T Jensen, E B Pedersen, K H Olsen, O K Hansen, and K E Sørensen Neurohormonal activation late after cavopulmonary connection Heart, April 1, 2000; 83(4): 439 - 443. [Abstract] [Full Text]

				R. D. Mainwaring, J. J. Lamberti, and T. E. Hugli Complement Activation and Cytokine Generation After Modified Fontan Procedure Ann. Thorac. Surg., June 1, 1998; 65(6): 1715 - 1720. [Abstract] [Full Text] [PDF]