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The Annals of Thoracic Surgery, Vol 57, 40-43, Copyright © 1994 by The Society of Thoracic Surgeons
D Navia, DM Cosgrove 3rd, BW Lytle, PC Taylor, PM McCarthy, RW Stewart, ER Rosenkranz and FD Loop
Reoperative coronary artery bypass grafting secondary to saphenous vein
graft (SVG) stenosis is a mushrooming problem. The internal thoracic artery
graft (ITA) provides superior long-term patency, but its flow is limited
and may be inadequate to meet large myocardial demands. To evaluate the
efficacy of the ITA as a replacement conduit for a stenotic SVG, 387
consecutive patients undergoing reoperative bypass grafting from 1985 to
1990 with a stenotic SVG to a totally obstructed left anterior descending
coronary artery (LAD) were analyzed. The patients were divided into four
groups according to the management of the previously placed SVG. Group I (n
= 155) underwent graft replacement with a new SVG. Group II (n = 90)
received an ITA with the old SVG left intact. In group III (n = 37), an ITA
was placed to the LAD with an SVG to the diagonal (old graft interrupted).
Group IV (n = 104) had an ITA only to the LAD (old graft interrupted).
There were 14 deaths (3.6%). Mortality rate was 7.9% for group IV and 2.1%
for groups I through III (p = 0.01). Multivariate analyses identified
advancing age (p = 0.001), ITA only (p = 0.001), and female sex (p = 0.04)
as independent predictors of operative mortality. Evidence of hypoperfusion
in the distribution of the LAD was present in 19 patients, all of whom were
in group IV (18.9%). Predictors of hypoperfusion were moderate/severe left
ventricular function (p = 0.02) and ITA to the LAD with interruption of the
old graft (p = 0.0001).(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Is the internal thoracic artery the conduit of choice to replace a stenotic vein graft?
Cleveland Clinic Foundation, Ohio 44195.
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